Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,630 recruiting studies in this area right now.
By phase
- Not applicable4,302
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4207
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois71
Recruiting studies6,630 total
- NCT05589753RecruitingPhase 1/Phase 2
Testing treatment for sleep breathing problems in people on opioids
This trial studies a treatment approach for sleep-disordered breathing (breathing problems during sleep) in Veterans who take prescription opioids. It may help doctors learn safer ways to manage sleep breathing issues that can be made worse by opioid use.
Detroit, MichiganAges 18–89 - NCT05590130Recruiting
Test two oxygen targets using different oxygen monitors
This study compares how much oxygen is needed and how well oxygen levels stay in a safe range after heart surgery in the ICU. It also tests whether using different oxygen monitors affects oxygen flow and oxygenation.
Québec, QuebecAges 18 years+ - NCT05589818RecruitingPhase 2
Pembrolizumab for advanced lung cancer without key gene targets
This Phase 2 trial studies pembrolizumab (an immunotherapy drug) in people with advanced non-small cell lung cancer whose disease can’t be treated with curative surgery or combined chemoradiation. It aims to see how well the treatment works and how safely it can be given, especially for people who have not had other cancer medicines for metastatic disease.
New York, New YorkAges 18 years+ - NCT05591118RecruitingPhase 3
Catheter treatment to remove blood clots in the lungs
This Phase 3 trial tests a catheter-based procedure to remove a lung blood clot (pulmonary embolism) and reduce strain on the heart. It may help people who have specific CT scan signs of right-heart strain.
Birmingham, AlabamaAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05596578Recruiting
Study of lymph nodes during lung surgery for early lung cancer
This study looks at certain lymph nodes removed during surgery for non-small cell lung cancer (NSCLC) that has grown into the covering of the lung. The goal is to better understand lymph node involvement and help guide future treatment decisions.
LucerneAges 18 years+ - NCT05596786RecruitingPhase 3
Rituximab for worsening inflammatory lung scarring
This trial studies whether rituximab can slow worsening lung scarring (interstitial lung disease) when there is an inflammatory component. You would get rituximab or a placebo (inactive treatment) in a blinded, randomized design to compare safety and effectiveness.
ToursAges 18–100 - NCT05598528Recruiting
Study why some lung cancers don’t respond to EGFR pills
This study looks at why certain EGFR-positive advanced lung cancers resist third-generation EGFR tablet treatment given as the first treatment. Your body samples and scan results help researchers understand the resistance, which may guide better future care.
Changsha, HunanAges 18 years+ - NCT05600569Recruiting
Thoracic surgery registry study in Spain
This is a registry (a secure log) that collects information about patients who undergo thoracic (chest) surgery. It helps researchers understand what surgeries are being done and may improve planning and care over time.
ZaragozaAges Any age - NCT05607888Recruiting
Study of treatment for sinus and skull-base tumors
This study looks at how doctors manage tumors that start in the nose/sinuses and spread to the skull base. It may help improve planning of care for people with this specific type and location of tumor.
Ljubljana, LjubljanaAges Any age - NCT05608668Recruiting
Breathing and activity coaching for kids with obesity and mild asthma
This trial tests an “inspiratory pulmonary rehabilitation” program—guided breathing and exercise training—for children who have obesity and mild asthma. It may help improve breathing control and exercise ability by teaching safe, structured breathing and activity habits.
Durham, North CarolinaAges 8–17 - NCT05610436Recruiting
Long COVID patients: tracking symptoms and outcomes over time
This study follows people who have ongoing symptoms after COVID (“post-Covid condition”) to better understand how symptoms change and what factors affect recovery. It may help improve care for patients seen at a Long COVID support clinic.
Vandœuvre-lès-Nancy, Grand EstAges 18 years+ - NCT05610631Recruiting
Switzerland heart-lung pressure registry for people with PH
This is a registry that collects information from people who have pulmonary hypertension (high blood pressure in the lungs). It helps researchers better understand the condition and may support future studies.
ZurichAges Any age - NCT05611268Recruiting
Pentoxifylline added for Eisenmenger syndrome
This study tests whether adding pentoxifylline to usual care can improve health outcomes in people with Eisenmenger syndrome. It may help reduce problems related to blood flow and vessel function, especially for those not recently hospitalized.
São PauloAges 10–80 - NCT05612256Recruiting
Measuring breathing pressure in newborns using EIT
This study uses a painless electrical sensor method (EIT) to help find the best positive end-expiratory pressure setting for newborns on a ventilator. The goal is to improve how the ventilator supports breathing in the early days of life.
BaselAges birth–4 weeks - NCT05612594RecruitingPhase 4
Study of an SGLT2 pill for sleep apnea in overweight adults
This study tests whether taking an SGLT2 inhibitor pill (bexagliflozin) can improve obstructive sleep apnea and related body measurements. It focuses on people who are overweight or obese and have confirmed obstructive sleep apnea.
New Haven, ConnecticutAges 18 years+ - NCT05613452RecruitingPhase 2
Carbon ion radiation for peripheral lung cancer you can’t operate on
This trial tests whether carbon ion radiation (high-energy targeted radiation) can control peripheral non-small cell lung cancer in people who are medically unable to have surgery. It may help shrink or stop tumor growth while limiting harm to nearby organs.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05614375Recruiting
Endoscopic surgery for soft tissue cancer in the nose
This trial studies using a minimally invasive camera-assisted surgery to remove soft tissue sarcoma in the nose and nearby sinuses. It may help by aiming to fully remove the tumor safely while considering how well patients’ bodies can handle surgery.
Shanghai, Shanghai MunicipalityAges Any age - NCT05616546RecruitingPhase 4
Study of immune responses during and after flu infection
This study looks at how your immune system (your body’s infection-fighting system) responds during and around the time of a flu illness. It’s meant to help researchers better understand immune changes in healthy adults and may guide future flu care.
Atlanta, GeorgiaAges 18–64 - NCT05620329Recruiting
Pleural fluid registry for drainage in adults
This registry collects information from adults who have fluid around the lungs (pleural effusion) and need clinically indicated drainage because of infection or cancer. It helps researchers better understand these conditions and improve future care.
Chapel Hill, North CarolinaAges 18 years+ - NCT05620342RecruitingEarly Phase 1
CAR T-cell therapy for GD2-positive lung cancer
This early-phase study tests a customized immune-cell treatment (CAR T cells) that targets a protein called GD2 on lung cancer cells. It may help people with certain lung cancers that did not respond to platinum chemotherapy and who have also had treatment that blocks PD-1/PD-L1.
Chapel Hill, North CarolinaAges 18 years+ - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT05623956Recruiting
Proteomics study in newly diagnosed small cell lung cancer
This study uses a lab test called “proteomics” to learn more about newly diagnosed small cell lung cancer (SCLC). It may help researchers understand the disease better and improve future treatment decisions, while participants also receive standard chemotherapy.
Aalborg, Region North JutlandAges 18 years+ - NCT05624996RecruitingPhase 3
Targeted high-dose radiation added to standard lung cancer treatment
This trial tests whether adding high-dose, targeted radiation to the usual treatment helps people with locally advanced, non-operable lung cancer live longer or better control the cancer. It may help shrink tumors in the chest and improve outcomes when surgery can’t be done.
Birmingham, AlabamaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,630 recruiting pulmonology studies from the U.S. registry right now, out of 10,612 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.