Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,784 recruiting studies in this area right now.
By phase
- Not applicable6,423
- Phase 2495
- Phase 1249
- Phase 3240
- Phase 4214
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress118
- PTSD104
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development102
- Yale University87
- Massachusetts General Hospital79
- Stanford University69
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts269
- New York254
- Texas209
- Maryland175
- Pennsylvania170
- Florida148
- Alabama119
- Arizona111
- Ohio104
Recruiting studies7,784 total
- NCT02914951Enrolling by invitation
Therapy to reduce irritability in children with autism
This trial studies whether cognitive-behavioral therapy (a structured talk therapy) can reduce irritability and anger outbursts in children with autism. It may help improve day-to-day behavior by teaching coping skills and reducing problem reactions.
New Haven, ConnecticutAges 8–16 - NCT02972008Recruiting
Looking for blood markers that predict complications after TAVI
This study enrolls older adults having a minimally invasive heart valve procedure (TAVI) to find “epigenetic” risk markers—signals in the body that may predict who is more likely to have complications during the procedure. If you qualify, your blood and/or samples may be studied to improve safety for future patients.
LilleAges 70 years+ - NCT02878408Recruiting
Study of immune and genetics factors in bipolar or schizophrenia
This study looks at how the immune system, genetics, inflammation, and past exposures may relate to bipolar disorder or schizophrenia. It may help researchers understand the cause and find better ways to support people with these conditions.
Créteil, FranceAges 16 years+ - NCT02740634Recruiting
Brain imaging study for Alzheimer's disease
This study uses brain scans to understand Alzheimer's disease and related conditions that affect memory, language, or vision. It looks at how changes in the brain happen over time in people with these diagnoses.
Rochester, MinnesotaAges 21–80 - NCT02726061Recruiting
Online psychological support for depression
This study tests an internet-based (online) psychological support program for adults who are feeling depressed. It may help participants by offering structured support without needing in-person visits.
Lebanon, New HampshireAges 18 years+ - NCT02911090Enrolling by invitation
Register your endometriosis or pelvic pain information
This trial is a patient registry that collects information from people seen at a specialized clinic for endometriosis and chronic pelvic pain. Sharing your questionnaire helps the team better understand symptoms and care needs over time.
Vancouver, British ColumbiaAges Any age - NCT02811653Recruiting
Brain movement and memory study in early dementia
This study looks at how “slower movement” and brain changes relate to memory and thinking problems in people with early dementia (and some related conditions). It may help researchers understand what brain differences go with these symptoms, using tests and an MRI scan.
AmiensAges 40–85 - NCT02763683Recruiting
Study brain changes in Parkinson-related dementia
This study looks at brain features linked to dementia in people who have Parkinson disease. It may help researchers understand why dementia happens in Parkinson and how it could be detected or treated in the future.
St Louis, MissouriAges 50 years+ - NCT02688959Recruiting
Motor attention training for ADHD in university students
This study tests whether a structured training program can improve attention and focus in people with ADHD. It is designed for students enrolled at the University of Wisconsin–Madison who already have an ADHD diagnosis.
Madison, WisconsinAges 18–23 - NCT02916810Recruiting
TMS for persistent auditory hallucinations using a new setup
This study tests a specific brain stimulation approach (TMS) to help reduce auditory hallucinations in adults with schizophrenia who have not improved enough with medications. It may help by changing how the brain regions involved in hearing voices are stimulated.
Houston, TexasAges 18–50 - NCT02543983RecruitingPhase 2
Brain scan and ketamine study for suicidal thoughts
This trial studies how ketamine affects the brain in people dealing with suicidal thoughts or an active suicide crisis. It uses questionnaires, consent testing, and brain imaging to look for biological changes that may relate to symptom improvement.
Bethesda, MarylandAges 18–70 - NCT02231840Recruiting
Study of how alcohol use changes over time
This study follows people over time to understand how alcohol use develops and changes. It may help researchers learn what factors are linked to changes in drinking, and it involves genetic testing and an MRI scan.
Bethesda, MarylandAges 18–100 - NCT02531893Recruiting
Therapy for youth with severe, frequent irritability
This study tests whether two structured therapies can reduce severe irritability and angry reactions in children and teens. It focuses on youth who have had long-lasting, frequent outbursts and trouble responding to negative emotions.
Bethesda, MarylandAges 8–17 - NCT02414347Recruiting
Tau PET scan study for Alzheimer’s disease
This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.
St Louis, MissouriAges 18 years+ - NCT02414178Enrolling by invitation
Tau PET brain scan for inherited Alzheimer’s disease
This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.
St Louis, MissouriAges 18 years+ - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT02455479RecruitingPhase 1
Safety study of a vaccine for cocaine dependence
This early-stage study tests how safe an experimental “cocaine vaccine” is and how the body reacts to it. You must also be in behavioral therapy, and the study aims to see whether the vaccine can be given safely to people with cocaine use disorder.
New York, New YorkAges 21–69 - NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT02300766Recruiting
Study of cerebellar mutism in children with brain tumors
This study looks at how children with certain brain tumors develop “cerebellar mutism” after surgery or an open biopsy. The goal is to better understand the syndrome and what might help support recovery.
ViennaAges Up to 18 years - NCT02560805RecruitingPhase 2
Study drugs that affect stress nerves and blood pressure in PTSD
This Phase 2 study looks at how stress-related nerve activity and a hormone called angiotensin II may be involved in PTSD, and how specific blood-pressure-related medicines affect the body. You may be eligible if you are a PTSD patient (or a matched control without PTSD) and meet safety criteria.
Decatur, GeorgiaAges 18–65 - NCT02564692Enrolling by invitation
APOE gene testing registry to find Alzheimer’s prevention studies
This program enrolls people to get a gene test (APOE) so researchers can match you to Alzheimer’s prevention studies in the future. If you qualify, you do the test but you would not receive your gene test results.
Phoenix, ArizonaAges 50–90 - NCT02447861Recruiting
Study of behavior differences in 3q29 deletion or duplication
This study looks at how brain development and behavior may differ in people with a 3q29 deletion or 3q29 duplication. It may help researchers understand what to expect and how these conditions affect daily life.
Piscataway, New JerseyAges Any age - NCT02670447Recruiting
Checking new support for a first psychosis, no prior medication
This trial looks at people having a first psychotic episode who have not yet taken anti-psychotic medicine. It aims to see whether an early support approach can help, before other treatments become necessary.
BronAges 18–35
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,784 recruiting psychiatry studies from the U.S. registry right now, out of 12,489 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.