Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT04232917RecruitingPhase 4
Testing a treatment to help clear genital high-risk HPV
This trial studies 2LPAPI® to see if it helps the body clear high-risk HPV infections in the cervix. It may be an option if you have a current HPV infection with mild/early abnormal cervical findings and can complete follow-up for about a year.
BrusselsAges 25–45 - NCT04034264Recruiting
Fever Study in Cambodia Using New DNA Testing
This study is looking at people in Cambodia who have a fever or have been in close contact with someone who has a certain infection. Researchers will use a new type of DNA test to try to find the cause of the fever.
Chbar MonAges 2 months+ - NCT04052022Recruiting
Study of TB flare-ups in people without HIV
This study looks at why some people with tuberculosis (TB) get worse or develop new inflammation after they initially start improving on treatment—called a “paradoxical reaction.” It collects blood and tissue samples to better understand these flare-ups and guide future care.
Bethesda, MarylandAges 18–99 - NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04094311RecruitingPhase 3
Testing a modified cell therapy when product quality is off-spec
This study looks at using tisagenlecleucel, a cell therapy, when the final product does not meet routine “commercial release” quality standards. It focuses on whether it can still be given safely and effectively to people with serious or life-threatening illness.
Hamilton, OntarioAges birth–100 years - NCT04065971RecruitingPhase 4
Test drug for frequent cold sores in the mouth
This trial tests whether 2LHERP® can reduce or manage frequent herpes infections around the mouth. It compares the study drug to a placebo (inactive treatment) in people who get many episodes each year.
BeerzelAges 16–80 - NCT04067674Recruiting
Study immune changes in adults with septic shock
This trial looks at how the immune system changes after septic shock in adults in the ICU. It may help doctors better predict or manage complications by studying blood markers a few days after starting treatment.
LyonAges 18 years+ - NCT04098133Recruiting
Tracking germs that resist key antibiotics in Swiss hospitals
This study collects and studies lab-detected germs in hospital patients that produce special enzymes making some antibiotics less effective. It helps researchers understand how these resistant germs spread over time in Switzerland.
BaselAges 18 years+ - NCT04103281Recruiting
Blood test study of immune cell markers in ICU sepsis
This trial looks at patterns in certain immune cells (neutrophils) in people with sepsis in the ICU, including those who have a breathing tube. It may help doctors better understand how the immune system changes during sepsis and could guide future care.
Boston, MassachusettsAges 2–50 - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT04115566Recruiting
HS patient registry and sample storage study
This study enrolls people with hidradenitis suppurativa (HS) to better understand the condition over time and store optional health information and samples. Being in the registry may help researchers learn about patterns in HS and support future research.
San Francisco, CaliforniaAges 10 years+ - NCT04046900RecruitingPhase 1/Phase 2
Fecal-style transplant of vaginal microbiome for recurring BV
This trial tests whether transplanting “good bacteria” into the vagina can treat recurrent bacterial vaginosis (BV). It may help restore a healthier vaginal bacterial balance and reduce BV episodes.
Boston, MassachusettsAges 18–50 - NCT04128189RecruitingPhase 3
Shingrix vaccine for people waiting for a kidney transplant
This Phase 3 study tests whether the shingles vaccine Shingrix is safe and effective for adults with chronic kidney failure who are on the transplant waiting list. It aims to protect you from shingles while you may be dealing with transplant-related immune changes.
Aurora, ColoradoAges 18–70 - NCT03325855Recruiting
Fecal transplant registry for patients and donors
This study is a national “registry” that collects information from people who get fecal microbiota transplant (a stool-based treatment) and from people who donate stool. It helps researchers understand who receives these treatments and how they do over time.
Phoenix, ArizonaAges Any age - NCT03959085RecruitingPhase 3
Inotuzumab plus chemotherapy for high-risk childhood leukemia
This Phase 3 trial tests whether adding inotuzumab to standard post-induction chemotherapy improves outcomes for children and young teens with high-risk B-ALL, mixed phenotype acute leukemia (MPAL), or certain high-risk B-LLy. It may help by targeting leukemia cells more directly, but participation depends on specific age, lab results, and medical history rules.
Birmingham, AlabamaAges 12 months–25 years - NCT03937817Recruiting
Donate samples to study globin gene variants
This study collects common body samples to learn how different globin gene variants work and how they relate to health. Your samples may also be used later for new research, including genetic testing.
Bethesda, MarylandAges 18–70 - NCT03887273RecruitingPhase 1/Phase 2
Cell transplant study for transverse myelitis patients
This trial tests if transplanting special cells into the spine is safe for people with transverse myelitis (a rare spinal cord inflammation) that has caused long-term weakness or trouble walking. It aims to see if these cells can help improve function.
Dallas, TexasAges 18–70 - NCT04006808RecruitingPhase 1/Phase 2
Shingles prevention vaccine study for kids with kidney transplants
This study tests whether an investigational shingles (herpes zoster) vaccine is safe and helps prevent shingles in children who have had a kidney transplant. Because these children take medicines to prevent rejection, the study specifically looks at vaccine effects in this higher-risk group.
BrusselsAges 1–17 - NCT03977753RecruitingPhase 4
Study medicine to treat common, plantar, or flat warts
This trial tests two versions of an at-home medicine to see how well they clear warts. Participants are randomly assigned to the study medicine or a placebo (inactive treatment) so researchers can compare results fairly.
BougeAges 3 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT03933384RecruitingPhase 4
Tenofovir alafenamide versus entecavir for chronic hepatitis B
This study compares two approved hepatitis B medicines—tenofovir alafenamide and entecavir—to see which works best for people with chronic hepatitis B. It may help improve control of the virus and support better long-term liver health.
Taichung, TaichungAges 20 years+ - NCT03945448RecruitingPhase 2/Phase 3
Single-dose antifungal for people with HIV and positive cryptococcal blood test
This study tests whether a one-time antifungal treatment can help people with HIV who have a positive cryptococcal antigen blood test but no symptoms. It may lower the chance that this infection becomes a serious illness affecting the brain.
KampalaAges 15 years+ - NCT03967600Recruiting
Study of hidradenitis suppurativa skin features
This study looks at the physical and biological (body-related) characteristics of hidradenitis suppurativa. It may help researchers understand the condition better and improve future care.
San Francisco, CaliforniaAges 13 years+ - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.