Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT07477691RecruitingPhase 4
Immune therapy during Palynziq treatment for PKU
This study tests whether combining a drug called methotrexate with Palynziq (a treatment for PKU) can help control immune responses and improve treatment outcomes. It may be an option for adults with PKU who have never used Palynziq or who have not reached target blood levels after at least 24 weeks.
Los Angeles, CaliforniaAges 18–65 - NCT07478497Recruiting
30-day insulin balance health plan
This study tests a 30-day program to improve how your body handles insulin and overall metabolic health. It's for generally healthy adults who can follow the plan and attend study visits.
New York, New YorkAges 18 years+ - NCT07473843RecruitingPhase 3
Study of zodasiran for teens with homozygous familial hypercholesterolemia
This study tests an experimental medicine called zodasiran in teenagers who have a rare inherited condition that causes very high cholesterol. The goal is to see if it can lower cholesterol levels and reduce the risk of heart problems.
St Louis, MissouriAges 12–17 - NCT07473323RecruitingPhase 1
Testing a new drug for healthy adults and those with diabetic kidney disease
This trial tests a new medication called MTX-439. It includes healthy adults and people with diabetic kidney disease to see if the drug is safe and to learn how the body handles it.
Melbourne, VictoriaAges 18–65 - NCT06781775RecruitingPhase 4
Metformin vs insulin for gestational diabetes
This trial compares two medicines—metformin pills and insulin shots—to see which works better for controlling blood sugar in gestational diabetes. You may be able to join if you have gestational diabetes that needs treatment and are willing to take either medicine.
Charlottesville, VirginiaAges 18–50 - NCT06779747Recruiting
Comparing thyroid treatment approaches over time
This study looks back at medical records and follows new patients to understand which thyroid treatments work best for different conditions. It includes people with an underactive or overactive thyroid, thyroid nodules, or thyroid cancer.
Bologna, BolognaAges 18 years+ - NCT06780514Recruiting
Exercise testing for girls with Turner syndrome
This study will have girls with Turner syndrome do a cardiopulmonary exercise test (a special bike or treadmill test) to check how their heart and lungs work during exercise. It may help doctors better understand fitness and health in Turner syndrome.
GhentAges 8–18 - NCT07472712Recruiting
Fruit and vegetable program for diabetes prevention
This program helps people with prediabetes lower their risk of type 2 diabetes by providing free fruits and vegetables along with cooking classes and support. It takes place over one year at a community location.
Richmond, VirginiaAges 18 years+ - NCT07478653Recruiting
Dental health study for teens with severe obesity
This study looks at whether gum health is linked to heart health in teens with severe obesity. It may help find ways to reduce heart risks by improving dental care.
Lexington, KentuckyAges 12–17 - NCT07475780Recruiting
Radiofrequency ablation for recurrent parathyroid cancer
This study tests radiofrequency ablation (a heat-based treatment) for parathyroid cancer that has returned after surgery. It's for people who cannot or choose not to have more surgery, and the tumor can be reached with a needle through the skin.
Houston, TexasAges 18 years+ - NCT07477249Recruiting
Continuous glucose monitor for prediabetes
This trial tests if wearing a continuous glucose monitor can help people with prediabetes understand their blood sugar patterns. You would wear a small sensor on your arm, and the results may help you make changes to prevent diabetes.
Los Angeles, CaliforniaAges 35 years+ - NCT07472686Recruiting
Capsule endoscopy for small bowel in Lynch syndrome
This study looks at how well a tiny camera in a pill (capsule endoscopy) can find early growths or cancer in the small intestine of people with Lynch syndrome. Lynch syndrome increases your risk for certain cancers, and this test might help catch them earlier.
ParisAges 18 years+ - NCT07478172Recruiting
Electrical muscle stimulation exercise for neuromuscular disease
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
Columbia, MissouriAges 18 years+ - NCT07478185Recruiting
Prehab before pancreatic cancer surgery
This trial tests a pre-surgery exercise program (prehab) for people with pancreatic cancer who plan to have chemotherapy first. The goal is to see if getting stronger before surgery helps with recovery.
Worester, MassachusettsAges 18 years+ - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT07477067Recruiting
Exercise and Protein Use in Type 2 Diabetes
This study looks at how exercise and protein work together in people aged 65 and older, either with or without type 2 diabetes. You will be asked to exercise and may receive a protein supplement to see how your body uses protein.
Urbana, IllinoisAges 65 years+ - NCT07478263Recruiting
Healthy eating trial for Latinas to prevent type 2 diabetes
This study tests a behavioral program designed to help Latinas with prediabetes improve their nutrition and eating patterns to prevent type 2 diabetes. It focuses on reducing cravings and building healthy habits.
La Jolla, CaliforniaAges 18–55 - NCT07473713RecruitingPhase 1
Veverimer for bone loss in adults with osteopenia
This study tests whether a medication called veverimer can help reduce bone loss in adults with osteopenia (early bone thinning) by lowering the acid load from their diet. Participants must be 50 or older, eat a typical Western diet, and have low bone density but not full osteoporosis.
Boston, MassachusettsAges 50 years+ - NCT07479134Recruiting
Producing stem cells for pancreatic cell research
This study collects skin or blood samples to create stem cells that can be turned into insulin-producing pancreatic cells. It may help people with diabetes and other beta cell disorders by providing cells for future research or treatments.
MilanAges 12–70 - NCT07480109Recruiting
More protein while on weight-loss meds in women
This study tests if eating extra protein helps middle-aged women with overweight or obesity who are just starting a GLP-1 medication. You would eat extra protein for a few weeks while staying active as usual.
Austin, TexasAges 30–60 - NCT07476222Recruiting
Predicting testosterone decline in middle-aged men
This study looks at why testosterone levels drop in men aged 35-59. It may help identify early signs and ways to prevent it.
AndijanAges 35–59 - NCT07473804Recruiting
Salt loss in newborns: beyond common adrenal issues
This study looks at babies who lose too much salt (hyponatremia) due to hormone problems in the first two months of life. It aims to learn more about conditions other than the common one (21-hydroxylase deficiency).
BolognaAges 1–35 - NCT07480265Recruiting
Homocysteine and early heart function in new high blood pressure
This study looks at a substance in your blood called homocysteine and how it affects the early filling of your heart's main pumping chamber. It may help doctors understand heart risks in people newly diagnosed with high blood pressure.
Konya, MeramAges 18 years+ - NCT07473518Recruiting
Thyroid cancer after childhood radiation therapy
This study looks at thyroid cancer in people who had radiation therapy as children, comparing them to people who did not have radiation. The goal is to see how often thyroid cancer develops after childhood radiation.
BolognaAges 10–43
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.