Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05668650RecruitingPhase 3
Study MB12 versus Keytruda for newly diagnosed stage IV lung cancer
This Phase 3 trial compares MB12 with Keytruda (both cancer medicines) for people with newly diagnosed stage IV non-squamous non-small-cell lung cancer. It looks at whether MB12 can work as well or better than Keytruda, and compares safety and immune responses.
Viedma, Río Negro ProvinceAges 18 years+ - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+ - NCT07362433RecruitingPhase 4
AI stethoscope to guide antibiotic use in children with mild pneumonia
This trial tests whether an AI-powered stethoscope can help doctors decide when to use antibiotics for children with mild pneumonia. It aims to avoid unnecessary antibiotics while still treating those who need them.
SylhetAges 2 months–4.9 years - NCT07362342Recruiting
Right heart function after lung lobe removal surgery
This study looks at how the right side of the heart handles the stress of having a lung lobe removed. It compares different surgery types (VATS, robotic, or open) and focuses on people with moderate to high heart and lung risk factors.
Rozzano, MIAges 18 years+ - NCT07363252Recruiting
Study of why lung cancer returns after osimertinib treatment
This study looks at why lung cancer returns in people who took the targeted pill osimertinib after surgery. If your cancer has come back, researchers will test your tumor or blood sample to understand how the cancer changed.
Bari, BAAges 18 years+ - NCT05734365Recruiting
COPD patients admitted to ICU after a flare, for registry
This observational study collects information on people with COPD (chronic lung disease) who have a severe flare requiring ICU care. It does not test a new drug, but the data may help doctors better understand severe COPD episodes and ICU outcomes.
Le ChesnayAges 40 years+ - NCT06557941Recruiting
Risk factors for breathing tube removal failure in children
This study looks at why some children in the pediatric ICU have trouble coming off the breathing machine (ventilator). If your child is ready to try stopping the ventilator, this trial will help doctors understand what may make that transition safer.
SohagAges 4 weeks–18 years - NCT07362069Enrolling by invitation
Virtual reality program to prevent teen vaping
This trial tests whether a virtual reality experience can help 8th graders avoid or stop using e-cigarettes. School staff will also learn how to support students' mental health.
New Haven, ConnecticutAges 12–15 - NCT05773001RecruitingPhase 1
Study of an immune treatment for ozone-related lung inflammation
This early-phase study tests how an immune-targeting treatment affects inflammation in the lungs after ozone exposure. It may help researchers understand—and eventually reduce—lung inflammation triggered by air pollution.
Durham, North CarolinaAges 18–55 - NCT06807307Recruiting
Using genetic tests to predict immunotherapy response in lung cancer
This study looks at genetic material from tumor samples to find patterns that can predict whether immunotherapy will work for people with advanced non-small cell lung cancer (NSCLC). The goal is to improve how doctors choose treatments for each patient.
RomeAges 18 years+ - NCT07358039Recruiting
Recruitment maneuver after suctioning in ICU patients on ventilators
This study is testing whether a breathing maneuver after suctioning helps restore lung volume in intensive care patients who are on a ventilator. It may help improve breathing and recovery.
Toulon, VARAges 18 years+ - NCT07357051RecruitingPhase 3
Flu treatment study for children ages 2 to 12
This trial tests a new oral medicine (JKN2301) for children with the flu. It aims to see if the medicine is safe and works well to treat flu symptoms like fever and cough.
Guangzhou, GuangdongAges 2–11 - NCT06362252RecruitingPhase 1/Phase 2
I-DXd plus atezolizumab for first-line extensive SCLC
This trial tests a new combination of drugs (I-DXd and atezolizumab, with or without carboplatin) as your first treatment for extensive stage small cell lung cancer. It has two groups: one for people who haven't started treatment yet, and another for those who've already had 4 cycles of a standard chemo-immunotherapy combination and are stable or better.
Birmingham, AlabamaAges 18 years+ - NCT07347366Recruiting
Chest vibration device for mucus clearance in pneumonia
This study tests a device that uses gentle vibrations on your chest to help move mucus out of your lungs. It is for hospitalized adults who have trouble coughing up phlegm due to pneumonia or similar infections.
Yangsan, Gyeongsangnam-doAges 18 years+ - NCT05967299RecruitingPhase 1
IV ZMA001 study in healthy adults
This Phase 1 trial tests how an IV medicine called ZMA001 behaves in healthy people and checks for early safety. It may help future studies of the drug by confirming dosing and effects in people before testing in patients.
Bethesda, MarylandAges 18–60 - NCT07340892Recruiting
Finding markers to predict lung inflammation from immunotherapy
This study looks for signs in the blood that can tell if a lung cancer patient is developing a side effect called pneumonitis (lung inflammation) from checkpoint inhibitor treatment. It may help doctors catch and treat this side effect early.
Guangzhou, GuangdongAges 18 years+ - NCT06486168Recruiting
Diaphragm weakness after non-intubated lung surgery
This study looks at how often the diaphragm (the main breathing muscle) weakens after lung surgery done without a breathing tube. It aims to help doctors understand recovery and prevent future breathing problems.
Quincy-sous-SénartAges 18 years+ - NCT06090253Recruiting
Sport exercise program for healthy aging over 60
This trial tests a program that uses sports and exercise to help people over 60 stay healthy and active. It looks at both how well the program works and how easy it is to put into practice.
Hong KongAges 60 years+ - NCT06945120Recruiting
Lung Health Program for Chinese and Korean Smokers
This study is testing a program to help Chinese and Korean adults who smoke to improve their lung health. You may be able to join if you are a current smoker, speak Korean, Mandarin, or English, and live in the U.S.
Boston, MassachusettsAges 18–100 - NCT06487052Recruiting
Catheter-based clot-dissolving drug for intermediate-high risk pulmonary embolism
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
Saint PetersburgAges 18 years+ - NCT07326540RecruitingPhase 3
Testing a new antibiotic for drug-resistant pneumonia in the hospital
This trial compares a new antibiotic (BV100 plus low-dose polymyxin B) against a standard treatment for pneumonia caused by a hard-to-treat bacteria (Acinetobacter baumannii). If you have hospital-acquired or ventilator-associated pneumonia and standard antibiotics aren't working, this study may offer a new option.
TbilisiAges 18–82 - NCT06488300RecruitingPhase 2
Testing antiviral treatments for early RSV
This trial tests if antiviral medications can help adults with early respiratory syncytial virus (RSV) feel better faster. It is for people aged 18 to 64 who have had RSV symptoms for 4 days or less and have tested positive for the virus.
VientianeAges 18–64 - NCT05701176Recruiting
Imaging scan to see how anti–PD-1 changes lung cancer cells
This study uses special PET imaging to measure changes in a marker ([18F]F-AraG) in non-small cell lung cancer after starting anti–PD-1 treatment. It aims to learn whether these scan changes reflect how the cancer responds.
AmsterdamAges 18 years+ - NCT07325773Recruiting
Can magnesium help lung function during one-lung breathing?
This trial tests if giving magnesium during surgery helps oxygen levels in the blood and supports lung mechanics when only one lung is used for breathing.
IstanbulAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.