Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT05514015RecruitingPhase 4
Rituximab with steroids or rituximab alone for membranous kidney disease
This trial studies how well rituximab works in primary membranous nephropathy (a kidney condition) either by itself or with corticosteroids (steroids). It aims to see which approach controls protein leakage in the urine and protects kidney function.
Guangzhou, GuangdongAges 18–75 - NCT06531499RecruitingPhase 1
Study of a radioactive drug for advanced prostate cancer
This trial tests an extended treatment with a radioactive drug (177Lu-PSMA-617) to see how the body handles it, how safe it is, and how well it works. It is for men with metastatic castration-resistant prostate cancer who have not had chemotherapy yet.
Los Angeles, CaliforniaAges 18–100 - NCT06569056RecruitingPhase 3
HRS-8427 for complicated urinary tract infections
This trial tests a new antibiotic, HRS-8427, for people with complicated urinary tract infections (UTIs) or kidney infections. If you qualify, you would receive the study drug through an IV while in the hospital.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05734794RecruitingPhase 3
Rituximab for new childhood nephrotic syndrome
This trial studies whether rituximab alone can help children with new-onset idiopathic nephrotic syndrome. It compares the treatment approach in order to see if it improves kidney recovery and reduces disease activity.
Hangzhou, ZhejiangAges 2–17 - NCT06533644RecruitingPhase 2
SYNC-T therapy study for advanced prostate cancer
This trial tests a new treatment called SYNC-T Therapy (SV-102) for men with metastatic castration-resistant prostate cancer that has progressed after other treatments. The therapy is given directly into a tumor to help your immune system fight the cancer.
Phoenix, ArizonaAges 18 years+ - NCT04877288RecruitingPhase 3
Switch some teen kidney transplant patients to belatacept
This Phase 3 study tests whether switching teens from one anti-rejection medicine to belatacept works as well as staying on the current regimen. It also looks at safety and whether patients can stay on their anti-rejection medicines.
Birmingham, AlabamaAges 12–17 - NCT07266116RecruitingPhase 1/Phase 2
TQB2934 injection for light chain amyloidosis
This trial tests a new injectable drug called TQB2934 for people with systemic light chain amyloidosis. It aims to see if the drug is safe and effective for those whose disease has come back or gotten worse after previous treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT07208240RecruitingPhase 1/Phase 2
PSMA-targeted radiation before prostate removal for advanced cancer
This trial tests giving a radioactive drug (PSMA-targeted) before surgery for prostate cancer that has spread locally but not to other parts of the body. The goal is to see if it helps lower the risk of the cancer coming back.
Petah TikvaAges 18 years+ - NCT06843538RecruitingPhase 3
Tamsulosin for Easier Urination After Pelvic Floor Surgery
This trial tests whether the drug tamsulosin (a medication that relaxes bladder muscles) helps you urinate more easily right after same-day surgery for pelvic organ prolapse or incontinence. It aims to reduce the need for a catheter after surgery.
Cincinnati, OhioAges 18 years+ - NCT07506980Recruiting
Nurse-led program for dialysis patients to improve self-care
This study tests whether a nurse-led program can help people on dialysis improve their self-care and quality of life. It focuses on those who tend to gain fluid between sessions and may need extra support.
Gokarna, BagmatiAges 18–69 - NCT06738550Enrolling by invitation
Agave inulin for constipation in new dialysis patients
This study tests whether a natural fiber supplement called agave inulin can help with constipation and improve quality of life for people who have just started peritoneal dialysis for kidney failure.
Metepec, State of MexicoAges 18 years+ - NCT06847139Recruiting
Zinc vs. folic acid for high homocysteine in kidney dialysis
This trial tests whether zinc supplements can lower high homocysteine levels better than folic acid in people with chronic kidney disease who are on hemodialysis. It aims to find a simple, safe way to help protect your heart and blood vessels.
ChittagongAges Any age - NCT07548853RecruitingPhase 3
Testing TS-172 to Lower Phosphorus in Peritoneal Dialysis Patients
This study tests whether a new medicine called TS-172 can help lower phosphorus levels in patients on peritoneal dialysis (a type of kidney treatment). High phosphorus can cause bone problems and other complications, so the trial aims to see if this drug works better than current treatments.
TokyoAges 18 years+ - NCT06802497Recruiting
Comparing two less invasive surgeries for pelvic organ prolapse
This trial compares two minimally invasive surgical techniques (laparoscopic lateral suspension and V-NOTES lateral suspension using the Salman Ketenci Gencer method) to repair severe pelvic organ prolapse. It aims to see which approach leads to better recovery and outcomes for patients who are sexually active.
IstanbulAges 18–75 - NCT06288425Enrolling by invitation
Gene activity study in kidney transplant patients
This study looks at gene activity inside kidney tissue to better understand how transplanted kidneys work. Researchers will collect blood, urine, stool, and tiny pieces of kidney tissue over time to see what happens after a transplant.
Westmead, New South WalesAges 18–75 - NCT07187180Recruiting
Comparing two laser surgeries for enlarged prostate
This trial compares two types of laser surgery (Thulio and Holmium) for treating an enlarged prostate (benign prostatic hyperplasia). It aims to see which laser works better and is safer, so you may get a more effective procedure with fewer side effects.
Cleveland, OhioAges 18 years+ - NCT07362355RecruitingPhase 2
New gout pill combined with febuxostat for high uric acid
This trial tests an experimental tablet (SHR4640) added to the standard gout medicine febuxostat (40 mg daily) for people whose uric acid remains too high despite febuxostat alone. The goal is to see if the combination lowers uric acid more effectively and safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07182942RecruitingPhase 4
Study of Xiqing and Probiotics for Chronic Kidney Disease
This trial tests if taking Xiqing (a Chinese herbal product) and probiotics together can help people with chronic kidney disease (CKD) by improving gut health and making their medication work better. It is for patients with moderate to advanced CKD who do not need dialysis yet.
Wuhan, HubeiAges 18–75 - NCT07181174Enrolling by invitation
Early prediction of kidney injury after hemorrhagic stroke
This study looks for early signs of kidney injury in people who have had a spontaneous hemorrhagic stroke. It aims to detect kidney problems quickly so they can be treated sooner.
AswānAges 18 years+ - NCT07174349RecruitingPhase 4
Medication to prevent urine retention after spine surgery
This trial tests whether a medication called tamsulosin can prevent or shorten the time you need a urinary catheter after spine surgery. It is for people having specific types of neck or lower back surgery.
Rochester, MinnesotaAges 35 years+ - NCT06848868RecruitingPhase 1
Clinic-based scope for bladder cancer follow-up
This trial tests if a procedure done in the clinic, without general anesthesia, can safely check the upper urinary tract after kidney-sparing surgery for urothelial cancer. It may reduce the need for hospital visits.
Hong KongAges 18 years+ - NCT06414759RecruitingPhase 4
Combination diuretic therapy for heart failure fluid overload
This trial tests a combination of water pills (diuretics) to help remove extra fluid in people hospitalized with acute decompensated heart failure (sudden worsening of heart failure). It aims to find a safe and effective way to reduce swelling and fluid buildup.
Giza, GZAges 18–65 - NCT04731961Recruiting
Fewer Botox shots for urgency bladder leakage
This trial tests whether you can get fewer Botox injections to control urgency urinary incontinence (sudden, hard-to-hold urine leaks). It may help people reduce how often they need bladder injections while still improving symptoms.
Charlottesville, VirginiaAges 21 years+ - NCT07162779Enrolling by invitation
New PET scan for advanced prostate cancer patients
This trial tests a new type of PET scan using a radioactive tracer called [68Ga]DOTA-IR-780-C-4 to see if it can find prostate cancer cells that express a protein called PSMA. If you have advanced prostate cancer that has stopped responding to standard treatments, this scan may help your doctor better understand your cancer and possibly guide future care.
Wuxi, JiangsuAges 18–80
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.