Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,175 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2361
- Phase 4321
- Phase 1292
- Phase 3286
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California237
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,175 total
- NCT04837755Recruiting
Study for COVID-19 and long COVID in Saarland
This study looks at people with current COVID-19 or symptoms lasting after COVID (called long COVID). It aims to learn more about how to care for these conditions and what to expect over time.
Homburg, SaarlandAges birth–110 years - NCT04839757Recruiting
Testing a dengue vaccine plan for kids in the Caribbean
This trial looks at a dengue vaccine strategy in children ages 9 to 17 in Martinique and Guadeloupe. It may help protect kids from dengue, based on how the vaccine is accepted and how the study is carried out.
Fort-de-FranceAges 9–17 - NCT04843111Recruiting
Registry study for pregnancy exposure to MenQuadfi vaccine
This is an observational registry that collects information about pregnant people and their babies when MenQuadfi® (a meningitis vaccine) was given during pregnancy or shortly before pregnancy. It helps researchers understand what happens to women and offspring after this vaccine exposure.
Swiftwater, PennsylvaniaAges Any age - NCT04843852RecruitingPhase 1
Test vaccine added to hepatitis B treatment
This early-phase study tests whether a hepatitis B vaccine (with an added ingredient to boost the immune response) can safely help people with long-term hepatitis B who are already on antiviral therapy. It is mainly looking at safety and how the immune system responds.
Baltimore, MarylandAges 18 years+ - NCT04843982RecruitingPhase 4
Esketamine to reduce inflammation in septic adults
This trial studies whether esketamine can improve the body’s overactive inflammation during sepsis. Participants are adult ICU patients who are sick enough to need breathing support and have higher severity scores.
Wuhan, HubeiAges 18–80 - NCT04844801Recruiting
Prevent fast heart rhythms during sepsis shock with rate control drugs
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
ParisAges 18 years+ - NCT04846803Recruiting
Prevent repeat UTIs using bacterial interference treatments
This trial studies a new way to help stop urinary tract infections (UTIs) from coming back by using “bacterial interference” (changing the bacteria in the urinary system). It may help people who have had UTIs keep returning despite past treatments.
Aarhus NAges 18–90 - NCT04850456Recruiting
Gamma globulin treatment for critically ill children with inflammation surge
This trial studies whether giving “human gamma globulin” can improve outcomes in very sick children in the ICU who have a severe infection causing an extreme inflammation reaction (“inflammatory storm”). If you’re in the hospital ICU with this complication, the study may offer a targeted treatment strategy and careful monitoring.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT04851015RecruitingPhase 3
Low-dose TMP-SMX for Pneumocystis pneumonia (PCP)
This Phase 3 study tests whether low-dose trimethoprim-sulfamethoxazole (also called TMP-SMX) can treat Pneumocystis pneumonia (PCP) in people with weakened immune systems. It may help improve treatment while reducing side effects compared with standard dosing.
Montreal, QuebecAges 18–100 - NCT04853186Recruiting
Cholera vaccine program monitoring and household tracking
This study monitors how cholera vaccination efforts are working in areas where cholera is common. It checks people who come to cholera treatment centers and certain household contacts to see who has cholera and follows them for surveillance.
GomaAges Any age - NCT04855786Recruiting
Drain lymph fluid to reduce inflammation in septic shock
This study tests whether draining fluid from a chest lymph channel can lower inflammation chemicals (cytokines) in people with septic shock. It’s done using a procedure and aims to see if this helps stabilize the body’s inflammatory response.
Philadelphia, PennsylvaniaAges 18–80 - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT04875819RecruitingPhase 4
HIV vaccine safety check for meningitis and pneumonia shots
This trial studies how safe and how well the body’s immune system responds to meningococcal and pneumococcal vaccines in adults living with HIV. It may help confirm these vaccines work properly and are safe for people on HIV treatment.
HvidovreAges 18 years+ - NCT04878549Recruiting
Testing blood-sample patterns to identify the cause of fever
This study looks at changes in blood to figure out what infection is causing a person’s fever (or, for some participants, to compare with people without fever). It may help doctors learn faster ways to identify infections and target the right treatment.
VelloreAges 2–65 - NCT04880200Recruiting
HIV testing at the clinic with help getting care
This study tests point-of-care lab tests that can find HIV-related virus levels quickly, and adds support to help people stay on treatment and connect to prevention services. If you are already HIV-positive and coming in for same-day lab testing, you may be able to get extra help with follow-through.
Seattle, WashingtonAges 18 years+ - NCT04886284RecruitingPhase 2
Cefazolin plus ertapenem for MSSA bloodstream infection
This Phase 2 study tests whether adding ertapenem to cefazolin can improve treatment of staphylococcus (“S. aureus”) bloodstream infection that is likely methicillin-susceptible (MSSA). It aims to start the right antibiotics quickly, before MRSA status is fully confirmed, using early testing and a treatment plan guided by infectious-disease specialists.
Calgary, AlbertaAges 18–100 - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04887623Recruiting
Blood and breathing marker tracking in hospitalized COVID-19
This study follows hospitalized people with recent COVID-19 to see how infection and inflammation markers change over time. It may help doctors better understand what’s happening in the body as breathing problems develop and treatments are given.
Hradec KrálovéAges 18–90 - NCT04896255Recruiting
Long-term follow-up of hepatitis B treatments
This study looks at long-term outcomes in people with chronic hepatitis B who take antiviral medicines or receive interferon. It may help doctors understand which treatments work best over time and who is most likely to benefit.
ShanghaiAges 18 years+ - NCT04896606RecruitingPhase 1/Phase 2
Matched donor immune therapy for mild to moderate COVID-19
This early-phase study tests immune cells from a matched family donor (made to target the COVID-19 virus) to see if they can help people with mild-to-moderate COVID-19 who are hospitalized and at higher risk for getting sicker. It aims to check safety first and also look for signs of benefit.
Valhalla, New YorkAges 18–65 - NCT04897516RecruitingPhase 3
Test whether shorter benznidazole courses work for Chagas
This trial compares a shorter course of benznidazole (a medicine for Chagas disease) to the standard longer treatment. It aims to see if the shorter regimen works as well and is safe for people with confirmed Chagas infection.
Buenos AiresAges 18–60 - NCT04900298Recruiting
Hand hygiene device study during adult surgeries
This study tests whether a personal hand-hygiene system helps reduce germs spreading during surgery. It involves adults having certain types of surgeries and the anesthesia team caring for them.
Portland, OregonAges 18–99 - NCT04902443RecruitingPhase 1
Pomalidomide plus nivolumab for virus-related cancers
This trial studies pomalidomide plus nivolumab in people with cancers linked to certain viruses (or hepatitis B/C). It may help the immune system fight the cancer when the disease has returned, progressed, or can’t be fully treated with standard options.
Bethesda, MarylandAges 18–99 - NCT04906408Recruiting
Testing wound-care steps after ventral hernia surgery
This study looks at whether different post-surgery wound-care steps can reduce problems at the incision site after elective ventral hernia repair. If you qualify, you may receive a specific wound treatment plan chosen by the study team to see how it affects healing and infection rates.
Columbus, OhioAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,175 recruiting infectious disease studies from the U.S. registry right now, out of 7,076 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.