Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT07200531Recruiting
Can therapy change gut bacteria in women?
This trial studies whether psychotherapy can affect the bacteria living in your gut. It is for women aged 19 to 53 who are not pregnant, breastfeeding, or already in regular therapy.
Omaha, NebraskaAges 19–54 - NCT07198438Enrolling by invitation
Deep vs standard brain stimulation for depression
This trial compares two types of brain stimulation (deep vs standard theta burst stimulation) to see which works better for people with depression who haven't gotten enough help from antidepressant medication. It aims to find a more effective treatment option.
Douliu, Yunlin CountyAges 18–70 - NCT06543732Recruiting
Return to work program for stress-related sick leave
This study tests a program called Vital@Work that helps employees who are on sick leave due to stress to return to work. If you have been off work for 2 to 12 weeks because of stress, this program might support your recovery and reintegration.
AmsterdamAges 18–68 - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+ - NCT06050304Recruiting
Crack cocaine use and behavioral sensitization study
This study looks at how your body and mind might get more sensitive to crack-cocaine over time (behavioral sensitization) and what you expect from using it. Your participation helps us better understand addiction patterns.
ParisAges 18 years+ - NCT05785169Recruiting
Trial improves clinic support for people with HIV
This study works with specific Ryan White clinics to improve support and well-being for both patients and healthcare staff. It will help test whether an “all-facility” approach in participating clinics can create a better care experience.
New York, New YorkAges 18 years+ - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90 - NCT07195890Enrolling by invitation
Teen Mental Health First Aid for Hong Kong students
This trial tests whether a Teen Mental Health First Aid course helps students in Hong Kong secondary schools better support peers with mental health struggles. It is for students in Forms 4–6 whose schools are already offering the course.
Hong Kong, HksarAges 14–18 - NCT06871982Enrolling by invitation
Norms re-education for parent involvement in college
This study tests a program called Norms Re-education that helps parents get involved in supporting their college students. It is for new first-year students at LMU or Lehigh University and their parents.
Los Angeles, CaliforniaAges 17–20 - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT06575751RecruitingPhase 2
Study of cannabidiol and cannabis concentrate users
This study looks at how cannabidiol (a compound in cannabis) affects people who regularly use strong cannabis concentrates like wax, shatter, or oil. It may help understand if using CBD can change how cannabis affects the body or help with cannabis use disorder.
Aurora, ColoradoAges 25–60 - NCT07191782Recruiting
Testing the PRAISE with Coaching Program in Schools
This study tests a program called PRAISE that helps teachers support students' social and emotional skills. It may help your child feel more connected and do better in school.
Philadelphia, PennsylvaniaAges 8 years+ - NCT06047041Recruiting
School mental health support trial for middle schools
This trial tests a program to help middle schools improve how they identify and support students' mental health. It may help schools better connect students with the right services.
Columbia, MissouriAges 10–99 - NCT07190365Recruiting
Goal-oriented telehealth rehab for veterans with brain injury
This trial tests a telehealth program to help veterans with long-term thinking and planning problems after a mild to moderate brain injury. It aims to improve your daily life and community involvement.
Palo Alto, CaliforniaAges 18–65 - NCT07188467Recruiting
Stress and well-being support for international students
This study tests a self-help program called 'SH+' designed to reduce stress and improve well-being in international students at The New School. If you are an international student feeling at least mildly distressed, this program may help you develop coping skills.
Brooklyn, New YorkAges 18 years+ - NCT07418437Enrolling by invitation
Loneliness help for cancer survivors
This study tests a program to help reduce loneliness in people who have had cancer. You may be able to join if you often feel lonely and are not currently in a hospital or nursing home.
Seattle, WashingtonAges 18 years+ - NCT05788198Recruiting
Care plan support for people with depression symptoms
This study tests an integrated care approach (case management) for adults with depression symptoms who are first seen by their regular doctor. It may help by making it easier to get the right support and follow-up.
MechelenAges 18–65 - NCT06545968Recruiting
Social media to help young people with HIV stay in care
This study tests whether a social media program can help young people with HIV in Uganda stay connected to their medical care. If you are between 15 and 24 years old and are new to care or returning after a break, you may be able to join.
MbararaAges 15 years+ - NCT06547008RecruitingPhase 1
Suicide prevention training for army leaders
This study tests a suicide prevention training program for unit leaders and chaplains in the Connecticut Army National Guard. It aims to see if the training helps them better support soldiers in need.
Hartford, ConnecticutAges Any age - NCT07180108Enrolling by invitationPhase 1
Psilocybin and music study for healthy volunteers
This study tests how music affects your experience with psilocybin, a psychedelic substance. It may help researchers understand how to create the best setting for psilocybin therapy.
Baltimore, MarylandAges 21–75 - NCT07092345Recruiting
Helping youth connect to community care after an ER visit
This study tests a program to help youth who come to the emergency room for suicidal thoughts or self-harm. It aims to connect them and their families with support services in the community after they leave the hospital.
Providence, Rhode IslandAges 8–17 - NCT07167641Recruiting
Support for parents and caregivers of young people with psychosis
This study focuses on supporting parents and caregivers of young people who have had a first episode of psychosis. The goal is to understand how to help you while you care for your loved one. If you’re a caregiver connected to a UNC Coordinated Specialty Care program, you may be able to join.
Chapel Hill, North CarolinaAges 18–99 - NCT07163013Recruiting
Digital therapy for teens with depression
This trial tests a digital therapy (a phone- or computer-based program) that teaches you skills to manage depression. It is designed for Chinese-speaking teens who have moderate to severe depression and are not currently receiving other treatment.
ChongqingAges 12–18 - NCT06551038Recruiting
Suicide prevention program for at-risk teens
This study tests a new program to help prevent suicide in teens and young adults who face extra challenges. It is designed for those who are already struggling with mental health, school, detention, or other tough life situations.
Geneva, Canton of GenevaAges 14–25
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.