Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07778316RecruitingPhase 3
Tarlatamab for small cell lung cancer after first chemotherapy
This trial tests a new drug called tarlatamab, given either as an injection under the skin or through an IV, for people with extensive-stage small cell lung cancer that has grown or come back after one round of chemotherapy. The goal is to see which way of giving the drug works better and is safer.
Grand Rapids, MichiganAges 18–99 - NCT07778121Recruiting
Sleep apnea screening for people with type 2 diabetes
This study tests a home-based screening method for obstructive sleep apnea (a condition where breathing stops briefly during sleep) in people with type 2 diabetes. It aims to find undiagnosed cases, which could improve health and quality of life.
KøgeAges 18 years+ - NCT06077760RecruitingPhase 3
Personalized cancer vaccine plus Keytruda for lung cancer after surgery
This study tests a new personalized cancer vaccine (V940) plus Keytruda versus a placebo plus Keytruda for people with non-small cell lung cancer that was removed by surgery. The goal is to see if the vaccine helps prevent the cancer from coming back.
Anchorage, AlaskaAges 18 years+ - NCT05963867RecruitingPhase 1
First-dose study of a cancer drug taken up by tumors
This Phase 1 study tests how BI 764532 moves into and through tumors in people with small-cell lung cancer or neuroendocrine cancer. It’s likely aimed at understanding the drug’s behavior in your body and tumor, especially if you’ve already tried standard treatments.
AmsterdamAges 18 years+ - NCT06594627Recruiting
Smart pillow study for better sleep with snoring or sleep apnea
This study tests a smart pillow device to see if it can improve sleep quality for people over 50 who snore or have mild sleep apnea. It also looks at how the pillow affects sleep partners.
Indianapolis, IndianaAges 50 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT07623369RecruitingPhase 1
First-in-Human Study of HH160 for Advanced Solid Tumors
This is an early-stage trial testing a new drug called HH160 in patients with advanced cancer (solid tumors). Researchers want to find the right dose and learn how well it works and what side effects it causes.
Waratah, New South WalesAges 18–75 - NCT07195695RecruitingPhase 3
Zongertinib after surgery for HER2-mutated lung cancer
This trial tests a new pill, zongertinib, against standard of care for people with early-stage (II–IIIB) non-small cell lung cancer that has a specific HER2 mutation in the tyrosine kinase domain. The goal is to see if zongertinib can prevent the cancer from coming back after complete surgical removal.
Fresno, CaliforniaAges 18 years+ - NCT06498635RecruitingPhase 3
Immunotherapy after surgery for lung cancer with no remaining cancer
This trial tests whether giving immunotherapy (durvalumab) after surgery can help prevent lung cancer from coming back if you already had a complete response to chemo and immunotherapy before surgery. It is for people with early-stage non-small cell lung cancer who had no cancer left after treatment.
Jonesboro, ArkansasAges 18 years+ - NCT07674264Recruiting
Breathing therapy for thinking and movement in Parkinson's
This study tests whether a breathing-based therapy (short bursts of controlled air with higher carbon dioxide) can help with thinking and movement in people with Parkinson's disease. It may be an option for those who are not too advanced in their condition and are healthy enough to participate.
Gainesville, FloridaAges 40–75 - NCT06824961Recruiting
Comparing 3 vs 5 second pauses during CPR for cardiac arrest
This trial is testing whether increasing the pause in chest compressions from 3 to 5 seconds during CPR helps improve breathing support and the chance of restarting the heart. It involves adults who had a cardiac arrest outside the hospital and were treated with a mechanical compression device called LUCAS.
Amsterdam, North HollandAges 16 years+ - NCT06739031Recruiting
Testing pulsed electric field ablation for small lung tumors
This trial tests a new treatment that uses short electrical pulses (pulsed electric field ablation) to destroy small lung tumors. It may be an option for people with limited, early-stage non-small cell lung cancer who can tolerate a minimally invasive procedure.
ShanghaiAges 18 years+ - NCT07168629Recruiting
Community health workers help you get lung cancer screening
This trial tests whether a community health worker can help you get a lung cancer screening. If you are at risk for lung cancer and go to certain community health centers, this program may help you get the screening you need.
Springfield, MassachusettsAges 50–80 - NCT07227207RecruitingPhase 1/Phase 2
Study of TSRA-196 for adults with Alpha-1 Antitrypsin Deficiency
This trial tests a new medicine called TSRA-196 for people with Alpha-1 Antitrypsin Deficiency who have the PiZZ genetic type. The study looks at whether TSRA-196 can help with lung or liver problems related to this condition.
Boston, MassachusettsAges 18–70 - NCT06871462Enrolling by invitation
Texting program to help monitor blood pressure at home
This study tests a program that uses text messages to help people with high blood pressure check and manage their blood pressure at home. It may help you better control your blood pressure and reduce health risks.
San Francisco, CaliforniaAges 18 years+ - NCT07283497RecruitingPhase 4
Itraconazole for bronchiectasis with airway mold growth
This Mayo Clinic study tests whether the oral antifungal drug itraconazole can help people with bronchiectasis who have mold growing in their airways. The goal is to see if it improves symptoms and reduces mold in the lungs.
Rochester, MinnesotaAges 18 years+ - NCT07531095RecruitingPhase 1
Combination drug trial for small cell lung cancer
This study tests three experimental drugs (tarlatamab, ZL-1310, and sometimes an immune-boosting drug) together to treat small cell lung cancer. The goal is to see if this combination can slow or shrink the cancer and help you live longer.
Goodyear, ArizonaAges 18–99 - NCT07532941RecruitingPhase 4
Stopping antibiotics early versus completing the full course
This study compares two ways of giving antibiotics to children: stopping when symptoms feel better versus finishing all the prescribed doses. Researchers want to see if stopping early is safe and works just as well, which could help reduce unnecessary antibiotic use.
Melbourne, VictoriaAges 1–17 - NCT07221474RecruitingPhase 2
Study of a personalized vaccine plus chemo for lung cancer
This trial tests an experimental personalized cancer vaccine (V940) combined with pembrolizumab and chemotherapy for people with advanced squamous non-small cell lung cancer that has spread. The goal is to see if adding the vaccine helps the immune system fight the cancer better.
Tampa, FloridaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT07227597RecruitingPhase 1/Phase 2
Study of two experimental drugs for advanced small cell lung cancer
This study tests two experimental drugs, gocatamig and ifinatamab deruxtecan, for people with advanced small cell lung cancer. The goal is to see if this combination can help control the cancer, either as a first treatment or after initial standard therapy.
Santa Rosa, CaliforniaAges 18 years+ - NCT05272241Recruiting
Asthma registry that helps researchers learn about asthma
This study enrolls people in specific cities to collect health information that helps researchers better understand asthma and how to recruit future studies. It may help by improving knowledge about asthma types and care in real-world settings.
Aurora, ColoradoAges Any age - NCT05920356RecruitingPhase 3
Tested KRAS-targeted sotorasib plus chemo vs pembrolizumab plus chemo
This Phase 3 trial tests whether sotorasib plus standard chemotherapy works better than pembrolizumab (an immunotherapy) plus standard chemotherapy as first treatment for certain advanced lung cancers. It may help people whose tumors have a KRAS G12C mutation and that do not show PD-L1 on testing.
Santa Barbara, CaliforniaAges 18–100 - NCT05691218Recruiting
Early high-flow oxygen plus nebulized asthma medicine
This study tests whether giving fast, high-flow oxygen early—together with inhaled terbutaline via a vibrating mist—helps adults with moderate to severe asthma flare-ups in the emergency department. It aims to see if this approach improves breathing after initial treatment.
Poitiers, FranceAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.