Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07100613RecruitingPhase 2
Mouth film for treating oral lichen planus
This trial tests a new sticky mouth film that slowly releases medicine to treat painful sores from oral lichen planus. It may help people who have not been treated before for this condition.
Palermo, ItalyAges 18 years+ - NCT07098325Recruiting
3d printed retainers for braces after treatment
This trial tests how your mouth reacts to a 3d printed retainer after braces. It may help you keep your teeth straight.
AsyutAges Any age - NCT07101744RecruitingPhase 2
Drug combination study for advanced nasopharyngeal cancer
This trial tests a combination of three drugs for people with nasopharyngeal cancer that has come back or spread and stopped responding to first-line chemotherapy. It aims to see if this new combination can help when standard treatment no longer works.
GuangdongAges 18–70 - NCT06363721Recruiting
Testing an oil rinse for plaque and gum health
This study tests a special oil rinse called PerioPull™ to see if it improves dental health. You may be able to join if you have plaque buildup, bleeding gums, and no deep gum pockets.
Ellicott City, MarylandAges 18 years+ - NCT06356246Recruiting
Oral health survey for adults with cystic fibrosis
This study uses an online survey to learn about the oral health of adults with cystic fibrosis. Your answers can help doctors understand and improve dental care for people like you.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT07088055Recruiting
Chewing device vs. oral motor therapy for jaw alignment in kids
This study tests whether a special chewing device (Myo Munchee) can help improve jaw alignment and muscle function in children ages 3–5 who have both jaw alignment problems and orofacial myofunctional disorders. It compares the device to standard oral motor therapy.
Chicago, IllinoisAges 3–5 - NCT07090551Recruiting
Mouthguard for jaw and neck muscle pain from grinding
This study tests whether a custom mouthguard (occlusal splint) can reduce pain and tension in the jaw and neck muscles. It is for people with bruxism (teeth grinding) and myofascial pain, a type of muscle pain in the jaw area.
IstanbulAges 18–50 - NCT07091422Recruiting
Testing a new brace glue: does it hold better?
This trial tests a new no-etching glue for braces. Half of your mouth will get the new glue, the other half a standard glue, to see which one holds the brackets better over a year.
Baltimore, MarylandAges 14–35 - NCT07088172Recruiting
Gum graft timing for dental implants in the lower back jaw
This trial compares two different times to do a gum graft around a dental implant in the lower back jaw. It aims to find out which timing works better for patients who don't have enough thick gum tissue (less than 2 mm).
Hangzhou, ZhejiangAges 18 years+ - NCT07085988RecruitingPhase 2
Nutrition help for nasopharyngeal cancer patients on chemoradiation
This trial tests if special nutritional management during concurrent chemoradiotherapy can improve outcomes for people with nasopharyngeal cancer. If you are getting both chemotherapy and radiation as your main treatment, this study may help you maintain better nutrition.
Nanchang, JiangxiAges 18 years+ - NCT07090772Enrolling by invitation
Comparing jaw position methods for splint therapy in TMJ disc displacement
This trial tests different ways to determine the best jaw position for a mouth splint used to treat a specific type of temporomandibular joint (TMJ) problem where the disc is out of place and doesn't go back. The goal is to see which method works better for reducing pain and improving jaw function.
Fuzhou, FujianAges 13–50 - NCT07093749Recruiting
Antibiotics and symptom tracking in children
This study looks at how children with common infections feel while taking antibiotics. The goal is to better understand symptom patterns during treatment.
Melbourne, VictoriaAges 4–17 - NCT07091448RecruitingPhase 4
Membrane for preserving bone after tooth removal
This study tests a special membrane placed in the tooth socket after a back tooth is removed, to help preserve the bone before getting a dental implant. It may help keep the area strong for the implant.
Baltimore, MarylandAges 18 years+ - NCT07088679Recruiting
Natural gel for dental implant gum disease
This trial tests a natural gel to treat gum disease around dental implants. It may help reduce bleeding and bone loss around implants.
Pavia, LombardyAges 18–70 - NCT07095608Recruiting
Study on nerve cells and oral cancer pain
This study looks at how certain nerve cells might be involved in oral cancer pain. It aims to find new ways to treat pain by testing tissue samples from people with oral cancer and healthy volunteers.
New York, New YorkAges 18 years+ - NCT07095374Enrolling by invitation
How jaw widening affects premolar tilt
This study looks at how widening the upper jaw with a special device (rapid palatal expander) affects the tilt of certain teeth (premolars). It may help doctors understand how to plan better orthodontic treatments.
Pavia, LombardyAges 6–14 - NCT07088809Enrolling by invitation
Nanoparticles with Platelet-Rich Fibrin for Gum Recession
This trial tests a new material to treat gum recession—tiny particles mixed with your own blood components (platelet-rich fibrin) placed as a membrane. The goal is to see if it helps cover exposed roots and improve gum health.
Tanta, Gharbia GovernorateAges 20–45 - NCT07094581Recruiting
How adenoid size affects chewing muscle in children
This study uses ultrasound to see if enlarged adenoids affect the masseter muscle (a chewing muscle) in children. It may help doctors understand how breathing problems during sleep or mouth breathing impact jaw muscles.
Aydin, EfelerAges 3–8 - NCT07095556Recruiting
Laser therapy to help gums heal after tooth extraction
This trial tests whether a special laser treatment can help your gums heal better after a tooth is removed and the socket is prepared for a future dental implant. If you're having a tooth pulled and bone preservation, this laser might speed up healing and reduce pain.
Charleston, South CarolinaAges 18 years+ - NCT07090694Enrolling by invitationPhase 1
Sinus lift with or without platelet-rich fibrin for dental implants
This trial compares two ways to place dental implants in the upper jaw where there is not enough bone: one uses a special clotting substance (PRF) and the other does not. The goal is to see which method works better.
RiyadhAges 25–65 - NCT06974253Recruiting
Guided Implant Placement for Full Upper Jaw
This study tests a technology that uses a computer-guided system (dynamic navigation) to place multiple implants in the upper jaw of people who have no teeth left. It aims to improve placement accuracy and make the surgery safer.
Ho Chi Minh CityAges 18 years+ - NCT04040920Recruiting
Ozone treatment before dental sealants
This trial tests whether applying ozone to certain back teeth before placing sealants helps the sealants work better. You might qualify if you need sealants on specific molars and can safely have the area isolated during treatment.
Trieste, TriesteAges 6–16 - NCT06347679Recruiting
Can aromatherapy ease anxiety and pain during dental work?
This study tests whether smelling certain essential oils (aromatherapy) can help reduce anxiety and pain during dental treatments. If you are an adult having a dental procedure, this may be a way to feel more comfortable without medication.
Chengdu, SichuanAges 18–40 - NCT06975709Recruiting
Link between jaw pain and sleep problems
This study looks at how jaw joint disorders (TMJ) are related to sleep issues like insomnia, sleep apnea, or restless legs. If you have a sleep disorder, you may help researchers understand the connection.
Milan, ItalyAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.