Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT07275632RecruitingPhase 1/Phase 2
Testing vonoprazan to prevent delayed kidney function after transplant
This trial tests whether a medicine called vonoprazan fumarate can help prevent delayed kidney function after a first kidney transplant from a deceased donor. It is for people who are ready to follow standard post-transplant care.
ChongqingAges 18 years+ - NCT07275541Recruiting
Platelet test for early kidney rejection diagnosis
This study tests whether a simple blood test that looks at platelet behavior can help doctors diagnose acute rejection after a kidney transplant. Early detection of rejection may lead to faster treatment and better outcomes.
MartinAges 18 years+ - NCT06815107Recruiting
Ureteral double-J stent tolerance study
This study looks at why some people have trouble tolerating a ureteral double-J stent, a small tube placed in the ureter to help urine drain. Researchers will ask about symptoms to find risk factors for poor tolerance, which may help future patients.
AmiensAges 18 years+ - NCT07598214RecruitingPhase 4
Natural supplement to protect kidneys during platinum chemotherapy
This study tests whether a natural supplement made from citrus plant compounds (diosmin and hesperidin) can protect your kidneys from damage caused by platinum-based chemotherapy drugs. Platinum chemotherapy is effective against many cancers but can harm kidney function over time.
Banī SuwayfAges 18–75 - NCT06141798Recruiting
Dialysis Frequency for Older Adults
This trial compares two versus three times weekly dialysis for people aged 60 or older who are just starting maintenance hemodialysis. It aims to find the best schedule for older adults with end stage kidney disease.
Bucheon-siAges 60 years+ - NCT06553469Recruiting
Sacral nerve modulation for bladder and bowel problems after spinal cord injury
This trial tests if sacral nerve modulation can improve bladder and bowel control in people with spinal cord injury. Patients receive a temporary stimulator first, and if it helps, they may get a permanent implant.
Jinan, ShandongAges 18 years+ - NCT07262125Enrolling by invitation
Carbon dioxide pressure and eye nerve sheath in kidney surgery
This study looks at how the carbon dioxide gas used during keyhole kidney cancer surgery affects the pressure behind your eye. The goal is to see if changes in gas pressure influence the nerve sheath that surrounds the optic nerve.
Istanbul, AtaşehirAges 31–69 - NCT06925776Recruiting
Community health workers for kidney disease patients
This trial tests whether a community health worker can help patients with advanced kidney disease get better care and education about home dialysis. The goal is to improve patient involvement and make it easier to navigate social needs.
The Bronx, New YorkAges 18 years+ - NCT07742358Recruiting
Comparing ureteral stent designs in children with kidney stones
This trial compares two types of ureteral stents (small tubes that help urine drain from the kidney to the bladder) in children having surgery for kidney stones. The goal is to see which type causes fewer symptoms like pain or discomfort.
Toronto, OntarioAges 8–18 - NCT06824376Recruiting
Acupuncture for high uric acid without gout
This trial tests if manual acupuncture can safely lower uric acid in people who have high levels but have never had a gout attack. It aims to find a drug-free way to manage hyperuricemia before it causes joint problems.
Wuhan, HubeiAges 18 years+ - NCT06689228Enrolling by invitation
Education and monitoring to improve drug use in dialysis patients
This study tests whether a special education program and remote monitoring can help hemodialysis patients use their medications more safely. It is designed for people who have been on dialysis for at least six months.
Burdur, BucakAges 18 years+ - NCT06879912Recruiting
Study of force feedback tools in robot-assisted surgery
This trial tests new force feedback instruments in the da Vinci 5 robot during surgery. It aims to see if they help surgeons perform procedures more precisely for conditions like cancer or other diseases.
Miami, FloridaAges 22 years+ - NCT07244341RecruitingPhase 1
Valemetostat and darolutamide for advanced prostate cancer
This trial tests a new combination of two drugs (valemetostat and darolutamide) for men with metastatic castration-resistant prostate cancer that has worsened after prior treatment. The goal is to see if the combination can slow cancer growth.
La Jolla, CaliforniaAges 18 years+ - NCT04993859Recruiting
Testing how chemotherapy affects kids’ urinary markers
This study looks at urinary (bladder and urine) measurements in children who previously had cancer and were treated with certain chemotherapy drugs. It may help researchers understand how past chemotherapy can affect bladder function and related health markers over time.
Aurora, ColoradoAges 5–13 - NCT06830798RecruitingPhase 3
Ravulizumab to prevent delayed graft function after kidney transplant
This study tests an investigational medicine (ravulizumab) given through a vein to see if it can prevent delayed graft function—meaning the new kidney takes longer to start working—after a high-risk kidney transplant. It is for adults on dialysis who are getting a kidney from a donor whose heart stopped or who is considered high-risk.
Phoenix, ArizonaAges 18 years+ - NCT07234890RecruitingPhase 2
Testing AV-001 to protect the brain during hemodialysis
This study tests a new medicine called AV-001 to see if it can protect the brain from damage caused by hemodialysis. If you qualify, you may help find a way to reduce thinking and memory problems linked to dialysis.
London, OntarioAges 18 years+ - NCT07741448RecruitingPhase 2
Chemo and targeted drug before surgery for HER2-positive upper tract cancer
This trial tests a combination of chemotherapy (gemcitabine) and a targeted drug (Trastuzumab Rezetecan) before surgery to remove the kidney and ureter. It may help shrink the tumor and improve outcomes for people with HER2-positive upper tract urothelial cancer.
Huanggang, HubeiAges 18–75 - NCT04972669Recruiting
Electrical acupuncture to treat leaks after prostate surgery
This trial studies whether electrical acupuncture can reduce urine leakage (incontinence) after prostatectomy. It is meant for people a few weeks to months after surgery whose cancer markers and symptoms suggest they may be good candidates.
Nanjing, JiangsuAges Up to 75 years - NCT06833463Recruiting
Tacrolimus and diabetes risk in kidney transplant patients
This study looks at how the anti-rejection drug tacrolimus (specifically Envarsus) affects blood sugar and risk of diabetes in kidney transplant patients. It aims to find out which patients might be more likely to develop glucose problems so doctors can adjust treatment early.
GdanskAges 18 years+ - NCT06962410Recruiting
Hybrid Closed-Loop for Diabetes After Kidney Transplant
This trial tests a hybrid closed-loop system (an advanced insulin pump that automatically adjusts insulin) for people with diabetes who have had a kidney transplant. It may help improve blood sugar control and reduce the burden of managing diabetes after transplant.
Taiyuan, ShanxiAges 18–70 - NCT06608953Enrolling by invitation
EECP for artery stiffness in dialysis patients
This study tests whether a non‑invasive treatment called enhanced external counterpulsation (EECP) can help reduce stiffness in the arteries of people on chronic hemodialysis. It may improve heart health and make dialysis more effective.
Bangkok, BangkokAges 18 years+ - NCT07227922RecruitingPhase 1
Study of clofutriben in people with kidney impairment
This study tests how the drug clofutriben is processed in people with moderate kidney impairment compared to those with normal kidneys. It helps determine if dose adjustments are needed in kidney patients.
Orlando, FloridaAges 18–83 - NCT06839404Recruiting
Fluid bolus effect on heart and blood flow
This study looks at how a standard IV fluid bolus affects blood flow and heart function in ICU patients. It aims to better understand the body's response to this common treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT06968494Recruiting
Implantable device to preserve erections after prostate surgery
This trial tests a new implantable device designed to help men keep their erections after nerve-sparing prostate surgery. If you are having surgery for early-stage prostate cancer and have good erectile function now, this device might help you maintain it.
Baltimore, MarylandAges 30–75
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.