Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,505 recruiting studies in this area right now.
By phase
- Not applicable2,822
- Phase 2562
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4195
- Phase 2/Phase 359
Top conditions
- Prostate Cancer651
- Bladder Cancer192
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer105
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer56
- Lupus Nephritis53
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong34
- Novartis Pharmaceuticals34
- AstraZeneca29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama111
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,505 total
- NCT05159466Recruiting
Transplant from HIV-positive donors to HIV-positive recipients
This trial studies whether it’s safe and effective for HIV-positive people to receive organ transplants from HIV-positive donors. It focuses on matching HIV treatment before and after transplant and checking for major complications.
Metairie, LouisianaAges 18 years+ - NCT05163197Recruiting
Registry for laser treatment of localized prostate cancer
This is a registry study that collects information from men with localized prostate cancer who receive transperineal laser ablation (a procedure done through the skin between the scrotum and anus). It may help doctors better understand outcomes and refine treatment choices over time.
AmsterdamAges 18 years+ - NCT05169112RecruitingPhase 3
Hormone therapy to prevent prostate cancer coming back
This trial studies whether hormone therapy (also called ADT) after prostate surgery lowers the chance that prostate cancer will return. It targets people with very low PSA after surgery but with a higher predicted risk of recurrence.
Halifax, Nova ScotiaAges 18 years+ - NCT05168618RecruitingPhase 2
Cabozantinib and atezolizumab for advanced prostate cancer
This Phase 2 trial tests cabozantinib plus atezolizumab in people with metastatic prostate cancer that keeps growing despite hormone-blocking therapy and newer hormone drugs. It may help shrink tumors and control the disease, especially in advanced cases where options are limited.
Salt Lake City, UtahAges 18 years+ - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05183646RecruitingPhase 3
DMX-200 for FSGS in people taking an ARB medicine
This Phase 3 trial studies whether DMX-200 is safer and works better than placebo for people with FSGS who are already on (or can switch to) an ARB blood-pressure/kidney-protection medicine. It also looks at side effects over a long follow-up period.
Birmingham, AlabamaAges 12–80 - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05188885Recruiting
Chronic kidney disease registry for real-world care
This study collects health information from people with chronic kidney disease (CKD) and also from some people without CKD but with kidney risk factors. It helps doctors understand how CKD develops and how it’s managed in everyday life, not to test a new drug.
Foshan, GuangdongAges 18 years+ - NCT05190848Recruiting
Study of gut microbes and blood chemicals in IgA kidney disease
This trial looks at how bacteria in the gut (microbiome) and substances in the body (metabonomics) relate to IgA nephropathy, a kidney condition. The goal is to understand patterns that may help explain the disease and improve future care.
Guangzhou, GuangdongAges 16–65 - NCT05191680RecruitingPhase 2
Testing apalutamide in early prostate cancer active surveillance
This Phase 2 trial tests whether apalutamide can help people with early prostate cancer who choose active surveillance. It uses MRI and biopsy results to confirm the cancer type and location, then checks if treatment is safe and potentially helpful.
Cambridge, CambridgeshireAges 18 years+ - NCT05194137Recruiting
Training pelvic floor muscle with biofeedback or exam guidance
This study compares two ways to help women learn how to tighten the pelvic floor muscles. It may help women with pelvic floor problems and urinary leaking by improving muscle control using either biofeedback or clinician guidance.
Ribeirão Preto, São PauloAges 18 years+ - NCT05204108Recruiting
Ultrasound test to check bladder cancer muscle spread
This trial studies a special ultrasound scan with contrast dye to see whether bladder cancer has grown into the muscle layer. It may help doctors plan the best treatment before surgery.
Guangzhou, GuangdongAges 18–75 - NCT05200923Recruiting
Testing a pelvic nerve device study for bladder and bowel leaks
This study checks how well an implanted pelvic nerve system works for people with bladder overactivity, non-obstructive urinary retention, or fecal incontinence. You may need to keep your current medications steady and track symptoms closely with diaries before and during evaluation.
Indianapolis, IndianaAges 18 years+ - NCT05201469RecruitingPhase 2
VIB4920 for lupus kidney inflammation not responding well enough
This Phase 2 study tests VIB4920 to treat active lupus nephritis, a type of kidney disease caused by lupus. It may help reduce kidney inflammation and improve kidney outcomes in people with active disease despite standard care.
La Jolla, CaliforniaAges 18 years+ - NCT05204186Recruiting
AI Tool to Predict Health Outcomes After Bladder Removal Surgery
This study tests an artificial intelligence tool designed to predict how patients will recover after bladder cancer surgery. The AI analyzes existing medical information to help doctors better understand which patients might face complications based on their other health conditions.
Amiens, PicardieAges 18 years+ - NCT05206500RecruitingPhase 4
Test whether urine genetic testing changes care
This study looks at whether next-generation DNA testing from your urine can help doctors make better decisions about your treatment. You may be asked to return for follow-up visits so researchers can compare outcomes over time.
Winston-Salem, North CarolinaAges 18–80 - NCT05207358RecruitingPhase 4
Lower steroid use in active lupus kidney inflammation
This trial looks at whether people with proliferative lupus nephritis can use less steroid medicine while still controlling kidney inflammation. It may help reduce steroid side effects, while testing a carefully monitored treatment plan.
BucharestAges 18–80 - NCT05209243Recruiting
Treating limited-spread prostate cancer with radiation plus hormone therapy
This trial studies whether adding focused radiation (SBRT) to hormone therapy can control prostate cancer that has spread to only a few places. It aims to help people with early “oligometastatic” prostate cancer by improving disease control while limiting treatment side effects.
MadridAges Any age - NCT05214885Recruiting
Study biomarkers in kidney cancer and healthy people
This study looks at blood or body measures called “biomarkers” to understand how lack of oxygen and body energy changes in clear cell kidney cancer. It compares people with kidney cancer to carefully matched healthy volunteers to see what patterns might help improve understanding or future care.
JinanAges Any age - NCT05214937Recruiting
Help to reduce sitting time in prostate cancer survivors
This study tests an intervention to help prostate cancer survivors sit less and move more. It may help improve daily activity and reduce long periods of inactivity.
Toronto, OntarioAges 18 years+ - NCT05218811Recruiting
Cryo treatment with partial kidney surgery for kidney tumors
This study looks at using a cold (cryoablation) treatment along with partial kidney surgery to treat certain kidney tumors. It may help shrink or control the tumor while preserving more healthy kidney tissue.
Miami Lakes, FloridaAges 55–65 - NCT05219110Recruiting
More fluids for children sick with toxin E. coli
This study looks at whether giving extra (hyper) fluids early helps children with a high-risk E. coli stomach infection. The goal is to improve outcomes by supporting the kidneys during the illness.
Birmingham, AlabamaAges 9 months–21 years - NCT05223803RecruitingPhase 2
Study radiation for early metastatic prostate cancer
This Phase 2 trial tests a radiation-focused approach for people with newly diagnosed (de novo) prostate cancer that has spread to a small number of spots, especially in bone. It aims to see how well the treatment controls the cancer while keeping side effects manageable.
La Jolla, CaliforniaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,505 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,180 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.