Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT06422143RecruitingPhase 3
Keytruda with or without Sac-TMT for advanced squamous lung cancer
This trial tests the combination of pembrolizumab (Keytruda) with or without a new drug, sacituzumab tirumotecan (Sac-TMT), as initial treatment for advanced squamous non-small cell lung cancer. It aims to see if adding Sac-TMT after initial treatment helps keep cancer under control longer.
Little Rock, ArkansasAges 18 years+ - NCT05776927RecruitingPhase 3
Testing a new inhaler for teens with asthma
This trial tests a new combination inhaler (QVM149) against a standard one (Advair) in teenagers with asthma that isn't well controlled by their current medicine. It aims to see if the new inhaler works better.
Rosario, Santa Fe ProvinceAges 12–17 - NCT07659782RecruitingPhase 2
Study of VS-7375 for KRAS G12D lung cancer
This trial tests a new drug, VS-7375, for people with advanced non-small cell lung cancer that has a specific genetic change called KRAS G12D. It's for those who have already tried chemo and immunotherapy, and whose cancer has continued to grow.
Scottsdale, ArizonaAges 18 years+ - NCT06869499Recruiting
Screening for a rare enzyme disease in patients with lung scarring
This study checks if people with certain lung changes (called interstitial lung disease) might have a rare enzyme deficiency that can cause lung and other organ problems. Finding this could lead to better treatment options.
ParisAges 15–60 - NCT06889467Recruiting
Testing leftover fluid from lymph node biopsies to find lung cancer
This trial is for people who are scheduled for a lung cancer biopsy (EBUS-TBNA) because doctors suspect non-small cell lung cancer (NSCLC) has spread to lymph nodes. It will test leftover fluid from the biopsy to see if it improves cancer detection. If your biopsy is negative but you still need surgery to remove lymph nodes, you can help us learn more about this new test.
AshkelonAges 18 years+ - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Huntsville, AlabamaAges 12 years+ - NCT07153055RecruitingPhase 1/Phase 2
Lurbinectedin with osimertinib for transformed small cell lung cancer
This trial tests a combination of two drugs—lurbinectedin and osimertinib—for people whose lung cancer started as EGFR-mutated non-small cell lung cancer but has changed into small cell lung cancer. The goal is to see if this combination can help control the cancer.
Indianapolis, IndianaAges 18 years+ - NCT07149363RecruitingPhase 2
Chemo and immunotherapy after surgery for small cell lung cancer
This trial tests whether adding immunotherapy (durvalumab) to standard chemotherapy after surgery can help prevent small cell lung cancer from coming back. It is for people who have had their cancer completely removed and are well enough to start treatment soon after surgery.
Chicago, IllinoisAges 18 years+ - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07652736Recruiting
Tislelizumab for lung cancer in routine care
This study watches how well Tislelizumab works for people with lung cancer when it is used as part of their normal treatment. It does not give you any new medicine or change your care plan.
CórdobaAges 18 years+ - NCT07289646RecruitingPhase 3
Lung perfusion scan to guide radiation planning for lung cancer
This study compares two ways of planning radiation treatment for lung tumors. One method uses a special scan to see which parts of your lungs work best, aiming to protect healthy lung tissue, while the other uses a standard anatomical approach. The goal is to see if the functional approach can reduce side effects and improve outcomes.
Brest, FinistèreAges 18 years+ - NCT07194382RecruitingPhase 2
Testing a new liquid form of nintedanib for IPF
This trial tests a liquid version of the medication nintedanib (AP02) to see if it is safe and works well for people with idiopathic pulmonary fibrosis (IPF). If you have IPF and have not taken nintedanib or pirfenidone recently, you may be able to join.
Camperdown, New South WalesAges 40 years+ - NCT06712316RecruitingPhase 2/Phase 3
New drug plus chemotherapy for advanced lung cancer
This trial tests a new investigational drug combined with chemotherapy for people with advanced non-small cell lung cancer that has not been treated before. The goal is to see if it is safe and works better than current treatments.
Birmingham, AlabamaAges 18 years+ - NCT06520592Enrolling by invitation
Augmented reality to help CPAP use for sleep apnea
This study tests whether using augmented reality (AR) can make it easier for people with moderate to severe sleep apnea to use a CPAP machine, which helps keep their airway open during sleep. It aims to see if AR can improve comfort and adherence to CPAP therapy.
Tainan, TaiwanAges Any age - NCT07215871Enrolling by invitationPhase 1
Second H10N7 flu challenge for prior participants
This study tests whether people who have already been exposed to a lab-made H10N7 flu virus can be safely exposed again. It checks how their immune system responds and how long they shed the virus, in a controlled, isolated setting.
Bethesda, MarylandAges 18–55 - NCT07354074RecruitingPhase 2
Study of asciminib for children with Ph+ CML
This trial tests an oral medication called asciminib in children and teens with a type of leukemia called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). It aims to see if the drug is safe and effective for patients who are newly diagnosed or whose current treatment has stopped working or caused side effects.
New Brunswick, New JerseyAges 1–18 - NCT02527486Recruiting
Airways registry study for people with COPD symptoms
This registry collects information from people with COPD (and sometimes overlapping asthma-COPD features) to better understand breathing problems and airways behavior. It may help researchers learn which patterns match different symptom types, without necessarily using a new drug.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT02917369Recruiting
Study of integrative care for large-cell lung cancer
This trial is looking at an approach to treat large-cell lung cancer. It may help people who have not yet had cancer chemotherapy and who are well enough to do day-to-day activities.
Ganzhou, JiangxiAges 18–75 - NCT03120481Recruiting
Check how respiratory health changes in people without lung problems
This trial enrolls adults who recently had a chest X-ray as part of routine health screening and did not show major abnormal findings, and who do not have significant breathing symptoms. It may help researchers understand changes in respiratory health over time and improve how respiratory disease risk is monitored.
Seoul, SeoulAges 19–90 - NCT02947945RecruitingPhase 2
Reslizumab for EGPA in adults
This trial tests reslizumab, a medicine that targets a specific immune signal, to improve symptoms in people with eosinophilic granulomatosis with polyangiitis (EGPA). It may help lower disease activity and reduce inflammation-related problems.
Denver, ColoradoAges 18 years+ - NCT03392233RecruitingPhase 2
Targeted radiation for spinal metastases causing significant pain
This trial tests a focused form of radiation (stereotactic body radiation) to treat cancer spread to the spine, especially when it causes substantial pain. It may help shrink or control the spinal spots while limiting damage to surrounding tissues.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT03528525Recruiting
Study of breathing-related rare genetic diseases in Chinese children
This registry study collects and stores samples from children with breathing-related rare genetic (inherited) diseases to learn more over time. It may help researchers better understand these conditions and improve future care, especially through long-term follow-up.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT03659019Recruiting
Database study for implanted phrenic nerve stimulators
This study collects information about people with long-term breathing problems who may receive an implanted device that helps control breathing. It helps doctors better understand who benefits and how these treatments are used in real life.
Paris, Île-de-France RegionAges 5 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.