Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,607 recruiting studies in this area right now.
By phase
- Not applicable5,333
- Phase 2607
- Phase 1559
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 384
Top conditions
- Obesity620
- Ovarian Cancer335
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus183
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes130
- Metabolic Syndrome126
- Obesity & Overweight124
- Breast Cancer110
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Colorectal Cancer90
- Pancreas Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- Eli Lilly and Company41
- M.D. Anderson Cancer Center41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas158
- Massachusetts150
- New York142
- Colorado115
- Pennsylvania113
Recruiting studies7,607 total
- NCT07610798RecruitingPhase 1/Phase 2
Testing INV-8989 for Advanced Cancers With KRAS G12D Mutation
This early-stage trial tests a new drug called INV-8989 designed to target a specific genetic mutation (KRAS G12D) found in some advanced solid cancers. The study will evaluate whether the drug is safe and if it can help shrink tumors in patients who haven't responded to standard treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Foley, AlabamaAges 18–75 - NCT07605819Recruiting
Pancreatic Cancer Screening Test Study in Japan
This study tests a new blood test called the Enzeavour Assay to screen for early signs of pancreatic cancer in people without symptoms. If the test is positive, you may need imaging tests like an ultrasound or CT scan to confirm findings.
Nagakute, Aichi-kenAges 20 years+ - NCT05995782RecruitingPhase 1
Testing safety of FB418 in healthy people
This trial studies a new drug called FB418 to see if it's safe and how the body handles it. It first tests single doses in younger healthy men, then multiple doses, and also includes an optional group for healthy older adults.
SeoulAges 19 years+ - NCT05767450Recruiting
Test for early type 1 diabetes in children
This study looks at children who have just started insulin for new-onset type 1 diabetes. It aims to test an intervention early in the course of the disease, which may help change how the immune system and diabetes progress.
Milan, MilanAges 7–17 - NCT07610382Recruiting
IV Fluids for Stomach Bugs in Young Children
This study compares two types of IV fluids commonly used to rehydrate young children with gastroenteritis (stomach flu with diarrhea and vomiting). Researchers want to see which fluid works better and causes fewer problems.
AydinAges 6 months–5 years - NCT07608055Recruiting
Pancreas Removal and Metabolic Health in Non-Diabetic Patients
This study follows patients who are having part or all of their pancreas removed due to disease. Researchers want to understand how this surgery affects blood sugar control, weight, and overall health in people without diabetes before surgery.
RomeAges 18 years+ - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07609329Recruiting
Nutritional Support Before Sarcoma Surgery
This study tests whether special nutritional supplements given before surgery for bone or soft tissue sarcoma (a type of cancer) can help your body heal better and recover faster. You'll take oral supplements for at least a week before your planned surgery.
BrnoAges Any age - NCT07606755RecruitingPhase 4
Jinfeng Pill for Hot Flashes and Menopause Symptoms
This study tests whether a traditional Chinese medicine called Jinfeng Pill can reduce hot flashes, night sweats, sleep problems, mood changes, and other symptoms during perimenopause (the transition to menopause, typically ages 45–55). Researchers want to see if this treatment works better than standard options.
Wuhan, HubeiAges 45–55 - NCT07605156Recruiting
New imaging scan for rare adrenal hormone tumors
This study tests a special imaging scan (PET/CT) to help doctors identify adrenal tumors that produce too much of two hormones: aldosterone and cortisol. If you have both hormone imbalances confirmed by blood tests and are planning surgery to remove your adrenal gland, this scan may help your doctors see exactly where the tumor is.
BeijingAges 18–80 - NCT07606014RecruitingPhase 2/Phase 3
Probiotics to Support Mental Health Treatment
This study tests whether taking special probiotics (beneficial bacteria) can help prevent weight gain and metabolic changes when starting antipsychotic medications for psychosis. You'd take probiotics daily while beginning or recently starting one of four common antipsychotic drugs.
Leeuwarden, Provincie FrieslandAges 18–65 - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT07605676RecruitingPhase 4
Acupuncture stimulation versus strength training for anemia from heavy periods
This study tests whether acupuncture-based electrical stimulation or resistance (strength) training can help women with moderate iron-deficiency anemia caused by heavy menstrual bleeding. Both treatments aim to improve energy levels and blood counts alongside standard medical care.
CairoAges 20–30 - NCT07612046Recruiting
MRI of the pancreas for cancer screening
This study uses MRI scans to screen for pancreas cancer in people at high risk due to family history or certain gene mutations. It aims to see if MRI can help find cancer early.
Basking Ridge, New JerseyAges 18 years+ - NCT07607730Recruiting
Group therapy for emotion control in teens with Prader-Willi syndrome
This study tests a group therapy program designed to help teenagers with Prader-Willi syndrome (a genetic condition) learn better emotional control and regulation skills. Your teen and family would attend weekly group sessions to practice tools for managing emotions like anger or frustration.
Kansas City, MissouriAges 13–17 - NCT07611240Recruiting
Comparing two anesthesia types for spine surgery in overweight patients
This study compares two common anesthesia medicines—sevoflurane (inhaled gas) and propofol (IV liquid)—to see which works better for people with obesity having lower-back spine surgery. The goal is to understand which anesthetic is safer and more effective for this group.
ErzurumAges 18–65 - NCT07604493Recruiting
Italian Doctors' Survey on Oral Health and General Wellness
This study asks Italian general practitioners (family doctors) about their views on how oral health—like teeth and gum health—affects overall body health. Your answers help researchers understand what doctors know and think about the connection between mouth and systemic diseases.
Roma, RMAges 18 years+ - NCT07603817Recruiting
Thyroid Disease and Fatty Liver Disease Study
This study looks at the connection between thyroid problems (especially when the thyroid doesn't make enough hormone) and a common liver condition where fat builds up in the liver. Researchers want to understand how these two conditions relate to each other in people without diabetes.
Sohag, Sohag GovernorateAges 18 years+ - NCT07603739Recruiting
Testing Almonds to Help Control Blood Sugar Levels
This study tests whether eating almonds before meals can help control blood sugar in adults with slightly elevated glucose levels. Researchers want to see if this simple dietary change could help prevent or delay type 2 diabetes.
Baton Rouge, LouisianaAges 25–50 - NCT06711211Recruiting
Digestive cancer registry study
This study collects information from patients with different types of digestive cancers to better understand these diseases and improve future care. It does not test a new treatment, but helps doctors learn more about digestive cancers over time.
Madrid, MadridAges 18 years+ - NCT03514589RecruitingPhase 2
Testing a noninvasive Synacthen test in kids and healthy adults
This trial studies how well a short, noninvasive Synacthen test works in people at different ages, including children with asthma. It’s meant to safely measure how the body responds to a hormone signal without needing more invasive testing.
Sheffield, Sheffield (South Yorkshire District)Ages 6 months–60 years - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05254197Recruiting
Brain tumor monitoring study with follow-up brain scans
This study follows people with lower-grade (WHO grade 2 or less) brain tumors using repeat MRI scans over time. It helps doctors understand how these tumors change and which patients may safely delay treatment at first.
SeoulAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,607 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,855 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.