Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,391 recruiting studies in this area right now.
By phase
- Not applicable2,721
- Phase 2568
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 355
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong35
- Novartis Pharmaceuticals33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California358
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,391 total
- NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT05244486Recruiting
RestoreX traction therapy after prostate surgery
This trial studies whether RestoreX penile traction can help preserve erectile function after a prostatectomy (surgery to remove the prostate), especially when nerves are spared. If you qualify, you may be asked to use the device and be followed over time to see how erections change.
Phoenix, ArizonaAges 18 years+ - NCT05219110Recruiting
More fluids for children sick with toxin E. coli
This study looks at whether giving extra (hyper) fluids early helps children with a high-risk E. coli stomach infection. The goal is to improve outcomes by supporting the kidneys during the illness.
Birmingham, AlabamaAges 9 months–21 years - NCT04580420RecruitingPhase 2
Study of an oxalate-lowering medicine for PH1 and kidney failure
This Phase 2 study tests a medicine called DCR-PHXC to lower body oxalate levels in people with PH1 who have advanced kidney failure. By lowering oxalate, the treatment may reduce harm from oxalate buildup and help researchers understand safety and effectiveness.
San Francisco, CaliforniaAges Any age - NCT04916132Recruiting
Diabetic kidney damage study using urine tests and biopsy
This study looks at how common diabetic kidney damage is in people with type 2 diabetes, and which factors can predict it. If you qualify, you may be asked to have a kidney biopsy to understand what’s happening inside your kidneys.
Skejby, AarhusAges 18–120 - NCT05155033RecruitingPhase 2
A trial of PD-1 plus aldesleukin for melanoma or kidney cancer
This Phase 2 study tests whether combining anti–PD-1 treatment with aldesleukin can shrink or control metastatic melanoma or metastatic kidney (renal cell) cancer. It is mainly for people who have either not had anti–PD-1 before, or whose cancer did not respond to prior anti–PD-1 treatment.
Bethesda, MarylandAges 18–120 - NCT05141487Recruiting
Testing a nerve stimulation trigger for bladder control
This study tests whether a “triggered” nerve stimulation therapy can help people with nerve-related bladder problems hold urine better and empty their bladder more comfortably. It mainly looks at whether the approach is safe and workable for patients.
Cleveland, OhioAges 18 years+ - NCT05183646RecruitingPhase 3
DMX-200 for FSGS in people taking an ARB medicine
This Phase 3 trial studies whether DMX-200 is safer and works better than placebo for people with FSGS who are already on (or can switch to) an ARB blood-pressure/kidney-protection medicine. It also looks at side effects over a long follow-up period.
Birmingham, AlabamaAges 12–80 - NCT05175885Recruiting
Kidney transplant test using machine perfusion outside the body
This study tests a special way to keep and treat a donated kidney using a machine before it’s transplanted. The goal is to improve transplant outcomes for certain people on the kidney transplant waiting list.
Zaragoza, ZaragozaAges 18 years+ - NCT05176483RecruitingPhase 1
New drug combinations for advanced solid tumors
This trial tests a new drug called zanzalintinib, which may slow or shrink various types of advanced cancer. It is given together with other cancer treatments, and the study is looking at many different cancers including kidney, prostate, bladder, lung, liver, and more.
Phoenix, ArizonaAges 18 years+ - NCT05190848Recruiting
Study of gut microbes and blood chemicals in IgA kidney disease
This trial looks at how bacteria in the gut (microbiome) and substances in the body (metabonomics) relate to IgA nephropathy, a kidney condition. The goal is to understand patterns that may help explain the disease and improve future care.
Guangzhou, GuangdongAges 16–65 - NCT05147831Recruiting
Remote arm treatment to prevent kidney injury from contrast dye
This trial tests whether a simple “arm conditioning” technique done remotely before a procedure can help prevent kidney injury caused by contrast dye used during certain heart catheter tests. You might benefit if you’re having a coronary angiogram and your kidney function is reduced, but you’re not on dialysis.
Galveston, TexasAges 18 years+ - NCT05155501Recruiting
Surgery planning approaches for localized prostate cancer
This study compares different approaches used during prostate cancer surgery for men whose cancer is only in the prostate. It may help doctors choose the safest and most effective surgical plan for your situation.
Duarte, CaliforniaAges 40–80 - NCT05160480Enrolling by invitation
Total-body PET scan using FDA-approved tracers for prostate or NET cancer
This pilot study tests a total-body PET scan with approved tracer medicines to help detect cancer spread in people with suspected metastatic prostate cancer or certain neuroendocrine tumors (NETs). You may be able to join if recent scans already suggest metastasis and you can safely complete the scan timing and positioning.
Sacramento, CaliforniaAges 18 years+ - NCT05169892Recruiting
Aquablation treatment study for enlarged prostate in Canada
This trial studies how well Aquablation works for men with an enlarged prostate (BPH) in Canada. You may be eligible if your clinician believes Aquablation is an appropriate treatment and you can complete the study visits and questionnaires.
Toronto, OntarioAges 18 years+ - NCT05161078Enrolling by invitation
Studies CARPEDIEM care for newborns and babies in participating hospitals
This trial looks at how to improve outcomes for newborns and infants who receive CARPEDIEM as part of routine hospital care. It aims to see whether an interdisciplinary team approach can make treatment safer and more effective.
Palo Alto, CaliforniaAges Any age - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05149573Recruiting
PEMF therapy for women with painful bladder symptoms
This trial studies whether a device that uses gentle pulsed electromagnetic waves (PEMF) can reduce symptoms in women with interstitial cystitis/bladder pain syndrome (IC/BPS). It may help if your symptoms are currently fairly severe and ongoing.
Winston-Salem, North CarolinaAges 18–80 - NCT05195515Enrolling by invitation
Study on bladder cancer late effects and quality of life
This study looks at how long-term (late) effects after bladder cancer treatment affect quality of life. You may join if you recently had blood in your urine and are being evaluated for it in a specific region of Denmark.
Aarhus NAges 18 years+ - NCT05188885Recruiting
Chronic kidney disease registry for real-world care
This study collects health information from people with chronic kidney disease (CKD) and also from some people without CKD but with kidney risk factors. It helps doctors understand how CKD develops and how it’s managed in everyday life, not to test a new drug.
Foshan, GuangdongAges 18 years+ - NCT05148156Recruiting
Urolift before radiation to reduce urinary side effects
This study tests whether a procedure called Urolift (which gently opens the prostate to relieve urinary blockage) before radiation therapy (SBRT) can reduce urinary side effects for men who have both prostate cancer and an enlarged prostate. If you qualify, you might experience fewer urinary problems during and after your cancer treatment.
Syosset, New YorkAges 50–99 - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05102110Recruiting
Check rectal mucus in people with throat or lung cancers
This study looks at a substance called rectal mucus during an exam to learn about changes in people with cancers of the throat/airways (aero-digestive tract). It’s a feasibility study, meaning it mainly tests whether this approach is safe and practical.
ExeterAges 18–99 - NCT05106387Recruiting
Study follow-up for people who had a kidney transplant
This study follows adults who previously received vonsetamig in an earlier study and then got a kidney transplant while enrolled. It mainly looks at what happens after the transplant and helps doctors understand outcomes over time.
Los Angeles, CaliforniaAges 18–70
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,391 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,874 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.