Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT07090395Recruiting
Expanding use of EVO oral appliance for severe sleep apnea
This trial tests whether an EVO oral appliance can treat severe obstructive sleep apnea in people who haven't used other treatments recently. It aims to see if the device works for a wider group of patients.
New York, New YorkAges 18–80 - NCT07091305RecruitingPhase 2
Study of a new drug with chemotherapy for limited-stage small cell lung cancer
This trial tests an investigational drug called QL1706 combined with chemotherapy, given after standard chemoradiation, for people with limited-stage small cell lung cancer. The goal is to see if this combination helps keep the cancer from coming back.
ShanghaiAges 18–75 - NCT07093580RecruitingPhase 1
Study of a long-acting injectable in healthy adults
This study tests a new long-acting injectable medication (S-892216 LAI) in healthy adults. It helps researchers understand how the drug works in the body when given as a shot, which could lead to a treatment given less often in the future.
Lenexa, KansasAges 18–55 - NCT07093749Recruiting
Antibiotics and symptom tracking in children
This study looks at how children with common infections feel while taking antibiotics. The goal is to better understand symptom patterns during treatment.
Melbourne, VictoriaAges 4–17 - NCT07094204RecruitingPhase 1
A study of ASP5834 for adults with solid tumors and KRAS mutations
This trial is testing a new drug called ASP5834 for people with advanced solid tumors that have a specific change in the KRAS gene. The study will find the best dose and see if it helps shrink tumors.
Santa Monica, CaliforniaAges 18 years+ - NCT07095361RecruitingPhase 4
Daily enzyme therapy for infected pleural fluid
This trial tests a once-daily enzyme treatment given through a chest tube to clear infected fluid from around the lungs. It may help people with complicated pneumonia or empyema who still have fluid buildup after initial drainage.
New Haven, ConnecticutAges 18 years+ - NCT07096258Recruiting
Blood test to guide first treatment for advanced lung cancer
This trial is for people with advanced non-small cell lung cancer (NSCLC) who have not yet started treatment. It studies a simple blood test that checks for genetic changes in the cancer, to help doctors choose the most effective first treatment.
Nancy, LorraineAges 18 years+ - NCT07096882RecruitingPhase 1
SDTM001 injection after lung cancer surgery
This trial tests an injection called SDTM001 as an extra treatment after surgery for people with non-small cell lung cancer (NSCLC). It aims to see if it can help prevent the cancer from coming back.
Chengdu, SichuanAges 18–70 - NCT07098338RecruitingPhase 2
New drug combos for advanced lung cancer
This trial tests new drug combinations for people with advanced or metastatic non-small cell lung cancer (NSCLC). Depending on your PD-L1 level and genetic profile, you may be placed in one of three groups to see if these combinations help shrink or control your tumor.
Santa Monica, CaliforniaAges 18 years+ - NCT07098403RecruitingPhase 3
Study of SHR-1905 for severe uncontrolled asthma
This trial tests an experimental drug called SHR-1905 for people with severe asthma that is not well controlled by their current treatments. The study aims to see if the drug can reduce asthma attacks and improve breathing.
Guangzhou, GuangdongAges 18 years+ - NCT07098611Recruiting
New tool to predict readiness for breathing tube removal
This study tests a new scoring tool to help doctors decide when a patient on a breathing machine is ready to have the tube removed safely. It is for patients who are currently in the process of being weaned off the ventilator.
Punta ArenasAges 18–89 - NCT07098910Recruiting
Surfactant therapy for premature babies with breathing problems
This trial tests whether giving surfactant (a substance that helps lungs stay open) to premature babies with Respiratory Distress Syndrome (RDS) through a mask on the throat (supraglottic airway) is safe and effective. It may be an option for babies who need extra oxygen but are not on a breathing tube.
HanoiAges Up to 2 days - NCT07099027Recruiting
Lung Health Check Pilot For Smokers Aged 55-74
This study is a lung health check pilot to find lung cancer early in people who are at higher risk because of their age and smoking history. You will get a free, low-dose CT scan to check for any signs of lung cancer.
DublinAges 55–74 - NCT07099144Recruiting
Inhaled nitric oxide for newborns with breathing failure and high blood pressure in the lungs
This trial tests whether inhaled nitric oxide gas can help full-term newborns who have severe breathing problems and high blood pressure in their lungs. It aims to improve oxygen levels and reduce the need for more intensive support.
Guangzhou, GuangdongAges Up to 1 week - NCT07099976Recruiting
Better pneumonia treatment for kids in the ER
This trial tests a treatment plan for children with pneumonia who can be treated at home. It aims to find the best way to help kids get better faster and avoid complications.
Calgary, AlbertaAges 6 months–18 years - NCT07100080RecruitingPhase 2/Phase 3
New drug vs chemotherapy for EGFR-mutated lung cancer
This trial tests a new drug called izalontamab brengitecan (BMS-986507) against standard chemotherapy (platinum plus pemetrexed) for people with a specific type of lung cancer that has an EGFR mutation and has stopped responding to newer targeted pills.
Irvine, CaliforniaAges 18 years+ - NCT07100860Recruiting
Lung surgery study: how breathing tube time affects recovery
This study checks if the length of time one lung is ventilated (breathing for you) during chest surgery affects your risk of lung complications after surgery. It may help doctors plan safer surgeries.
Ankara, AnkaraAges 18–85 - NCT07101796Recruiting
Mood and personality in sleep apnea treatment
This study looks at how mood and personality traits affect treatment adherence in people with suspected or confirmed sleep apnea. It may help tailor support for better treatment outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07102147Recruiting
Telehealth Therapy for Lung Cancer Patients at Penn Medicine
This trial offers therapy sessions (via phone or video) for people with lung cancer who are dealing with depression, anxiety, or other emotional concerns. It's part of Penn Medicine's collaborative care program and aims to make mental health support easier to access while you are being treated for lung cancer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07102589Recruiting
Walking test to measure exercise ability before lung surgery
This trial uses a shuttle walking test to see how well people with chronic lung disease can exercise before and after lung surgery. It may help doctors better understand recovery and plan care.
Seongnam-si, Not Required For This CountryAges 40 years+ - NCT07102823Recruiting
A registry study of lung blood vessel health in COPD
This study aims to better understand how COPD affects the blood vessels in your lungs by looking at measurements from a right heart catheterization. It may help doctors identify a specific pattern of lung and heart problems in people with COPD.
GrazAges 18 years+ - NCT07103395RecruitingPhase 2
Study of chemo, radiation, and dual immunotherapy for stage 3 lung cancer
This trial tests combining chemotherapy, radiation therapy, and two immune-boosting drugs (iparomlimab and tuvonralimab) as a first treatment for locally advanced non-small cell lung cancer that cannot be surgically removed. It aims to see if this combination improves outcomes compared to standard care.
Guangzhou, GuangdongAges 18–75 - NCT07103512Recruiting
Scalene hold-relax therapy plus standard physical therapy for asthma
This study tests whether adding a gentle muscle-relaxation technique for neck muscles to standard physical therapy can help people with allergic asthma breathe easier.
Mānsehra, Khyber PkahtoonKhwaAges 22–44 - NCT07103941Recruiting
Study of whether MAD therapy prevents bite changes
This study tests how well a dental device called a Mandibular Advancement Device (MAD) prevents changes in your bite and jaw alignment. It is for adults with sleep-disordered breathing who already have healthy, well-restored teeth.
Lexington, KentuckyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.