Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05301361Enrolling by invitationPhase 1
Test of brain testing during stimulant treatment for ADHD
This trial checks whether a “NIH Toolbox” set of child-friendly tests can detect changes when stimulant medicine is used for ADHD. It may help doctors better measure how well stimulant treatment is working in people with intellectual disability.
Sacramento, CaliforniaAges 6–24 - NCT05301543Recruiting
Program to improve long-term insomnia symptoms
This study tests a behavioral (non-medication) program to help people with chronic insomnia sleep better. It may help if you regularly use sleep medications but still struggle with staying asleep or falling asleep.
Philadelphia, PennsylvaniaAges 55–85 - NCT05296356RecruitingPhase 2
Study drug for bipolar depression in people already on mood stabilizers
This trial tests whether OSU6162 can improve depressive symptoms in adults with bipolar depression who are already taking a stable mood-stabilizing medicine. It also checks safety by closely monitoring mood, heart rhythm, and other health factors during the study.
GothenburgAges 18–65 - NCT05296720Recruiting
EEG study of touch prediction in people with schizophrenia
This study uses a special brain test (EEG) while you do a touch-related task to see how your brain predicts what comes next. It may help researchers understand brain and behavior differences in schizophrenia and how sensory processing works.
StrasbourgAges 18–60 - NCT05283382RecruitingEarly Phase 1
Cannabidiol trial for learning and anxiety
This early-phase study tests how cannabidiol (CBD) affects learning and anxiety. You may be able to join if you meet age and health requirements and have not used CBD or other cannabis recently.
Storrs, ConnecticutAges 18–50 - NCT05268588Recruiting
Post-birth health texting study during late pregnancy
This study tests whether phone-based (mHealth) messages and support can improve health after you give birth. It may help you stay informed and get support during the weeks right after delivery.
Chandīgarh, HaryanaAges 18–49 - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05269459RecruitingPhase 2
Cannabidiol (CBD) for PTSD symptoms in adults
This study tests whether CBD, a non-psychoactive compound from cannabis, can help reduce symptoms of post-traumatic stress disorder (PTSD) in adults. If you have PTSD and are interested in a non-traditional treatment option, this might be worth exploring.
Omaha, NebraskaAges 21–65 - NCT05299814Recruiting
Study how parent emotion skills affect ADHD treatment
This study looks at whether helping parents manage their emotions can improve how their child with ADHD does. You may be asked to track emotions and behavior at home to better understand what supports work best.
Hershey, PennsylvaniaAges 5–12 - NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT05260177Recruiting
40 Hz light therapy for mild to moderate Alzheimer’s
This study tests whether a non-invasive 40 Hz light therapy system can help people with early Alzheimer’s. You’ll likely use the device at home and wear a small activity monitor, while doing memory and thinking tests.
RoskildeAges 40 years+ - NCT05304065RecruitingPhase 2
Safe program for suicidal thoughts or actions in youth
This Phase 2 study tests a safer way to support young people who recently had suicidal thoughts or acted on them. If you qualify, you may get the study treatment and support designed for teens and young adults after an urgent/emergency situation.
Los Angeles, CaliforniaAges 13–24 - NCT05289258Recruiting
Barlow-style program for thinking and memory problems after breast cancer
This trial tests a structured “Barlow Protocol” program to help improve mild to moderate thinking and memory problems in people who finished breast cancer chemotherapy. It may help if your cognitive symptoms started after treatment and you’re not already in similar therapy.
CórdobaAges 18–70 - NCT05294042Recruiting
Patient navigators for children’s mental health care
This study tests a support program that helps children and caregivers find and get community mental health services, especially in high-poverty areas. It may help by making it easier to connect with the right services and stay engaged while waiting or starting care.
Chicago, IllinoisAges Up to 14 years - NCT05307432Enrolling by invitation
Telehealth safety planning after an ER visit for suicide risk
This study tests a phone/video-based “safety plan” service for adults after an ER visit related to suicide risk. It may help you (or the ER team) feel more prepared to stay safe and know what to do next after you leave the hospital.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05282277RecruitingPhase 4
Estradiol to improve brain and reward changes in midlife women
This study tests whether a hormone called estradiol (given as a patch and pill) changes how the brain and body respond to reward in some midlife women with low pleasure and/or psychosis symptoms during menopause transition. It may help researchers understand whether estrogen treatment can improve mood-related “reward” function in this group.
Chapel Hill, North CarolinaAges 45–55 - NCT05310097Recruiting
CPT therapy program with memory support for PTSD veterans
This study tests a counseling approach called Cognitive Processing Therapy (CPT) with added memory support tools. It may help reduce PTSD symptoms while also supporting day-to-day memory challenges common in PTSD.
Jamaica Plain, MassachusettsAges 18 years+ - NCT05292612Recruiting
Coach vs clinician self-help for social anxiety
This trial tests whether two different self-help programs (one guided by a coach and one by a clinician) can improve generalized social anxiety. You may be able to use an evidence-based approach at home, with the goal of reducing fear and avoidance in social situations.
ShatinAges 18–100 - NCT05276050Recruiting
Brain-circuit treatment to help people with schizophrenia quit smoking
This study tests a circuitry-guided approach to help people with schizophrenia quit smoking. It may help reduce cravings and improve quitting, while also watching for safety issues.
Houston, TexasAges 22–65 - NCT05292794Recruiting
CereGate therapy for freezing of gait in Parkinson’s
This trial tests whether CereGate therapy can reduce “freezing of gait,” a walking problem, in people with Parkinson’s disease who already have deep brain stimulation (DBS). If you meet the device and medication stability requirements, the study may help your walking and movement symptoms measured during testing.
Redwood City, CaliforniaAges 21–80 - NCT05295615Recruiting
Pulsed magnetic treatment for mild to moderate Alzheimer’s
This trial tests whether a pulsed electromagnetic field (a non-drug device that uses magnetic pulses) can help people with mild to moderate Alzheimer’s. Participants typically stay on stable Alzheimer’s medicines and follow daily home treatments during the study.
Hackensack, New JerseyAges 50–100 - NCT05303064RecruitingPhase 3
Study of weight gain medicine for teens with certain mood or psychosis
This Phase 3 study tests a treatment aimed at reducing unhealthy weight gain in teens with schizophrenia or bipolar I disorder, using changes in BMI (a height-and-weight measure). It may help families who are concerned about weight changes that can happen with some psychiatric medicines.
Dothan, AlabamaAges 10–17 - NCT04583800Recruiting
Tracking heart failure risk and memory change in diabetes
This study follows adults with type 2 diabetes to see who may develop heart problems and who may have memory or thinking changes over time. It may help doctors better predict risk and plan earlier support.
LilleAges 18 years+ - NCT04727489Recruiting
Study genes in autism and related conditions using blood samples
This study looks for genetic reasons for autism by collecting blood samples from people with autism, people without autism, and their relatives. The results may help researchers better understand causes and risk factors, even if you only participate through testing a sample.
Grenoble, GrenobleAges 2–70
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.