Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,199 recruiting studies in this area right now.
By phase
- Not applicable6,804
- Phase 2511
- Phase 1256
- Phase 3244
- Phase 4214
- Phase 1/Phase 298
- Phase 2/Phase 372
Top conditions
- Depression419
- Anxiety411
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia227
- Mild Cognitive Impairment201
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia154
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders83
Leading sponsors
- VA Office of Research and Development104
- Yale University96
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California528
- New York267
- Massachusetts261
- Texas224
- Maryland176
- Pennsylvania174
- Florida154
- Alabama118
- Arizona117
- Connecticut114
Recruiting studies8,198 total
- NCT05548244Recruiting
Testing behavioral activation for teens with depression
This study looks at how a therapy approach called behavioral activation may affect depression in teens. It also uses brief daily check-ins on a phone to understand what changes during treatment.
Atlanta, GeorgiaAges 15–17 - NCT06865833Recruiting
Non-drug methods to help teens with somatoform disorders
This trial tests if activities like Tai Chi can help teens aged 12-19 who have physical symptoms caused by stress or emotions (somatoform disorders). You would join a group to try these methods and see if they make you feel better.
Créteil, CréteilAges 12–19 - NCT07271953Recruiting
Help for new moms to stay smoke-free after pregnancy
This trial tests if motivational interviews and a digital game can help women who quit smoking early in pregnancy avoid restarting after giving birth. You will receive support through counseling and a game to stay smoke-free.
Ankara, AnkaraAges 18 years+ - NCT07132814Recruiting
Testing abuse potential of five oral nicotine products
This study tests how much people might want to use five different types of modern oral nicotine products (like pouches or lozenges) compared to smoking their usual cigarette. It helps researchers understand if these products could be less addictive than cigarettes.
Overland Park, KansasAges 21–60 - NCT06957392Recruiting
Study on gaming and social rewards in internet gaming disorder
This trial looks at how social rewards affect thinking and control in people with internet gaming disorder. It may help find better ways to help those who spend a lot of time playing Honor of Kings.
BengbuAges 18–35 - NCT06557642Recruiting
Laughing Gas and Emotional Thinking Study
This study tests how nitrous oxide (laughing gas) affects your emotions and thinking. It's looking for healthy volunteers ages 18 to 40 to see how the gas might change emotional processing.
OxfordAges 18–40 - NCT06854562Recruiting
Therapeutic robots to reduce stress for kids in the ICU
This study tests whether friendly robots can help children aged 8 to 18 feel less stressed while they are in the intensive care unit (ICU). If your child is awake, able to respond, and speaks Mandarin or Taiwanese, they may be able to participate.
Taipei, Beitou DistrictAges 8–18 - NCT07118072Recruiting
Online therapy for childhood trauma and depression symptoms
This study will test if a special online therapy program, called i-STAIR, can help people who had a tough childhood and are now dealing with some depression symptoms. It focuses on building skills to manage emotions and relationships, all from the comfort of your home.
SingaporeAges 21–65 - NCT06817993Recruiting
How social media affects the teen brain
This study looks at how social media affects the brains of teens with depression. You would complete smartphone surveys and have one brain scan (MRI) to help researchers understand these connections.
Pittsburgh, PennsylvaniaAges 13–17 - NCT07074704Enrolling by invitation
Brain stimulation to improve symptoms and thinking in schizophrenia
This study tests whether a gentle electrical current applied to the scalp (transcranial alternating current stimulation, or tACS) can help reduce negative symptoms and improve thinking in people with long-term schizophrenia. It is for patients who have been hospitalized for over six months and are on stable medication.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06828887RecruitingPhase 2
Testing LV232 capsules for major depression
This trial tests a new medicine called LV232 for people with moderate to severe depression. Researchers want to find the best dose and check if it works safely.
ShanghaiAges 18–65 - NCT07105033Recruiting
Focused ACT for advanced cancer patients
This study tests a counseling program called Focused ACT (FACT) to help patients with advanced cancer cope with stress and death anxiety. It involves talking with a counselor about important areas of your life.
Houston, TexasAges 18 years+ - NCT07104474Enrolling by invitation
RESTORE trial for nurses and hospital leaders
This trial is testing a program called RESTORE to help nursing staff and hospital leaders improve patient care. It aims to see how well the program works and how it can be used in different hospitals.
Madison, WisconsinAges 18 years+ - NCT05981612Recruiting
How emotions affect decision-making in teens who self-harm
This study looks at how strong emotions affect decision-making in teenagers who sometimes hurt themselves without wanting to die (called NSSI). If you join, you'll have an MRI brain scan and do some computer tasks to help us understand this link.
Chengdu, SichuanAges 15–18 - NCT06886165Recruiting
New therapy for teens with multiple life problems
This trial tests a new therapy called AMBIT (Adaptive Mentalization-based Integrative Treatment) to help teens facing multiple challenges. It compares the new therapy to the usual care to see if it works and is practical.
Roskilde, Region SjællandAges 12–17 - NCT06565936Recruiting
PET/MRI brain scans for understanding depression
This trial uses two special brain scans (DPA-714 and FDG PET/MRI) to look at inflammation and brain activity in people with first-episode or recurrent depression, and in healthy volunteers. It aims to find brain differences that could lead to better treatments.
Dalian, LiaoningAges 35–85 - NCT06858540Recruiting
Blended therapy for teens who self-harm
This trial tests a type of talk therapy to help teens who have hurt themselves on purpose (non-suicidal self-injury). It mixes in-person sessions with online tools to teach better coping skills and reduce self-harm.
Changsha, HunanAges 12–17 - NCT07091877Recruiting
Cocaine use and brain response study
This study looks at how cravings for cocaine change over time in people who have recently stopped using. Researchers will measure brain activity to understand this process better.
New York, New YorkAges 18–65 - NCT07086794RecruitingEarly Phase 1
Testing if pentoxifylline helps reduce cocaine use
This study tests whether a medication called pentoxifylline can reduce cocaine use in people who smoke or inject cocaine but aren't ready to stop. You'll receive either pentoxifylline or a placebo to see if it helps control cravings or use.
Lexington, KentuckyAges 18–55 - NCT07080736Recruiting
Online suicide prevention training for prison staff
This trial tests an online course (e-learning) to help professionals working in prisons learn how to prevent suicide. The goal is to see if the training improves knowledge and skills for supporting people at risk.
GhentAges 18 years+ - NCT07278934Recruiting
Family program to help teen girls thrive in school and health
This study tests a family-based program to help adolescent girls who have been skipping school. The goal is to improve their school attendance, development, and overall health.
TamaleAges 11 years+ - NCT06801925Enrolling by invitation
Voice Chatbot for Depression Screening
This trial tests a voice chatbot that uses artificial intelligence to screen for depression. It aims to see if the chatbot is effective and easy to use.
LondonAges 18–65 - NCT07064551Recruiting
Combining medical and community support for depression
This study tests a new way of combining medical care with community support for middle-aged and older adults who have depression and are waiting for mental health services. The goal is to see if this team approach can help improve mood and well-being while you wait.
Hong KongAges 45 years+ - NCT07294482Recruiting
Reishi liquid extract for better sleep
This study tests a liquid Reishi mushroom extract (a supplement) to see if it helps improve sleep quality. It is for healthy adults who are not pregnant, nursing, or taking certain medications.
New York, New YorkAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,199 recruiting psychiatry studies from the U.S. registry right now, out of 13,332 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.