Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05925322Recruiting
Social reward therapy for depression-related suicidal thoughts
This study looks at whether “social reward” psychotherapy can change brain activity and reduce suicidal thoughts in adults ages 50–80 who also have major depression. You may be offered psychotherapy along with brain scans to see how your brain responds over time.
New York, New YorkAges 50–80 - NCT05933850Recruiting
Family program to improve parenting skills for caregivers
This trial tests a culturally adapted family support program aimed at improving parenting and family relationships for primary caregivers of children ages 8–15. If you qualify, you may receive structured sessions designed for families in Gilgit Baltistan, and outcomes will be tracked over the study period.
KarachiAges 18 years+ - NCT05935241Recruiting
Program mPATH for sleep and activity in older adults
This trial tests a program (mPATH) to help older adults with sleep trouble by improving activity and exercise habits. It may be helpful if you have low income and want support building moderate exercise safely.
Baltimore, MarylandAges 65 years+ - NCT05937594Recruiting
Testing microRNA markers to spot newborn opioid withdrawal
This study looks at tiny genetic signals (microRNA) in newborn samples to identify neonatal opioid withdrawal syndrome. It may help doctors recognize withdrawal sooner, so babies can get the right care faster.
Hershey, PennsylvaniaAges 1 day–5 days - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05917977Recruiting
Motivational interviewing for teens with gaming problems
This study tests a talking program (called motivational interviewing) that helps teens aged 10-16 who struggle with too much gaming. The goal is to help them build motivation to change their gaming habits.
ShatinAges 10–16 - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05928247Recruiting
Behavior program for frequent challenging behaviors in children
This trial tests a structured (manualized) assessment and treatment approach for children who have very frequent challenging behaviors despite prior help. It aims to reduce these behaviors and improve daily functioning by targeting what keeps the behavior going.
Somerset, New JerseyAges 3–17 - NCT05918835Recruiting
Transcranial magnetic stimulation for food choices in anorexia
This study tests if repeated transcranial magnetic stimulation (rTMS) can change how women with anorexia nervosa make food choices. You would receive rTMS while staying in a hospital eating disorders unit.
New York, New YorkAges 18–35 - NCT05927974Recruiting
Brain mapping during surgery for hard-to-control epilepsy
This trial studies how the brain’s control networks work during a surgery-related procedure for people with epilepsy that hasn’t improved with usual treatments. If you qualify, you may do specific tasks while the team maps and measures brain activity to better understand and guide care.
Birmingham, AlabamaAges 18 years+ - NCT05934175Recruiting
Intensive therapy vs weekly trauma therapy for PTSD
This trial compares an intensive course of prolonged exposure therapy versus a standard weekly schedule for adults with post-traumatic stress disorder (PTSD). It may help you and your care team choose a treatment schedule that reduces PTSD symptoms.
StockholmAges 18 years+ - NCT05931406Recruiting
Exercise breaks for emergency dispatchers
This study tests whether using a sit-stand desk and a cycle ergometer (a type of exercise bike) during work can improve health and reduce the effects of sitting too long. It is designed for people who work as emergency dispatchers or in similar roles.
Clermont-FerrandAges 18 years+ - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05929677RecruitingEarly Phase 1
Study tests effects on impulsivity and how alcohol feels
This early-phase study looks at how alcohol affects impulsivity (tendency to act quickly) and people’s subjective experiences. You may be able to join if you drink regularly and meet the study safety rules.
Boston, MassachusettsAges 21–25 - NCT03821857RecruitingPhase 4
Study of hormone disruption effects on aging and Alzheimer’s
This trial studies how hormone (endocrine) disruption may affect aging and Alzheimer’s disease in women. It may help researchers understand why these effects can differ by sex and how to better assess or track risk over time.
Jacksonville, FloridaAges 60 years+ - NCT01248767Recruiting
Study of treatment-seeking teens and adults with behavioral addiction
This study follows people who come to the hospital seeking help for a behavioral addiction and tries to better understand their needs and treatment path. It mainly involves completing assessments (questionnaires/interviews) to see how they’re doing.
NantesAges 15 years+ - NCT04855825Recruiting
Wearable robotic exoskeleton to improve walking and thinking in MS
This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.
West Orange, New JerseyAges 18–75 - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT05632497Recruiting
Testing gut microbiome changes in adults with anorexia
This study looks at how changing the gut bacteria (microbiome) may affect people hospitalized for anorexia nervosa. You may be eligible if you’re an adult with a very low BMI and meet the study’s timing and health requirements.
VillejuifAges 18 years+ - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05813457Recruiting
Early identification program for first episode psychosis
This study checks whether finding and starting care early for a first episode of psychosis can shorten how long symptoms go untreated. You may be eligible if it’s your first episode and you haven’t been on antipsychotic medicines for long before now.
BronAges 15–35 - NCT05884476Recruiting
Re-checking suicidal thoughts in Veterans during a study
This study looks at a way to re-evaluate and respond to suicidal thoughts in Veterans. It may help improve how support is offered when someone has had thoughts of suicide recently.
New Orleans, LouisianaAges 18 years+ - NCT05897021Recruiting
Writing exercises to ease stress for sexual minority veterans
This study tests whether guided “expressive writing” helps reduce distress linked to sexuality-based stress. It targets veterans who have meaningful anxiety or depression symptoms and ongoing stress related to their sexual identity.
Boston, MassachusettsAges 18 years+ - NCT05884853Recruiting
Social brain training for adults with autism
This study tests a brain training program for adults with autism to see if it improves social skills. It may help participants understand social situations better.
Taipei, Zhongzheng Dist.Ages 18–50
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.