Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07503509Recruiting
Study of high PEEP in noninvasive ventilation
This study tests whether using higher pressure settings (PEEP) on a noninvasive breathing mask can help people with low oxygen levels. The doctors will measure the pressure inside your esophagus to guide the treatment.
Chongqing, Chongqing MunicipalityAges 18–100 - NCT07504367Recruiting
AI assistance in tumor treatment meetings
This study tests whether a large language model can help doctors make better decisions in tumor multidisciplinary team meetings. It evaluates junior doctors with specific experience levels.
Guangzhou, GuangdongAges 25–33 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT00682032Recruiting
Beta-glucan for non-small cell lung cancer
This study tests whether beta-glucan, a supplement taken by mouth, can help people with non-small cell lung cancer. You may be able to join if you’re newly diagnosed (no recent treatment) and can safely take pills.
Louisville, KentuckyAges 18 years+ - NCT06422403RecruitingPhase 2
Study on giving immunotherapy less often for advanced cancer
This trial tests whether giving certain immunotherapy drugs less often than usual is safe and still works well for people with advanced stomach, liver, or lung cancer. It might mean fewer hospital visits while still controlling the cancer.
SingaporeAges 21–99 - NCT06769971RecruitingPhase 2
Ivonescimab and cadonilimab plus chemo for extensive-stage small cell lung cancer
This trial tests a combination of two experimental immunotherapy drugs (ivonescimab and cadonilimab) with standard chemotherapy for people with extensive-stage small cell lung cancer who have not had prior treatment. The goal is to see if this combination works better than chemo alone.
Chengdu, SichuanAges 18–75 - NCT06769295RecruitingPhase 2
Study of AK112 plus chemo for advanced lung cancer
This trial tests a new drug, AK112, combined with chemotherapy for people with advanced non-squamous non-small cell lung cancer that has spread to the lining of the lung (malignant pleural effusion). The goal is to see if this combination helps shrink tumors and improve outcomes.
Chengdu, SichuanAges 18–75 - NCT06741137Recruiting
Inhaled nitric oxide and prone positioning for ARDS
This trial is testing whether adding inhaled nitric oxide to lying on your stomach (prone position) can help people with severe lung failure (ARDS) who are on a ventilator. It uses a special monitor (EIT) to check lung function in real time.
Yangzhou, JiangsuAges 18–80 - NCT06768008Recruiting
Integrated care model for newborns with critical heart disease
This trial tests a coordinated treatment plan for newborns with critical congenital heart disease, starting before birth and continuing after delivery. It aims to improve outcomes for babies who need two-ventricle repair surgery.
BeijingAges 1 day–4 weeks - NCT07495982Recruiting
Inflammation markers and CT scans in stable bronchiectasis
This study looks at whether certain blood tests and CT scans can help predict when someone with bronchiectasis might have a flare-up (worsening of symptoms). It may help doctors better understand and manage the condition.
SohagAges 18 years+ - NCT07494006Enrolling by invitation
Which breathing mode is safer during lung surgery?
This trial compares two ways of helping you breathe during lung surgery to see which one keeps your oxygen levels more stable. You will be randomly assigned to breathe either normally or with a special mode during the one-lung part of the surgery.
BeijingAges 18 years+ - NCT07493356Recruiting
Predicting difficult airway with STOP-BANG criteria
This trial tests whether the STOP-BANG checklist can help doctors predict when a patient might have a difficult airway during surgery. If you are overweight and having planned surgery with a breathing tube, you may be eligible.
Karachi, SindhAges 18–60 - NCT07492342RecruitingPhase 2
Fulzerasib with immunotherapy and chemo before surgery for KRAS G12C lung cancer
This trial tests a combination of a targeted pill (Fulzerasib) and immunotherapy (Sintilimab) plus standard chemotherapy before surgery, for people with early-stage non-small cell lung cancer that has a specific KRAS G12C mutation. The goal is to shrink the tumor and make surgery more effective.
BeijingAges 18 years+ - NCT07495774Recruiting
Pediatric pulmonary hypertension registry study
This study collects information from children with pulmonary hypertension (high blood pressure in the lungs) to better understand the condition and improve care. If your child has been diagnosed with PH, joining this registry will help doctors track their health over time.
Guangzhou, GuangdongAges Up to 18 years - NCT07490860Recruiting
Supporting Black adults to decide about lung cancer screening
This study tests a program called RESTORE that helps Black adults who smoke make informed decisions about lung cancer screening. The program uses restorative justice principles to support you in talking with your doctor.
Seattle, WashingtonAges 50–77 - NCT07498244Recruiting
Collagen fingerprinting to understand lung blood pressure
This study uses a special imaging method to look at collagen (a building block of lung tissue) in people with COPD or pulmonary fibrosis. Researchers want to see if collagen patterns can help doctors better understand and treat high blood pressure in the lungs (pulmonary hypertension).
Graz, StyriaAges 18 years+ - NCT07491094Recruiting
Repeated exams for pulmonary embolism follow-up
This study looks at repeated scans and tests for people who have had a pulmonary embolism (PE) — a blood clot in the lungs. It aims to improve how doctors monitor recovery and decide on treatment.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT07493837Recruiting
Comparing land and water breathing muscle training in young swimmers
This trial compares two ways of training the muscles you use to breathe—either on land or in water—to see which helps young swimmers improve their swimming performance. It may help you breathe more easily and swim faster.
Samsun, AtakumAges 13–18 - NCT07493187Recruiting
MRI for non-cancer lung diseases
This study uses MRI scans to look at the lungs of people with early-stage IPF, a lung scarring disease. It aims to see how well MRI can show lung changes without using radiation.
Pavia, LombardyAges Any age - NCT07495436Recruiting
Video vs. direct laryngoscopy for children's breathing tubes
This study compares two ways of placing a breathing tube in children during surgery: using a video camera laryngoscope or a standard direct laryngoscope. If your child is having a planned surgery and needs a breathing tube, this trial may help determine which method is safer and easier.
Santiago de Compostela, A CORUÑAAges birth–16 hours - NCT07498127Enrolling by invitationPhase 2
Probiotics for colds in young children
This trial tests whether taking probiotics can help young children recover faster from common colds. If your child has a mild or moderate cold and is not taking other probiotics, they may be able to join.
Xuhui, Shanghai MunicipalityAges 3 months–6 years - NCT07491497RecruitingPhase 1/Phase 2
TRI-611 for ALK-positive lung cancer
This study tests an experimental pill for people with a specific type of lung cancer. The trial will see if the drug is safe and if it helps shrink tumors.
San Francisco, CaliforniaAges 18 years+ - NCT07489911Recruiting
Real-world study of triple inhaler for uncontrolled asthma
This study tests a triple-inhaler called Trimbow for people whose asthma is not well controlled despite using other inhalers. The goal is to see if switching to Trimbow helps reduce asthma attacks and improve day-to-day breathing.
CeljeAges 18 years+ - NCT07492771RecruitingPhase 1
Study of MP101 for adults with Pseudomonas pneumonia
This trial tests an experimental treatment called MP101 for adults with pneumonia caused by the bacteria Pseudomonas aeruginosa (PA). It aims to help patients whose infection is not responding to current antibiotics.
Seoul, Seodaemun-guAges 19 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.