Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT05859997Enrolling by invitation
CAR-T cell therapy for active autoimmune disease flare-ups
This study tests an immune-cell treatment (CAR-T, called BRL-301) in people with certain autoimmune diseases that are active and hard to control. It may help your immune system calm down if standard treatments have not worked or your disease has returned.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05814991Enrolling by invitation
Study of factors affecting operating field visibility in jaw surgery
This study looks at what makes the surgeon’s view during jaw (orthognathic) surgery better or worse. It aims to identify predictors that could improve safety and surgical conditions for patients undergoing bimaxillary osteotomy.
MoscowAges 18–40 - NCT05810428Enrolling by invitation
Using AI to predict outcomes and test pain treatment for trigeminal neuralgia
This study uses computer-based (AI) predictions to better understand what happens after a specific procedure for trigeminal neuralgia, a face pain condition. It also checks how well a “pain neuromodulation” approach works and what it feels like over time.
MilanAges 18 years+ - NCT05758467Enrolling by invitation
Study linking adult oral health, social factors, and heart health
This study looks at how people’s oral health in adulthood relates to social factors and heart health. To join, you must have already taken part in specific past health surveys.
BergenAges 71–72 - NCT05699343Enrolling by invitation
Gum surgery for implant inflammation using bone filler and a membrane
This study tests a gum surgery approach to treat peri-implantitis (infection/inflammation around a dental implant). It compares using a bone substitute alone versus adding a dissolvable collagen membrane to see which helps the implant area heal better.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05591326Enrolling by invitation
Injectable platelet-rich fibrin to close gum recession
This trial tests whether an injectable healing material called platelet-rich fibrin can help cover exposed tooth root in front teeth with gum recession. If it works, it may reduce tooth sensitivity and improve appearance for people with suitable, healthy teeth and gums.
KütahyaAges 18–65 - NCT05414019Enrolling by invitation
Braces study for tooth root damage in teens
This study compares different orthodontic force plans to see how they affect “root resorption,” when the tooth root shortens over time. It’s meant to find safer ways to move front lower teeth in teens who have a deep bite.
CairoAges 12–16 - NCT05397964Enrolling by invitation
Review of patients treated with direct pulp capping
This study looks back at dental treatment where calcium hydroxide was used to seal a tooth’s exposed pulp (the living inner part). It checks how well that approach worked and may help improve future treatment decisions.
IstanbulAges 18–50 - NCT05183503Enrolling by invitation
Study of pain, stress, anxiety, and depression in jaw disorder
This study looks at how chronic jaw pain from temporomandibular disorder (TMD) relates to stress, anxiety, and depression in adults. Your results may help researchers better understand what affects symptoms and how people respond to care.
WroclawAges 18–80 - NCT04847648Enrolling by invitation
Air polishing for gum infection around dental implants
This trial tests whether “air polishing” (a gentle cleaning method) can improve peri-implantitis, an infection and inflammation around dental implants. It may help by reducing deep gum pockets, bleeding, pus, and bone loss around the implant.
GothenburgAges 18 years+ - NCT04630587Enrolling by invitation
3D-printed fillings for back teeth needing repairs
This study tests how long different types of dental fillings made with 3D printing last in back teeth (premolars and molars). It may help you by comparing filling types in a careful, structured way.
OuluAges 18 years+ - NCT04266093Enrolling by invitation
Gene therapy follow-up for adults previously treated at NCI
This study is a follow-up check for people who were previously enrolled in certain NCI gene therapy treatment studies. It helps the research team monitor long-term effects and outcomes after treatment.
Bethesda, MarylandAges 18–120 - NCT03010150Recruiting
Blood tests and swallowing exercise check-ins for head and neck cancer
This study looks at whether giving swallowing exercises and checking in with questionnaires can help people with metastatic (spreading to neck lymph nodes) head and neck cancers do the exercises correctly. It also uses blood tests to better understand adherence and progress over time.
Houston, TexasAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Hormones & metabolism
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- Immune system & allergy
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- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.