Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,178 recruiting studies in this area right now.
By phase
- Not applicable2,713
- Phase 2361
- Phase 4321
- Phase 1290
- Phase 3288
- Phase 1/Phase 2141
- Phase 2/Phase 364
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University31
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland146
- Alabama89
- New York76
- Florida74
- Texas61
- Massachusetts56
- Arizona47
- Pennsylvania45
- Illinois42
Recruiting studies4,178 total
- NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90 - NCT03314974RecruitingPhase 2
Stem cell transplant study for blood cancers
This Phase 2 study tests a strong (myeloablative) stem cell transplant using donor stem cells (allogeneic transplant) for certain blood and bone marrow cancers. The goal is to see how well this approach works and whether it can improve outcomes for people who need transplant-level treatment.
Minneapolis, MinnesotaAges Up to 60 years - NCT03035097Recruiting
Study of lung illness for people who served in Southwest Asia
This study is building a research database and stored samples from people who served in the Southwest Asia wars. It may help researchers learn what causes lung problems in veterans and how to better diagnose or treat them.
Denver, ColoradoAges 18 years+ - NCT03375619Recruiting
Long-term follow-up after CAR-T treatment
This study checks in with people who already received CAR-T therapy to learn how they’re doing over time. It may help doctors understand the long-term benefits and side effects of CAR-T for future patients.
Milwaukee, WisconsinAges 18–80 - NCT03258567RecruitingPhase 2
Nivolumab for EBV-related lymphomas and abnormal immune illnesses
This trial tests nivolumab (an immune therapy) for people with EBV-positive lymphoma or EBV-driven immune/lymph conditions. It may help shrink tumors or control the disease when standard treatments have not worked or are not suitable.
Bethesda, MarylandAges 12 years+ - NCT03240328RecruitingPhase 1
CAR-T therapy study for rebuilding HIV immune defenses
This early-stage study tests whether CAR-T cells can help rebuild the immune system’s ability to fight HIV. You may be a candidate if your HIV is well controlled on standard treatment and you don’t have certain serious infections or organ problems.
Guangzhou, GuangdongAges 18–60 - NCT03323112Recruiting
Studying immune responses to seasonal flu shots in health workers
This study looks at how your immune system (your body’s infection-fighting system) responds after you get the seasonal flu vaccine. It may help researchers understand what the vaccine triggers in people working in healthcare and labs.
HelsinkiAges 18–64 - NCT02936232Recruiting
Registry for severe sepsis and septic shock
This registry collects medical information from adults who have suspected or proven serious infection causing body organ problems. It helps researchers better understand what happens in severe sepsis and septic shock and may guide future care.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT03354728RecruitingPhase 1/Phase 2
Vaccine trial for children with CMV after stem cell transplant
This trial studies a vaccine designed to help the body fight cytomegalovirus (CMV) in children who test positive for CMV and are about to receive a donor stem cell transplant. If it works, it may reduce CMV-related illness during recovery after transplant.
Duarte, CaliforniaAges 1–21 - NCT07213973RecruitingPhase 2
Study of povorcitinib for teens with hidradenitis suppurativa
This trial tests an oral medication called povorcitinib for adolescents aged 12–17 with moderate to severe hidradenitis suppurativa (HS) that hasn't improved with standard treatments like antibiotics. It aims to see how well the drug works and if it's safe.
Birmingham, AlabamaAges 12–17 - NCT06481163RecruitingPhase 2
Telacebec treatment for Buruli ulcer in adults
This trial tests whether the drug telacebec can treat Buruli ulcer, a skin infection caused by bacteria. It aims to find a simpler, shorter treatment for people with mild to moderate lesions.
Geelong, VictoriaAges 18 years+ - NCT07245888Recruiting
Studying pneumonia in ventilated ICU patients
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
LimogesAges 18 years+ - NCT07464314RecruitingPhase 1
Testing a combined flu and COVID-19 mRNA vaccine in older adults
This trial is testing whether a new mRNA vaccine that targets both seasonal flu and COVID-19 is safe and creates a strong immune response. It may offer an easier way to protect against two illnesses with one shot.
Anniston, AlabamaAges 65–85 - NCT05661032Recruiting
Testing new ways to identify respiratory viruses
This study tests “new technologies” to identify what virus is causing a respiratory illness, using samples taken from inside your nose. It may help doctors get faster, more accurate answers about the cause of your symptoms.
Portsmouth, HampshireAges Any age - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT07565103RecruitingPhase 1/Phase 2
Testing SUM-191 eye drops for bacterial pink eye
This trial tests a new eye medication called SUM-191 for treating bacterial conjunctivitis (a bacterial infection that causes pink eye). The study has three parts: first testing safety in healthy people, then in people with the infection itself.
Austin, TexasAges 18 years+ - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT02422875Enrolling by invitation
Study of immune markers in autoimmune disease and lupus
This study looks at blood and immune cell markers (autoantibodies and immune cell “signatures”) to better understand autoimmune conditions, including lupus. It may help researchers identify which markers are linked to disease and how immune cells respond after vaccination.
Atlanta, GeorgiaAges 18 years+ - NCT02511002Enrolling by invitation
Long-term follow-up after an influenza challenge study
This study keeps track of how your body’s immune responses change over time after an influenza exposure. Researchers may use stored blood samples to study specific antibody levels, which could help improve future flu vaccines or treatments.
Bethesda, MarylandAges 18–120 - NCT00704626Enrolling by invitation
Blood antibody tests in autoimmune brain and nerve diseases
This study looks at blood “auto-antibodies,” which are immune proteins that may attack the body, in people with certain brain and nerve conditions. It may help researchers better understand these diseases and how the immune system is involved.
Sacramento, CaliforniaAges 18 years+ - NCT02051062Enrolling by invitationPhase 4
Blood-plasma study of botulism antitoxin in children
This trial studies how a botulism antitoxin (called BAT, heptavalent) moves through the body in children. It may help doctors better choose doses and timing for pediatric treatment by learning from blood samples after the first dose.
Ages 1 day–11 years - NCT01933620Enrolling by invitation
NIH study of the microbiome using stored body samples
This study looks at the community of microbes in the body (your “microbiome”) using samples like stool, urine, and possibly tissue. It may help researchers understand how these microbes relate to health in hospital patients.
Bethesda, MarylandAges 2–120 - NCT01374984Enrolling by invitation
Test VIGIV treatment for serious complications from smallpox vaccination
This trial looks at how well a medicine called VIGIV works for people who develop serious or unusual vaccinia (smallpox-type) infections or complications after smallpox vaccination. It is mainly for specific skin and body-area problems, including eczema-related complications.
Ages Any age - NCT00004317RecruitingPhase 4
Treating Congenital Toxoplasmosis With Three Medications
This study tests a combination of three medications (pyrimethamine, sulfadiazine, and leucovorin) to treat toxoplasmosis—a parasitic infection passed from mother to baby during pregnancy. The goal is to see if early treatment prevents serious complications in infected infants.
Chicago, IllinoisAges Any age
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,178 recruiting infectious disease studies from the U.S. registry right now, out of 7,113 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.