Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT07467447RecruitingPhase 2
Testing a weight-loss drug for people with obesity or overweight
This trial tests whether an experimental drug (LY3437943) can help people with obesity or overweight lose weight. It compares the drug to a placebo (inactive shot), and you must be willing to give yourself daily injections.
Shenzhen, GuangdongAges 18–75 - NCT07469800RecruitingPhase 3
IBI362 for high blood pressure in overweight adults
This study tests an injectable medicine (IBI362) to see if it helps lower blood pressure in people who are overweight or have obesity. You may be eligible if you have high blood pressure but are not currently taking medication for it, and you do not have diabetes or major heart problems.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07465224RecruitingPhase 2
Study of ALN-4324 on Insulin Sensitivity in Type 2 Diabetes
This study tests an experimental drug, ALN-4324, to see if it can improve how your body responds to insulin. It’s for adults with type 2 diabetes who are already on certain diabetes medications and have stable blood sugar control.
Chula Vista, CaliforniaAges 18–65 - NCT07465718RecruitingPhase 3
Once-daily trientine for first-line Wilson's disease treatment
This trial tests a once-daily trientine pill as the first treatment for Wilson's disease, a condition where copper builds up in the body. It may help if you've never been treated for Wilson's disease or have only had zinc therapy briefly.
Denver, ColoradoAges 8 years+ - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07470853RecruitingPhase 1
Study of HWK-016 for advanced ovarian or endometrial cancer
This trial tests a new drug called HWK-016, which is designed to target and deliver medicine directly to cancer cells that have a specific marker (MUC16). It is for people with advanced ovarian or endometrial cancer to see if it can shrink tumors or slow their growth.
Little Rock, ArkansasAges 18 years+ - NCT07465263RecruitingPhase 3
Study of SYH2053 Injection for High Cholesterol in HeFH
This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07463846RecruitingPhase 1/Phase 2
Study of ALN-2232 in people with obesity
This trial tests an investigational drug called ALN-2232 in people with obesity to see if it can help with weight management. You may be able to join if you have a BMI between 30 and 40 and do not have diabetes or take other weight-loss or diabetes medications.
Mount RoyalAges 18–65 - NCT06647888Recruiting
Study of Enavogliflozin for Type 2 Diabetes with High Blood Pressure or High Cholesterol
This study looks at how well a medication called Enavogliflozin works for people with type 2 diabetes who also have high blood pressure or high cholesterol. It aims to see if the drug is safe and effective when taken as part of routine care.
SeoulAges 19 years+ - NCT06645899Recruiting
Italian database for parathyroid conditions
This study is creating a database of people with hypoparathyroidism or pseudohypoparathyroidism in Italy. It may help researchers learn more about these conditions and improve future care.
AlessandriaAges Any age - NCT06790329Recruiting
Weight loss trial using stomach stapling and surface ablation
This trial tests a combined procedure that uses stomach stapling (endoscopic sleeve gastroplasty) plus ablation of the stomach lining to help with weight loss. It is for people with obesity who have not been able to lose weight with diet, exercise, or medication alone.
ShatinAges 18–70 - NCT05465616Recruiting
Testing a personalized nutrition program to lower HbA1c
This trial studies whether a personalized nutrition plan from Viome can help lower HbA1c, a blood test that reflects average blood sugar over time. If you’re in the “prediabetes to early diabetes” range, the program may help you improve food choices and possibly lower your HbA1c.
Bothell, WashingtonAges 18 years+ - NCT04932577RecruitingPhase 2/Phase 3
Fecal transplant to treat complications of liver cirrhosis
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
AarhusAges 18–75 - NCT07467460Recruiting
Precision medicine trial for Parkinson's and Alzheimer's
This trial uses advanced tools to better diagnose and treat Parkinson's disease and Alzheimer's disease. It aims to personalize care based on your specific symptoms and biomarkers.
PozzilliAges 18 years+ - NCT07464431RecruitingPhase 4
Sodium bicarbonate for metabolic acidosis and kidney injury
This trial tests if giving sodium bicarbonate helps critically ill patients who have both metabolic acidosis (too much acid in the blood) and acute kidney injury (sudden kidney trouble). It aims to see if this treatment can improve outcomes.
MünsterAges 18 years+ - NCT07467668Recruiting
Iron infusion for heart failure patients with low iron
This trial tests whether giving intravenous iron to adults hospitalized with heart failure and low iron levels helps improve their health. You may be eligible if you have heart failure with reduced pumping function and low iron stores.
Pleasanton, CaliforniaAges 18 years+ - NCT07464015Recruiting
Summer day camps for childhood obesity
This trial is testing whether sending kids to summer day camps can help them manage their weight. It's for children from low-income families who are overweight or obese and see a pediatric doctor.
Orlando, FloridaAges 5–11 - NCT07470593Recruiting
Monitoring glucose to detect early pancreatic islet graft loss
This study uses a continuous glucose monitor (CGM) to watch for early signs that a transplanted pancreatic islet graft may be losing function. The goal is to catch problems sooner and help keep the transplant working well.
StrasbourgAges 18 years+ - NCT07465341Recruiting
Weight navigation program for weight-related health conditions
This study tests a program to help people with obesity and related health conditions like diabetes or high blood pressure lose weight. Participants work with a care team through virtual visits and text check-ins.
Ann Arbor, MichiganAges 18–75 - NCT07463872Recruiting
Managing pancreatic cysts with AI and EUS data
This study uses artificial intelligence to look at EUS images and other information to better understand and manage pancreatic cysts. It aims to help doctors tell different types of cysts apart so they can choose the best treatment for you.
Wuhan, HubeiAges 18 years+ - NCT07463625Recruiting
PET scan for finding ACTH-secreting pituitary tumors
This trial tests a special PET scan using a tracer called FET to locate tiny ACTH-producing pituitary tumors (microadenomas) causing Cushing's disease. It might help guide surgery by identifying exactly where the tumor is in the gland.
BronAges 18 years+ - NCT07463495Recruiting
Testing a supplement called tributyrin for weight and metabolism
This trial tests whether a supplement called tributyrin, which may help with metabolism and weight loss, is safe and effective for people with obesity. You might qualify if you have a BMI between 30 and 45 and are not taking diabetes medications.
Aarhus NAges 18 years+ - NCT07463456Recruiting
Foot temperature test for people with diabetes
This study compares two devices that measure the temperature of the bottom of your feet. The goal is to see if they give the same readings, which could help doctors detect foot problems earlier.
San Cristóbal de La Laguna, Santa Cruz de TenerifeAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.