Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07476001RecruitingPhase 2
High-dose testosterone and PSMA-targeted radiation for prostate cancer
This trial tests whether a short course of high-dose testosterone followed by a radioactive drug (PSMA-617) can help men with advanced prostate cancer that has stopped responding to hormone therapy. The goal is to make cancer cells more sensitive to the radiation.
Tampa, FloridaAges 18 years+ - NCT07479498Recruiting
Family weight health program for children 5–12
This trial tests a family-based program to help children ages 5 to 12 who are above a healthy weight. It focuses on increasing physical activity and healthy habits, and includes text messages from your clinic.
Salt Lake City, UtahAges Any age - NCT07474571Recruiting
Study of aging bones and joints using advanced scans
This trial uses scans like X-rays, CT, or MRI to study how bones and joints age. It aims to understand aging-related problems and may help develop better ways to detect or treat them.
BeijingAges 18 years+ - NCT07480265Recruiting
Homocysteine and early heart function in new high blood pressure
This study looks at a substance in your blood called homocysteine and how it affects the early filling of your heart's main pumping chamber. It may help doctors understand heart risks in people newly diagnosed with high blood pressure.
Konya, MeramAges 18 years+ - NCT07472712Recruiting
Fruit and vegetable program for diabetes prevention
This program helps people with prediabetes lower their risk of type 2 diabetes by providing free fruits and vegetables along with cooking classes and support. It takes place over one year at a community location.
Richmond, VirginiaAges 18 years+ - NCT07478653Recruiting
Dental health study for teens with severe obesity
This study looks at whether gum health is linked to heart health in teens with severe obesity. It may help find ways to reduce heart risks by improving dental care.
Lexington, KentuckyAges 12–17 - NCT07480109Recruiting
More protein while on weight-loss meds in women
This study tests if eating extra protein helps middle-aged women with overweight or obesity who are just starting a GLP-1 medication. You would eat extra protein for a few weeks while staying active as usual.
Austin, TexasAges 30–60 - NCT07476859RecruitingPhase 4
Iron for heart attack recovery in older adults
This study tests whether giving iron through a vein can improve quality of life in older adults who recently had a heart attack or unstable angina and also have low iron levels. If you qualify, you would receive either iron or a placebo (inactive substance) to see if iron helps you feel better and recover faster.
El Palmar, MurciaAges 65 years+ - NCT06780410RecruitingPhase 3
Study of bempedoic acid for lowering cholesterol
This trial tests a drug called bempedoic acid to see if it can safely help lower cholesterol in adults. It may be an option if you have high cholesterol and need a different treatment.
BeijingAges 18 years+ - NCT04775381RecruitingPhase 3
Vitamin D before thyroid surgery to prevent low calcium
This study tests whether taking vitamin D (cholecalciferol) before a total thyroid removal can reduce the risk of developing low blood calcium afterward. If you’re having your thyroid removed, the results may help prevent symptoms like tingling, cramps, or spasms caused by low calcium.
AuxerreAges 18 years+ - NCT06560502Recruiting
Testing new treatments for diabetic foot and leg ulcers
This trial tests whether adding a special treatment (cellular acellular and matrix-like products) to standard wound care helps diabetic foot ulcers and venous leg ulcers heal faster. It may be an option if you have a diabetes-related foot ulcer that hasn't healed with standard care.
Circleville, OhioAges 21 years+ - NCT06784557RecruitingPhase 4
Study of ezetimibe's effect on gut bacteria
This trial tests whether ezetimibe, a cholesterol-lowering drug, changes the bacteria in your gut. It may help people with heart disease or high cholesterol who are already on a statin.
SeoulAges 19–80 - NCT06785077Recruiting
Genetic Study in Ovarian Cancer During PARP Inhibitor Therapy
This study looks at the genetic changes in ovarian cancer cells before and during treatment with PARP inhibitors. It aims to understand how these changes may affect treatment response.
MilanAges 18 years+ - NCT06785233Recruiting
Stomach balloon for weight loss in overweight adults
This trial tests a temporary balloon placed in your stomach (the Orbera365 balloon) to help you lose weight. It's for people who are overweight or mildly obese and want a non-surgical option.
Santo André, São PauloAges 18 years+ - NCT06782555RecruitingPhase 1/Phase 2
Study of experimental drug combo for advanced cancers
This trial tests a new combination of three drugs—evofosfamide, zalifrelimab, and balstilimab—in people with advanced prostate, pancreatic, or certain head and neck cancers that have stopped responding to standard treatments.
Houston, TexasAges 18 years+ - NCT05530070Recruiting
Study diet effects on heart risk in celiac disease
This study looks at how celiac disease and gluten-free (GFD) or gluten-containing diets affect blood and cardiovascular (heart and blood vessel) risk factors. It may help researchers understand which diet habits are most important for heart health in people with celiac disease.
Pécs, BaranyaAges 18 years+ - NCT06030388Recruiting
Exercise study for hot flash relief in menopause
This study tests whether strength training or high-intensity aerobic exercise can reduce hot flashes in postmenopausal women. You would exercise 3 times a week for 15 weeks to see if it helps your symptoms.
KalmarAges 45 years+ - NCT06155708Recruiting
Ketone drink study for women with PCOS
This study tests if a special ketone drink can help women with polycystic ovary syndrome (PCOS). Researchers want to see if it improves health markers related to the condition.
Montreal, QuebecAges 18–40 - NCT06573554Recruiting
Comparing two casts for Charcot foot healing
This study compares two ways to take weight off a Charcot foot (a diabetic foot complication) — a special contact cast versus a removable back slab. The goal is to see which method helps your foot heal better.
ChandigarhAges 18 years+ - NCT06645951Recruiting
Italian database study for parathyroid cancer or atypical adenoma
This study is building a database of patients with parathyroid carcinoma or atypical parathyroid adenoma. By gathering information, doctors hope to learn more about these rare tumors and improve care for future patients.
BariAges Any age - NCT06779201Recruiting
Fasting and its effects on metabolism and immunity
This study looks at how fasting affects your body's metabolism and immune system. It may help researchers understand if planned periods of not eating can improve health.
BeijingAges 18–65 - NCT06787911RecruitingPhase 2
Donafenib and immunotherapy before surgery for advanced thyroid cancer
This trial tests a combination of two drugs—donafenib (a targeted therapy) and an immunotherapy (anti-PD-1 antibody)—given before surgery for locally advanced differentiated thyroid cancer. The goal is to shrink the tumor to make surgery easier and more complete. If you have this type of thyroid cancer that is hard to remove completely with surgery alone, this study may be an option.
ShanghaiAges 18–80 - NCT02253251Recruiting
Study genes linked to cancer risk and how they may be affected
This study looks at tiny genetic changes (called microRNA binding site mutations) to understand how they relate to cancer risk, prevention, and treatment. If you (or close family members) have had cancer, and you meet the study’s other requirements, your genetic information could help researchers learn how to better predict and manage cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06392997Recruiting
Saliva test for gynecologic conditions before surgery
This study is testing a simple saliva sample to see if it can help detect gynecologic conditions (like endometriosis, fibroids, or ovarian/uterine/cervical cancer) before or during surgery. If you are having surgery or a biopsy for one of these issues, your saliva may help improve diagnosis.
AngersAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.