Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06865339RecruitingPhase 2
Radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding two immunotherapy drugs (cemiplimab and fianlimab) to standard radiation and chemotherapy can help treat locally advanced non-small cell lung cancer that hasn't been treated before.
The Bronx, New YorkAges 18 years+ - NCT06860542RecruitingPhase 2
Inhaled steroid to prevent lung inflammation from returning after immunotherapy
This trial tests whether using an inhaled steroid (budesonide) can help prevent lung inflammation (pneumonitis) from coming back in people who have had it caused by immunotherapy cancer treatment. It may be an option for patients who need extra support after their first bout of this side effect.
Calgary, AlbertaAges 18 years+ - NCT06866652Recruiting
Why Am I Short of Breath? A Study in Myasthenia Gravis
This study looks at why people with myasthenia gravis (MG) feel short of breath. It aims to understand breathing problems that happen in daily life, even when MG seems stable.
ParisAges 18 years+ - NCT06864624RecruitingPhase 2
Perioperative sunvozertinib for stage II-IIIB NSCLC with EGFR exon 20 insertion
This trial tests the drug sunvozertinib before and after surgery for non-small cell lung cancer that has a specific EGFR mutation (exon 20 insertion). It aims to see if the drug can help shrink tumors and improve outcomes for patients whose cancer is at stage II, IIIA, or IIIB.
Changsha, HunanAges 18 years+ - NCT06861543RecruitingPhase 1
TMT101 for advanced pancreatic or lung cancer
This trial tests a new drug called TMT101 for people with advanced pancreatic cancer or non-small cell lung cancer who have already tried other treatments. The goal is to see if TMT101 is safe and works against the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT06861686Recruiting
New classification for obstructive sleep apnea
This study is improving how doctors classify obstructive sleep apnea (a condition where your breathing stops and starts during sleep). It focuses on sleepiness and heart-related risks to help guide treatment. If you are 40 or older and have untreated OSA, you may be able to join.
Antwerp, AntwerpAges 40 years+ - NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06547463Recruiting
Nasal airflow and sleep in tracheostomy patients
This study looks at how breathing through your nose affects sleep quality for patients with a tracheostomy who are on a ventilator at night. It involves a sleep test to measure your sleep patterns and breathing, which could help improve your care.
Paris, ParisAges 18 years+ - NCT06790082RecruitingPhase 2
FAPI PET scan to diagnose pleural mesothelioma
This trial tests if a newer type of PET scan (FAPI PET) can better diagnose pleural mesothelioma than a standard FDG PET scan. If you have a suspicious spot in your lung lining and need a biopsy, this study may help improve how we find and track this cancer.
Aalborg, Region North JutlandAges 18 years+ - NCT06669312Recruiting
Study on a model for ICU patients on high-flow oxygen
This study is testing an existing model (BREF) to see how well it helps doctors make decisions for patients on high-flow oxygen in the intensive care unit. It may help improve care for people needing extra breathing support.
Rozzano, MilanAges 18 years+ - NCT06225258RecruitingPhase 2
Hops compound for septic shock treatment
This trial tests whether a natural compound from hops (xanthohumol) can help people with severe septic shock. It's given early, within the first day, alongside standard intensive care.
Lublin, Lublin VoivodeshipAges 18 years+ - NCT06850350Recruiting
Long COVID and Thinking & Walking
This study looks at how Long COVID affects thinking and movement skills. If you had COVID-19 more than 3 months ago and could walk before you got sick, you may be able to help researchers understand these lasting symptoms.
Chicago, IllinoisAges 18 years+ - NCT06846736Enrolling by invitation
Predicting ALK cancer treatment outcomes using digital pathology
This study uses a computer to analyze digital images of tumor tissue from people with a certain type of lung cancer (ALK-positive non-small cell lung cancer). It aims to see if the computer can predict how well newer-generation ALK inhibitors work in these patients.
Ramat GanAges 18 years+ - NCT06848699RecruitingPhase 1/Phase 2
Testing HLX43 plus Serplulimab for advanced solid tumors
This trial tests a new combination of two cancer drugs (HLX43 and Serplulimab) for people with advanced solid tumors, especially those with a specific type of lung cancer (NSCLC) that has an EGFR mutation. The goal is to see if this combination can shrink tumors or slow their growth.
Hunan, ChangshaAges 18–75 - NCT06846554RecruitingPhase 2
Study of APL-9796 for Pulmonary Hypertension with CardioMEMS Monitor
This trial tests a study drug called APL-9796 for people with pulmonary hypertension (PH). It may help by using your CardioMEMS monitor to see how well the drug works. You can take part only if you have a CardioMEMS implant and your PH is not too mild or too severe.
London, LondonAges 18–80 - NCT06855771RecruitingPhase 2
Study of navlimetostat alone or with izalontamab for advanced lung cancer
This trial tests a new drug, navlimetostat, either by itself or combined with another drug, izalontamab, for people with advanced non-small cell lung cancer that has a specific genetic change (MTAP loss). The goal is to see if these treatments can help shrink tumors or slow cancer growth.
Anchorage, AlaskaAges 18 years+ - NCT06851403Enrolling by invitation
Dupilumab for children with asthma in China
This study looks at how well and how safely the medicine Dupilumab works for children whose asthma is not well-controlled with their current inhalers. The goal is to see if it can help reduce asthma attacks and improve daily life.
Guangzhou, GuangdongAges 4–16 - NCT06850220Recruiting
How sleep apnea affects thinking and empathy in kids
This study looks at how obstructive sleep apnea caused by enlarged tonsils or adenoids might affect a child's thinking skills and ability to understand others. It will help doctors learn if treating the sleep problem could also help with these skills.
Suzhou, JiangsuAges 3–12 - NCT06851195Enrolling by invitation
Electrical stimulation for leg strength in COPD
This trial tests whether a gentle electrical stimulation applied to your leg muscles can help you feel less breathless and less tired during daily activities, and improve your confidence in exercising. It is for people with stable COPD who are already in a pulmonary rehab program.
Kaohsiung, TaiwanAges 18 years+ - NCT06854627Recruiting
Comparing two ways of lying face down for ARDS patients
This study compares lying face down continuously for a long time versus lying face down for shorter periods each day. It is for patients with moderate to severe ARDS (a serious lung condition) who are on a breathing machine. The goal is to see which approach helps the lungs recover better.
Buenos AiresAges 18 years+ - NCT06849596Recruiting
Breathing help for extremely premature babies at birth
This study compares two ways to help extremely premature babies breathe right after birth: using a manual T-piece or a ventilator. The goal is to find which method is safer and more effective.
Los Angeles, CaliforniaAges 6 months–7 months
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.