Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,175 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2361
- Phase 4321
- Phase 1292
- Phase 3286
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California237
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,175 total
- NCT05452941Recruiting
Pneumonia vaccine study for hospitalized adults 65 and older
This study tests a pneumococcal vaccine designed for 20 types of bacteria in older adults who are hospitalized with suspected community-acquired pneumonia. It aims to see how the vaccine works in real-world care and whether it affects how pneumonia happens or progresses.
El Centro, CaliforniaAges 65 years+ - NCT05453695RecruitingPhase 1
IV DNase for ICU sepsis with organ stress
This Phase 1 study tests whether an IV medicine called DNase I can safely help people with sepsis who are having worsening organ function. It’s designed to see if the treatment is tolerated and could improve outcomes for ICU patients with early sepsis.
Hamilton, OntarioAges 18–100 - NCT05455034RecruitingPhase 1/Phase 2
Blood and lung-sample test to guide treatment for lung inflammation
This Phase 1/2 study uses detailed “single-cell” testing (from lung samples) to better understand why lung inflammation happens after cancer radiation or immunotherapy. It aims to help choose the right treatment approach for people with radiation pneumonitis or immune checkpoint inhibitor pneumonitis.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT05455359RecruitingPhase 4
Tube-fed children at high risk for aspiration pneumonia
This Phase 4 study looks at gastrointestinal movement (dysmotility) and how it may increase the risk of aspiration pneumonia in children who eat through a tube and have swallowing safety problems. It may help doctors better prevent lung infections in children who cough/choke and need suction often.
Boston, MassachusettsAges 5–21 - NCT05458440Recruiting
Study using immune cells from recovered COVID-19 donors
This study collects immune cells from people who recovered from COVID-19 and may use them to boost protection against SARS-CoV-2. It’s for hospitalized patients who already show a certain level of COVID-19 fighting immune response.
Vandœuvre-lès-Nancy, LorraineAges 18–70 - NCT05459896Recruiting
Health app program for distress, fatigue, pain, and poor sleep
This trial tests whether a smartphone health app can help adults who are struggling with psychological distress (like high stress), physical fatigue, pain, and/or poor sleep after the pandemic. You may qualify if your answers on screening questionnaires show enough distress, and you can use a smartphone and the internet.
Hong KongAges 18–70 - NCT05461651Recruiting
Preventing knee infections after knee replacement
This study looks at ways to lower the risk of infection after knee replacement surgery (with or without vancomycin, an antibiotic). If you’re a good candidate, you may receive an approach aimed at preventing post-surgery infections and related complications.
Otwock, Masovian VoivodeshipAges 40 years+ - NCT05464251Recruiting
Review study for spinal infection diagnosis and outcomes
This study reviews medical records of people with certain spine infections, including infections of the spine bones, the discs, and the space around the spinal cord. It may help doctors better understand these conditions and how they are diagnosed and followed over time.
Lexington, KentuckyAges 18 years+ - NCT05463380Recruiting
Study of hospitalized adults with COVID-19
This study follows adults who are in the hospital (including the emergency ward) with a confirmed COVID-19 infection. It aims to learn how COVID-19 affects people in the hospital and how different cases may differ over time.
DüsseldorfAges 18 years+ - NCT05470023Recruiting
Imaging study of gum health and mouth biofilm
This study uses imaging to look at how healthy your gums are and how much “plaque/biofilm” is in your mouth. It may help researchers better understand gum health and how oral hygiene affects it.
Irvine, CaliforniaAges 18 years+ - NCT05471479RecruitingPhase 4
Activated charcoal for recent poisoning in hospital patients
This pilot study tests giving activated charcoal soon after a poisoning to see if it helps remove certain swallowed toxins. It may be an option if you arrive at the hospital within 6 hours and charcoal is medically safe for you.
Québec, QuebecAges Any age - NCT05471908Recruiting
Compare automatic versus as-needed follow-up after common infections
This study compares two ways of scheduling a check-up after a child is hospitalized: an automatic visit or a visit only if needed (“as-needed”). It may help families and clinicians see which follow-up approach works best after illnesses like pneumonia, stomach flu (gastroenteritis), skin infections, or urinary tract infections.
Phoenix, ArizonaAges Up to 18 years - NCT05471973Recruiting
Study for suspected heart device infection care improvement
This study is testing an approach to improve how clinicians care for people with suspected infections around an implanted heart device (like a pacemaker or defibrillator). It may help ensure the infection is recognized and treated appropriately, especially when device removal (extraction) might be needed.
Chicago, IllinoisAges 18 years+ - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05474430Recruiting
Study testing how common lung infections relate to CF gene status
This study looks at whether carrying one CF gene (being a “CF carrier”) changes the risk of getting respiratory infections. It may help researchers understand how genetics can affect lung health, even for people who do not have cystic fibrosis.
Iowa City, IowaAges 18–100 - NCT05475574Recruiting
Stopping extra cleaning for some resistant bacteria in geriatrics
This trial looks at whether stopping extra “contact precautions” (special measures to prevent spread) is safe for older hospital patients who carry a certain type of hard-to-treat gut bacteria. It may reduce unnecessary isolation and improve comfort, while still aiming to prevent infections.
MetzAges 65 years+ - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT05484128Recruiting
Probiotic for kids taking acid-reducing medicine
This trial studies whether a specific probiotic (Lactobacillus reuteri) is helpful for children who need acid-reducing medicine for reflux or stomach discomfort. It may help improve stomach symptoms while they are on or need treatment with proton pump inhibitors.
BariAges 1–14 - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05488080Recruiting
Improving emergency care for children with appendicitis or fractures
This project looks at how emergency department care is delivered for children with possible appendicitis or a long bone fracture, with a focus on reducing inequities. You may be eligible if your child comes to the emergency department for symptoms that could fit these conditions, and they are not in the most immediately life-threatening category.
Washington D.C., District of ColumbiaAges birth+ - NCT05488340RecruitingPhase 2
Study drug for hard-to-treat bladder infection in women
This Phase 2 trial tests LBP-EC01 to treat a bladder infection (UTI) caused by drug-resistant E. coli. It may help by targeting the specific bacteria that make UTIs harder to cure with common antibiotics.
Fresno, CaliforniaAges 18–75 - NCT05491525RecruitingPhase 2/Phase 3
Vibegron for children with nerve bladder using intermittent catheter
This study tests how well and how safely vibegron works long-term in children (ages 2 to under 18) with a nerve-related bladder condition, who regularly use intermittent catheterization. It also tracks how the body processes the medicine and whether it helps bladder control over time.
Little Rock, ArkansasAges 2–17 - NCT05491941Recruiting
Testing ways to improve care for sepsis patients
This trial looks at how to best put proven sepsis care steps into practice in the emergency department. It may help you or other patients receive faster, more consistent treatment for sepsis.
Providence, Rhode IslandAges 18 years+ - NCT05493267RecruitingPhase 4
Tested immune-cell therapy for drug-resistant tuberculosis
This trial studies an immune-based treatment made from certain T cells (Vγ2Vδ2 T lymphocytes) for multi-drug–resistant tuberculosis (MDR-TB). It may help people whose current drug regimen is not working well or who have limited effective options.
ShanghaiAges 18–65
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,175 recruiting infectious disease studies from the U.S. registry right now, out of 7,076 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.