Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05539807Enrolling by invitation
Mindfulness program for binge-eating symptoms
This study looks at whether a mindfulness approach can help reduce symptoms related to binge eating. You may be eligible if you’re 16 or older and feel your eating problems involve binge eating.
Bergen, BergenAges 16 years+ - NCT05511909RecruitingPhase 2
Buspirone study for opioid withdrawal symptoms
This Phase 2 study tests whether buspirone can help reduce symptoms during opioid detox (withdrawal). You may be able to take part if you have opioid withdrawal and are planning medically supervised detox.
Baltimore, MarylandAges 18–75 - NCT05530863Enrolling by invitation
Relaxation methods for insomnia during pregnancy
This study tests relaxation-based approaches to help pregnant people who have trouble falling asleep or waking up during the night. If you meet the sleep and pregnancy timing needs, the goal is to see whether the approach can improve sleep.
Philadelphia, PennsylvaniaAges 18–55 - NCT05540106Recruiting
Art therapy to reduce pain and anxiety in the ER waiting room
This trial studies whether guided art therapy can lower the pain and anxiety you feel while waiting to be seen in the emergency department. It may help you feel more calm and comfortable during the waiting time.
Stony Brook, New YorkAges 18 years+ - NCT05541406Recruiting
School support program for LGBTQ high school students
This trial is testing a program designed to make high schools more supportive for LGBTQ students. It aims to see if the program improves the school experience and well-being of LGBTQ youth.
El Monte, CaliforniaAges 12–20 - NCT05525702Recruiting
VR sessions to lower confusion in ICU patients
This trial tests whether virtual reality (VR) activities can reduce delirium—new, sudden confusion—in people staying in the ICU. It may help patients feel clearer and more oriented during a longer ICU stay.
Beijing, Beijing MunicipalityAges 18–90 - NCT05523817Recruiting
Brain scan targeting to improve specific depression symptoms
This study uses brain-signal targeting (likely with MRI) to see whether it can improve certain symptoms of depression. You may be able to join if you’re 18–65 and currently have a depressive episode, and if you can safely complete the scan.
Boston, MassachusettsAges 18–65 - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70 - NCT05548244Recruiting
Testing behavioral activation for teens with depression
This study looks at how a therapy approach called behavioral activation may affect depression in teens. It also uses brief daily check-ins on a phone to understand what changes during treatment.
Atlanta, GeorgiaAges 15–17 - NCT05514730Recruiting
Treatment program for harmful sexual behaviors in children
This trial offers a treatment program for preteen children whose caregiver reports concerning sexual behaviors. It aims to help reduce these behaviors and improve child well-being, with participation guided by language and caregiver involvement.
Harrisburg, PennsylvaniaAges 4–12 - NCT05537610Recruiting
Test a behavior strategy for frequent self-injury
This study looks at how to reduce serious problem behaviors (including self-injury) in children who have it many times per day even after previous treatment. It may help if your child’s behavior is driven by social attention or other positive effects and they can stay on the same supports, school plan, and medicines during the study.
Somerset, New JerseyAges 3–17 - NCT05541276RecruitingPhase 3
Melatonin to prevent waking confusion in young children after surgery
This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.
Copenhagen, Capital RegionAges 1–6 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT05515224Recruiting
Study for adults 65+ with memory concerns
This study looks at ways to help older adults with new or ongoing memory or thinking concerns. You may be able to take part if you’re 65 or older, have cognitive concerns, can complete study visits in English or Spanish, and are able to see and hear well enough for assessments.
Bloomington, IndianaAges 65 years+ - NCT05504681Recruiting
Using brain test markers in a cancer clinic visit
This study adds special brain “biomarker” tests into routine visits for adults with brain tumors. It may help the clinic better track these cancers over time and tailor care.
Miami, FloridaAges 18 years+ - NCT05515354RecruitingPhase 4
Smoking quit plan matched to your menstrual cycle phase
This Phase 4 study tests a smoking-quit treatment plan timed to your menstrual cycle. It may help you quit smoking and learn how quitting support works for people who menstruate regularly.
Toronto, OntarioAges 18–40 - NCT05509998Recruiting
Improving early care for untreated psychosis
This trial looks at ways to help people get treatment sooner after psychosis starts. It focuses on how screening and better communication across care teams may reduce the time before treatment begins.
New York, New YorkAges 12–30 - NCT05540704Recruiting
Therapy support for eating problems in type 1 diabetes
This study compares three groups: Acceptance and Commitment Therapy, standard supportive diabetes counseling, or a waitlist. It aims to reduce binge eating and harmful weight-control behaviors, including insulin withholding, in people with type 1 diabetes.
Durham, North CarolinaAges 16–50 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05515159Enrolling by invitation
Blood tests during electroconvulsive therapy
This study looks at blood markers (substances in blood) measured during electroconvulsive therapy, to understand how the treatment is working in the body. If you’re already being considered for ECT, you may be asked for blood samples as part of this research.
BergenAges 18 years+ - NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators
This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.
Iowa City, IowaAges 18 years+ - NCT05546554RecruitingPhase 2
Suvorexant for sleep problems in teens with autism
This Phase 2 study tests whether suvorexant helps improve sleep in children and teens with autism who have significant sleep trouble. It may help reduce behaviors related to poor sleep by changing how the brain promotes sleep.
Stanford, CaliforniaAges 13–17 - NCT05526196Recruiting
Study how cannabis and tobacco affect reaction and feelings
This study tests how cannabis and tobacco—used together or separately—affect your thinking speed, how you feel, and body responses. You may help researchers understand these effects under controlled conditions, which could be useful for safer use and treatment decisions.
Toronto, OntarioAges 19–45 - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.