Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07617753RecruitingPhase 1/Phase 2
CAR-NK Cell Therapy for Recurrent Ovarian Cancer
This trial tests a new type of cell therapy using modified natural killer cells (CAR-NK cells) that are trained to attack ovarian cancer cells. It's designed for patients whose cancer has come back or stopped responding to previous treatments.
Shenzhen, GuangdongAges 18–75 - NCT07613307RecruitingPhase 3
Study of a new pill for type 2 diabetes during Ramadan fasting
This study tests an oral medication called orforglipron to see if it safely helps people with type 2 diabetes manage their blood sugar while they fast during Ramadan. You may be a good fit if you are planning to fast and your diabetes is not too severe.
AgraAges 18–65 - NCT07614152RecruitingPhase 3
Growth hormone treatment for girls with Turner syndrome
This study tests whether a new long-acting growth hormone injection helps girls with Turner syndrome grow taller. Turner syndrome is a genetic condition that affects growth, and this trial will see if this treatment is safe and effective.
AnyangAges 2–12 - NCT07619131RecruitingPhase 3
New cholesterol-lowering combination pill for at-risk adults
This study tests a new combination pill containing two cholesterol-lowering medications (laroprovstat and rosuvastatin) in people who have never taken cholesterol medicine before. The goal is to see if the combination works better than either medicine alone at lowering LDL cholesterol, which is the 'bad' cholesterol that can increase heart disease risk.
Dothan, AlabamaAges 18–130 - NCT07619820RecruitingPhase 1
CSL300 Safety Study for Kidney Dialysis Patients
This study tests how a new drug called CSL300 (clazakizumab) works in the body of people with end-stage kidney disease who are on dialysis. Researchers want to understand if it's safe and how your body processes it.
BeijingAges 18 years+ - NCT07619118RecruitingPhase 3
Laroprovstat and rosuvastatin vs. rosuvastatin for high cholesterol
This trial tests whether adding a new medicine, laroprovstat, to a standard cholesterol drug (rosuvastatin) is better at lowering bad cholesterol than the standard drug alone. It might help people who are at high risk for heart disease or stroke.
Sun City West, ArizonaAges 18–130 - NCT07612891RecruitingPhase 1/Phase 2
Testing INV-6452 for advanced breast cancer and solid tumors
This study tests a new drug called INV-6452 to see if it is safe and can help control advanced cancers that have grown despite prior treatment. The drug targets specific cancer cell weaknesses, particularly in hormone-sensitive breast cancers without HER2 mutations.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07615400Recruiting
Long-term study of people with fucosidosis
This study follows people with fucosidosis over time to learn more about how the condition progresses. It is an observational study, so participants do not receive any new treatment—just regular health monitoring to help researchers better understand the disease.
Orange, CaliforniaAges Any age - NCT07617961Recruiting
THERAVEX Spray for Wound and Ulcer Healing
This trial tests a topical spray treatment designed to help heal various types of skin wounds, including burns, pressure sores, and diabetic ulcers. The spray may help your wound heal faster and more effectively.
BarcelonaAges 18 years+ - NCT06704321Recruiting
Effects of TOTUM-448 on liver fat and heart health
This trial tests a supplement called TOTUM-448 to see if it can reduce liver fat and improve heart health in people with a fatty liver condition (MASLD). If you have excess liver fat and are overweight, this study could help find new ways to manage your condition.
Québec, QuebecAges 18–75 - NCT06706700Recruiting
Biomarkers to predict cancer risk in pancreatic IPMN
This trial studies whether blood markers can help predict which pancreatic IPMNs are likely to become cancerous. If successful, it could help doctors decide when surgery is needed.
Milan, ItalyAges 18 years+ - NCT06706687Recruiting
Brain imaging and epigenetics in frontotemporal dementia and bipolar disorder
This study uses brain scans and genetic tests to understand the differences between behavioral variant frontotemporal dementia (bvFTD) and bipolar disorder. It may help improve diagnosis and find better treatments for both conditions.
Milan, MIAges 18 years+ - NCT05432362Recruiting
Energy sensing brain study in depression and weight groups
This study tests how the brain and body respond to “energy sensing” in people with depression and in people with different body weights. You may be asked to do assessments and follow specific health and diet rules so the researchers can compare groups.
Graz, StyriaAges 18–40 - NCT05281016Recruiting
Online family program to help children with weight
This study tests an online, family-based program (called the LITE Programme) to help children who are overweight. It may help improve healthy habits at home and support weight management.
SingaporeAges 6–12 - NCT06437353RecruitingPhase 2
Surufatinib combo for first-line and maintenance in high-risk ovarian cancer
This trial tests a combination of drugs (Surufatinib with carboplatin/paclitaxel) as first treatment for high-risk ovarian cancer, followed by a different combination (Surufatinib with olaparib) to keep the cancer from coming back. It aims to see if these targeted therapies work better than the standard approach.
Hefei, AnhuiAges 18–75 - NCT06708780RecruitingPhase 1
Treg cell therapy for type 1 diabetes
This trial tests whether giving your own regulatory T cells (a type of immune cell) back to you can help slow or stop the immune attack on your pancreas in type 1 diabetes. It is for people aged 8 to 65 who still make some insulin.
Nanjing, JiangsuAges 8–65 - NCT05957055RecruitingPhase 2
ADHD medicine compared for kids with type 1 diabetes
This Phase 2 study compares two ADHD medicines—lisdexamfetamine and methylphenidate—in children who have ADHD and type 1 diabetes. It’s designed to see which option works better and is safe/effective for managing ADHD without causing major problems for diabetes care.
Lodz, Łódź VoivodeshipAges 8 years–16.5 years - NCT06591286Recruiting
Real-time CGM for blood sugar after hospital discharge
This trial tests whether using a continuous glucose monitor (CGM) when you leave the hospital helps control blood sugar better. If you have type 2 diabetes and use insulin, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06709690Recruiting
AI-powered PET/MR scanner for children with suspected cancer
This study tests a new, fast, and quiet AI-powered PET/MR scanner to take detailed pictures of children with suspected cancer. It aims to make the imaging experience easier and more comfortable for kids.
Shanghai, Shanghai MunicipalityAges Up to 18 years - NCT07604610Recruiting
Heart Fat and Metabolic Health in Older Adults
This study looks at fat tissue around the heart and how it relates to metabolic health (blood sugar, cholesterol, weight) in people aged 50–70. Researchers will use ultrasound imaging to measure this fat and understand its connection to heart disease risk.
MoscowAges 50–70 - NCT07611721Recruiting
Testing a glucose monitor in critically ill surgery patients
This study tests whether a wearable glucose monitor (Dexcom G7) works well in patients in intensive care after major abdominal surgery or organ transplant who need insulin therapy. The monitor measures blood sugar continuously to help doctors manage insulin doses more safely.
PragueAges 18 years+ - NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Peoria, ArizonaAges 18 years+ - NCT07604974RecruitingPhase 2
Safety and effectiveness of ION775 for very high triglycerides
This trial tests a new medicine called ION775 to help lower very high triglyceride levels in the blood. Triglycerides are a type of fat, and having too much can increase heart disease risk. The study will check if ION775 is safe and actually works when added to your regular cholesterol medications.
Lincoln, CaliforniaAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Foley, AlabamaAges 18–75
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.