Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,543
- Phase 2144
- Phase 385
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Florida21
- Maryland21
- Massachusetts21
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06791694Enrolling by invitation
Comparing tooth color measurement methods for dental students
This trial tests different ways to measure tooth color in healthy young adults. It aims to see which method works best for dental students to learn.
Altındağ, AnkaraAges 18–40 - NCT06787456Recruiting
Screening for nasopharyngeal cancer in residents
This study is screening residents aged 30-69 for nasopharyngeal cancer (NPC). It aims to detect cancer early through regular check-ups and follow-up.
Zhuhai, GuangdongAges 30–69 - NCT06782165Recruiting
Long-term follow-up of jaw joint surgery
This study follows up on patients who had jaw joint (TMJ) surgery. It looks at how the joint is doing after 6 months to predict long-term results. It may help understand if earlier checkups can guide care.
HuddingeAges 18 years+ - NCT06782178Recruiting
Comparing two jaw joint procedures for limited mouth opening
This study compares two minimally invasive procedures (arthroscopy using a tiny camera vs. arthrocentesis using a needle to flush the joint) to see which works better for people with a displaced jaw disc that limits mouth opening. It might help you if simple treatments haven't worked.
HuddingeAges 18 years+ - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06782191Recruiting
Arthroscopic treatments for jaw joint disc displacement
This trial tests two types of jaw joint surgery for people with a displaced disc that still moves. It compares a simpler procedure (flushing the joint) with a more involved one (surgical repair) to see which helps more with pain and jaw function.
HuddingeAges 18 years+ - NCT06788002RecruitingPhase 2
Low-dose radiation and chemoimmunotherapy for NPC with liver spread
This trial tests a combination of low-dose radiation, chemotherapy, and immunotherapy for nasopharyngeal cancer that has spread to the liver. It aims to see if this approach can help shrink tumors and improve outcomes.
Changsha, HunanAges 18–70 - NCT06773923Enrolling by invitationPhase 3
3D-printed bone scaffold trial for dental implants
This trial tests a 3D-printed scaffold that dissolves over time to help regrow jawbone for dental implants. It is for people in Valdivia, Chile, who need bone buildup in the lower jaw.
ValdiviaAges 30–70 - NCT06776653Recruiting
Snoezelen for anxiety during dental care
This trial tests whether adding a calming Snoezelen element to dental care reduces anxiety. It is for adults who can share their feelings during treatment.
Nantes, NantesAges 18 years+ - NCT06780462RecruitingPhase 3
Steroids with or without blood thinners for Behçet's vein clots
This trial tests whether adding a blood thinner (anticoagulant) to steroid therapy is more effective than steroids alone for treating deep vein thrombosis (a blood clot in a large vein) in people with Behçet's syndrome. It aims to find the best way to prevent future clots and reduce side effects.
BordeauxAges 18 years+ - NCT06775717Enrolling by invitation
Mirror and imagination exercises for Bell's palsy recovery
This study tests whether practicing facial movements in your imagination (motor imagery) combined with mirror exercises can help reduce unwanted facial movements (synkinesis) and improve facial symmetry and quality of life in people with new Bell's palsy. You would learn simple exercises to do at home with a mirror and guidance.
Sialkot, Punjab ProvinceAges 18 years+ - NCT06776640Recruiting
Vitamin D3 before dental implant surgery for better bone bonding
This trial tests whether taking vitamin D3 pills before and after dental implant surgery helps the implant bond better with the bone. It is for people who have low vitamin D levels and are already scheduled for an implant.
Nantes, NantesAges 18 years+ - NCT06761521Enrolling by invitation
Monitoring implant health with aMMP-8 test
This study uses a special test to check for inflammation around dental implants. It may help catch problems early and is for people who already have implants.
Helsinki, UusimaaAges Any age - NCT06768424Recruiting
Treating deep gum pockets with laser or scalpel and platelet gel
This study compares two ways to fix deep gum pockets around teeth: a laser (MIST) or a traditional scalpel (GBT). Both methods use a gel made from your own blood (PRF) to help healing. The goal is to see which works better.
Budapest, BudapestAges 18–65 - NCT06767670Recruiting
Oral hygiene and germs in kids' mouths with two types of crowns
This study looks at how different types of ready-made crowns for baby molars affect the number of germs in a child's mouth and how oral hygiene plays a role. It might help dentists choose the best crown for kids.
Cairo, Nasr CityAges 4–8 - NCT06763640Enrolling by invitation
TILs as a predictor in nasopharyngeal cancer
This study looks at how immune cells called TILs (tumor-infiltrating lymphocytes) in your tumor tissue might predict outcomes for nasopharyngeal cancer. It may help doctors better understand your cancer and guide future treatment decisions.
Nanchang, JiangxiAges 18–70 - NCT06760442Recruiting
Dental implant placement: even with the bone vs slightly below
This trial compares two ways of placing a dental implant in the jawbone to see which leads to less bone loss around the implant. It may help if you are missing a back tooth and have enough jawbone after a bone graft.
CairoAges 21–60 - NCT06290661Recruiting
Nerve stimulation for shingles-related nerve pain
This study tests a treatment called peripheral nerve stimulation (using a small device to send mild electrical pulses) for people with nerve pain after shingles. It's designed for those whose pain is not well managed by usual treatments.
Wuhan, HubeiAges 18 years+ - NCT05894070Recruiting
Using your voice recordings to spot cancer coming back
This study looks at whether changes in your voice can help detect early return of laryngeal or hypopharyngeal cancer. If you’ve finished curative treatment and are disease-free for a certain period, your voice will be monitored to see if it can signal recurrence sooner.
BernAges 18 years+ - NCT06753669Recruiting
Mothers' action project for child health
This study looks at how to help mothers from South Asian communities support their child's health and development. You and your child would join a program that provides guidance and resources over 12 months.
New York, New YorkAges 1–45 - NCT06753396Recruiting
Effect of injectable platelet-rich fibrin on gum tissue around dental implants
This trial tests whether a treatment made from your own blood (injectable platelet-rich fibrin) can help improve thin or narrow gum tissue around dental implants. It may be an option if you have less than 2 mm of gum width or thickness around your implant.
KütahyaAges 18 years+ - NCT06753305Recruiting
Ozone therapy for gum reshaping after inflammation
This study tests if ozone therapy helps heal gums after reshaping surgery for overgrown gum tissue caused by inflammation. It may reduce recovery time or improve results.
KütahyaAges 18 years+ - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Avondale, ArizonaAges 18 years+ - NCT05821075RecruitingPhase 1/Phase 2
Prednisolone vs Cerebrolysin for sudden facial weakness
This early-stage study compares two medicines—prednisolone and cerebrolysin—to see which works better for Bell’s palsy (sudden one-sided facial weakness with no clear cause). You may be asked to take one of the study treatments and be followed to measure how well facial movement improves.
GizaAges 18–60
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,756 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.