Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT07145632Recruiting
Smartphone app to improve inhaler technique for asthma and copd
This study tests a smartphone app that helps you learn or improve how to use your inhaler correctly. The app provides education and training to make sure you get the most from your medication.
Uppsala, Uppsala CountyAges 16 years+ - NCT07154355Recruiting
Community exercise for heart and lung patients
This study tests whether a community exercise program can improve health in people with heart or lung problems. It may help if you are not already doing regular, structured exercise.
Guangzhou, GuangdongAges 18–85 - NCT07149233Enrolling by invitation
Breathing muscle training for sleep apnea patients
This trial tests whether training the muscles you use to breathe can improve sleep for people with moderate to severe obstructive sleep apnea. It is for adults who are not currently receiving standard treatments like CPAP.
Recife, PernambucoAges 18–70 - NCT07153445RecruitingPhase 2
Atezolizumab before and after surgery for stage III lung cancer
This trial tests whether the immunotherapy drug atezolizumab, given before and after surgery, can help treat stage III non-small cell lung cancer that has not spread to other parts of the body. It is for people who have not had any previous cancer treatment for this disease.
Alicante, AlicanteAges 18 years+ - NCT07153263Recruiting
Testing a new numbing shot for lung nodule localization
This study tests a new type of numbing injection (called a retro-superior costotransverse ligament space block) to see how well it spreads and numbs the area during CT-guided lung nodule localization. The goal is to find better ways to keep you comfortable during the procedure.
Nanjing, JiangsuAges 18–80 - NCT07152834Recruiting
Screening for Alpha-1 Antitrypsin Deficiency in Lung Blockage
This study screens for a rare genetic condition called Alpha-1 Antitrypsin Deficiency in people with lung blockage. It aims to find out if this deficiency is a hidden cause of your breathing problems, which could lead to better treatment options.
Muğla, MenteşeAges 18 years+ - NCT07151898Recruiting
PET/CT scan to see if a new drug is working in advanced lung cancer
This trial tests whether a special PET/CT scan can show how well a Trop2-targeting drug is working in people with advanced lung cancer that has already been treated. It aims to improve how we monitor treatment response.
Xiamen, FujianAges 18 years+ - NCT07149935Recruiting
Exercise training for pulmonary arterial hypertension
This study tests whether a special exercise training program can help people with pulmonary arterial hypertension (PAH) feel better and stay stable. If you have mild-to-moderate PAH and are on stable medication, you may be able to join.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07150923Recruiting
Supraglottic airway for newborn breathing support
This study tests whether a special breathing tube placed above the voice box (called a supraglottic airway) works better than the usual mask or tube to help newborns who need breathing support right after birth. It is for babies born at or after 34 weeks of pregnancy.
Birmingham, AlabamaAges birth+ - NCT07149649RecruitingPhase 2/Phase 3
Magnesium for advanced lung cancer
This trial tests if adding magnesium supplements to standard first-line treatment (chemotherapy plus immunotherapy) improves outcomes for people with advanced non-small cell lung cancer (NSCLC) that has spread or cannot be removed by surgery. It is for patients who have not had prior treatment for metastatic disease.
AarauAges 18 years+ - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months - NCT07147517Recruiting
Tracking respiratory viruses in your community and home
This study tracks how respiratory viruses spread in the community and within households. It involves testing and collecting samples from people who are sick or healthy, to help better understand and prevent outbreaks.
La Jolla, CaliforniaAges Any age - NCT04515836RecruitingPhase 2
Olaparib for HRD malignant mesothelioma after platinum chemotherapy
This trial tests whether olaparib (a cancer medicine) can help control malignant mesothelioma that has specific DNA changes. You must have already had platinum chemotherapy and your cancer must be “platinum-sensitive,” plus your tumor (or family/genetic cells) must show certain gene problems.
Chicago, IllinoisAges 18 years+ - NCT06404892Recruiting
Predicting Lung Problems After Chest Surgery
This study is looking at how well certain risk scores predict lung problems after chest surgery. It involves patients who will have surgery using one-lung breathing, and the goal is to learn which scores are most useful.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06401824RecruitingPhase 2
Combination drug therapy for lung cancer with brain spread
This trial tests a combination of two drugs, sacituzumab govitecan and bevacizumab, for people with a specific type of lung cancer (non-squamous) that has spread to the brain. It aims to see if this treatment can shrink brain tumors and improve outcomes.
AmsterdamAges 18 years+ - NCT06474039RecruitingPhase 3
COPD treatment: triple vs. double inhaler for air trapping
This trial tests whether adding a third medicine (fluticasone furoate/vilanterol/umeclidinium) to a two-medicine inhaler (vilanterol/umeclidinium) can reduce air trapping and inflammation in the lungs and blood of people with COPD GOLD B. It may help you breathe better and have fewer symptoms.
Bangkoknoi, BKKAges 40–80 - NCT06953414Recruiting
Predicting difficult awake breathing tube placement
This study tests a way to predict which patients will have a hard time placing a breathing tube while they are awake, using a flexible scope. It aims to help doctors plan safer procedures for people with known difficult airways.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06959173Recruiting
Personalized treatment for fluid around the lungs
This study uses lab-grown miniature versions of your cancer cells (organoids) to find which treatment might work best for you. It's for people with fluid around the lungs caused by cancer (malignant pleural effusion).
Zhengzhou, HenanAges 18 years+ - NCT04891237RecruitingPhase 3
Grass and olive allergy vaccine trial for teens to older adults
This Phase 3 trial tests whether an allergy treatment can reduce symptoms caused by grass and olive pollen. It also checks safety, especially for breathing and allergic reactions, in people with confirmed grass/olive allergy.
Tarancón, CuencaAges 12–65 - NCT05009758Recruiting
Asthma and nasal polyps study to match immune patterns
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
ViennaAges 18–99 - NCT06462417Recruiting
Testing arbidol for allergic rhinitis
This trial tests if arbidol, an antiviral medicine, can safely treat allergic rhinitis (hay fever). It might help if your nasal symptoms like sneezing or stuffiness are moderate to severe.
Wuhan, HubeiAges 18–65 - NCT05892614RecruitingPhase 2
Efzofitimod for early systemic sclerosis lung scarring
This trial tests efzofitimod to see if it can improve or slow lung disease caused by systemic sclerosis (scleroderma), and to check safety and side effects. It focuses on people with relatively early disease and measurable lung involvement on lung scans.
Los Angeles, CaliforniaAges 18 years+ - NCT07144280RecruitingPhase 3
Study of a new drug vs docetaxel for advanced lung cancer
This trial tests a new experimental drug called PF-08046054/SGN-PDL1V against a standard chemotherapy (docetaxel) for people with a type of advanced lung cancer that has PD-L1 protein on at least 1% of tumor cells and has progressed after prior treatments. The goal is to see if the new drug works better or has fewer side effects.
Alabaster, AlabamaAges 18 years+ - NCT07143448RecruitingPhase 1/Phase 2
Study of HS235 for pulmonary arterial hypertension in adults
This trial tests an experimental drug called HS235 for people with pulmonary arterial hypertension (PAH), a condition of high blood pressure in the lungs. It aims to see if the drug can help improve symptoms and exercise ability.
Tampa, FloridaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.