Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05800535Recruiting
Screening for muscle loss and thinking changes after cancer
This study looks at how common muscle weakness (sarcopenia) and thinking or memory changes (often called “chemobrain”) are in people after cancer treatment. It may help teams understand what support could be most helpful after chemotherapy.
Pierre-BéniteAges 18–74 - NCT05835973Recruiting
Study of sleep changes in people with inflammatory bowel disease
This study looks at how sleep patterns change in adults with inflammatory bowel disease (IBD) who are currently in remission. It may help researchers understand sleep issues in IBD and identify ways to improve care during symptom-free periods.
Clermont-FerrandAges 18–65 - NCT05931289RecruitingPhase 2
Therapy plus brain scans after a recent suicide crisis
This Phase 2 study tests suicide-safety treatments given after a recent suicidal crisis or suicide attempt. It may help by reducing risk and understanding brain changes with follow-up brain scan visits.
Boston, MassachusettsAges 18 years+ - NCT05920252Recruiting
Phone-based suicide risk support for teens in DBT
This trial tests whether a smartphone tool can help reduce suicide risk for teens who are already in an intensive therapy program (DBT). It may help you or your family recognize risk earlier and use skills more consistently between sessions.
New York, New YorkAges 13–18 - NCT05926011Recruiting
Test RGn600 in mild to moderate Alzheimer’s patients
This trial studies whether RGn600 can help people with mild to moderate Alzheimer’s disease. You may be able to join if you meet age, test-score, scan, bloodwork, and safety requirements and can attend study visits with a regular caregiver.
CastresAges 55–85 - NCT05913752RecruitingPhase 1/Phase 2
Test drug CMND-100 in people with alcohol use disorder
This early study tests the safety and dosing of CMND-100 in first-time participants, including people with alcohol use disorder (AUD) and some healthy volunteers. It may help researchers understand whether the drug is safe, and how it might affect alcohol use in AUD.
New Haven, ConnecticutAges 18–60 - NCT05931406Recruiting
Exercise breaks for emergency dispatchers
This study tests whether using a sit-stand desk and a cycle ergometer (a type of exercise bike) during work can improve health and reduce the effects of sitting too long. It is designed for people who work as emergency dispatchers or in similar roles.
Clermont-FerrandAges 18 years+ - NCT05935553RecruitingPhase 2/Phase 3
Baclofen to help taper benzodiazepines more safely
This trial tests whether baclofen can make it easier to reduce (taper) benzodiazepines in people who have been dependent for a long time and previously had trouble stopping. If you can safely take part, it may help improve the tapering process and reduce withdrawal problems.
BronAges 18–65 - NCT05918835Recruiting
Transcranial magnetic stimulation for food choices in anorexia
This study tests if repeated transcranial magnetic stimulation (rTMS) can change how women with anorexia nervosa make food choices. You would receive rTMS while staying in a hospital eating disorders unit.
New York, New YorkAges 18–35 - NCT05915000Recruiting
CSF protein tests to predict shunt response in hydrocephalus
This study looks at fluid-based “CSF” protein markers to predict how well a brain shunt works in adults with chronic hydrocephalus (fluid buildup). If you qualify, your CSF sample may help doctors better estimate your likely response to treatment.
Valencia, ValenciaAges 18 years+ - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05924425RecruitingPhase 4
Daridorexant for insomnia in early memory decline
This trial tests whether daridorexant can improve sleep in people who have mild cognitive impairment or early Alzheimer’s disease and struggle with insomnia. It may help by improving how long and how well you sleep, with monitoring of sleep patterns and memory-related measures.
MontpellierAges 60–85 - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05923801Recruiting
Optimizing ECT treatment for difficult depression
This trial studies better ways to deliver ECT (electroconvulsive therapy) for people with difficult-to-treat depression, including some people with bipolar depression. You may be offered an ECT strategy that’s tailored to your situation, with the goal of improving outcomes and reducing problems.
KortenbergAges 18 years+ - NCT05925101Recruiting
Studying ways to reduce frequent behavior spikes in children
This study looks at basic and applied methods to understand “extinction bursts,” times when a hard-to-control behavior may briefly get worse before it improves. It may help families and clinicians choose safer, more effective behavior supports for children with very frequent problem behaviors.
Somerset, New JerseyAges 3–17 - NCT05927350Recruiting
Transgender and gender-diverse teens research participation
This study is looking for teens ages 15 to 21 who identify as transgender or gender-diverse (their gender identity is different from the sex they were assigned at birth). Your participation may help researchers better understand and support transgender and gender-diverse youth.
Richmond, VirginiaAges 15–21 - NCT05917977Recruiting
Motivational interviewing for teens with gaming problems
This study tests a talking program (called motivational interviewing) that helps teens aged 10-16 who struggle with too much gaming. The goal is to help them build motivation to change their gaming habits.
ShatinAges 10–16 - NCT05915377Recruiting
Screening for hospital confusion in older adults
This trial is testing practical ways to recognize delirium, a sudden type of hospital confusion, in older patients. It may help your care team spot confusion earlier and respond sooner.
Boston, MassachusettsAges 70 years+ - NCT05915013RecruitingPhase 1
Brain-targeting study of ketamine response in treatment-resistant depression
This early-stage study looks at how parts of brain cells respond to ketamine in people with depression who have not improved with usual antidepressants. It may help researchers find why ketamine works for some people and not others, and who might benefit.
New Haven, ConnecticutAges 18–60 - NCT05927974Recruiting
Brain mapping during surgery for hard-to-control epilepsy
This trial studies how the brain’s control networks work during a surgery-related procedure for people with epilepsy that hasn’t improved with usual treatments. If you qualify, you may do specific tasks while the team maps and measures brain activity to better understand and guide care.
Birmingham, AlabamaAges 18 years+ - NCT05916430Recruiting
Screening autism risk in 9-month-old infants
This trial checks how 8- to 10-month-old babies visually engage with people, which may help screen for autism risk earlier. It may help by improving early identification, especially for families who want screening done in a research setting.
Atlanta, GeorgiaAges 8 months–10 months - NCT05934474Recruiting
Study collects blood to learn about inflammation in mental illness
This study collects biological samples to better understand how “inflammation” in the body may relate to certain mental health conditions. Your results may help doctors learn more about causes and future treatments, even if the study does not give a new drug.
NantesAges 18 years+ - NCT05925322Recruiting
Social reward therapy for depression-related suicidal thoughts
This study looks at whether “social reward” psychotherapy can change brain activity and reduce suicidal thoughts in adults ages 50–80 who also have major depression. You may be offered psychotherapy along with brain scans to see how your brain responds over time.
New York, New YorkAges 50–80 - NCT05929677RecruitingEarly Phase 1
Study tests effects on impulsivity and how alcohol feels
This early-phase study looks at how alcohol affects impulsivity (tendency to act quickly) and people’s subjective experiences. You may be able to join if you drink regularly and meet the study safety rules.
Boston, MassachusettsAges 21–25
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.