Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07040397Recruiting
Massage therapy study for lower back pain
This study tests whether an electronic approach to massage therapy can help relieve lower back pain. It may be an option if you have persistent lower back pain and haven't used pain medications recently.
Rochester, MinnesotaAges 18 years+ - NCT07041736Recruiting
Laser combo for pain and infection after root canal
This trial tests if using ultrasound and a 980 nm diode laser together can reduce pain and kill bacteria better after a root canal. It may help if you have a tooth with an infection at the tip, but no symptoms.
CairoAges 20–35 - NCT07044323Recruiting
Virtual reality for phantom limb pain after leg amputation
This study tests whether using virtual reality at home for 30 minutes a day can reduce phantom limb pain after a leg amputation. It aims to improve how your brain handles pain signals.
Philadelphia, PennsylvaniaAges 18–100 - NCT07044713Recruiting
Fun activities for kids during blood tests
This trial tests if hand puppets, coloring books, or watching images can help children ages 3-6 feel less scared during blood draws. It's for healthy kids who need blood taken once.
Kilis, CentralAges 3–6 - NCT07044869Recruiting
Comparing two hand therapies for piriformis syndrome in women
This study compares two gentle hands-on treatments – a 'facilitated positional release' technique and a 'manual myofascial release' technique – to see which better relieves pain from piriformis syndrome in women.
IslamabadAges 25–50 - NCT07045974Recruiting
Stretching and mobilization for neck pain
This trial tests if a specific stretching and mobilization technique (Mulligan) reduces neck pain that travels down the arm. It may help if you have nerve-related neck pain confirmed by simple physical tests.
Peshawar, KPKAges 20–50 - NCT07047846Recruiting
Bowen technique vs. soft tissue therapy for frozen shoulder pain
This study compares two massage-like treatments (Bowen technique and dynamic soft tissue mobilization) to see which better reduces pain, improves movement, and helps daily function in people with frozen shoulder. It only includes diabetic patients with specific stages of frozen shoulder.
Lahore, Punjab ProvinceAges 50–80 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07048522Recruiting
Nimodipine before bowel cancer surgery
This trial tests if giving nimodipine before and after surgery for bowel cancer can help improve recovery and reduce pain. It may be a good fit if you meet the age and health requirements.
Pátrai, AchaeaAges 18–75 - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Cincinnati, OhioAges 18–85 - NCT07049029Recruiting
Physical activity and pain resilience study for teens
This study tests if physical activity can help teenagers with chronic pain feel better and be more active. It may help you learn ways to manage pain.
Columbus, OhioAges 12–17 - NCT07051772Recruiting
Predicting success in back pain rehab
This study looks for factors that help people with long-term low back pain succeed in rehabilitation programs. Researchers will track participants during their rehab to learn what works best.
Clermont-Ferrand, AuvergneAges 18–65 - NCT07052955Recruiting
Health riddles for less fear and pain in circumcised children
This study tests whether answering health riddles can help reduce fear, anxiety, and pain in children ages 4 to 6 getting circumcised. The goal is to make the experience less stressful for your child.
Gümüşhane, CenterAges 4–6 - NCT07053982Recruiting
New scan to find endometriosis spots
This trial tests a new type of PET/CT scan that uses a special tracer to find endometriosis lesions. It may help surgeons see exactly where the disease is, which could lead to more complete treatment.
ToulouseAges 18 years+ - NCT07054840Recruiting
Pain and walking learning in older adults
This study looks at how pain affects learning to walk on a special treadmill that moves each leg at a different speed. It's for healthy older adults who want to understand how pain might change the way they learn new walking patterns.
Newark, DelawareAges 55–90 - NCT07055178Recruiting
Virtual reality for pain and anxiety during vasectomy
This study tests if using a virtual reality headset during a vasectomy can help lower pain and anxiety. It compares VR with standard care to see which works better for patients.
Winnipeg, ManitobaAges 18 years+ - NCT07057128Recruiting
Do nerve issues occur in shoulder pain syndrome?
This study looks at whether nerve-related symptoms are common in people with subacromial pain syndrome (a type of shoulder pain). You may qualify if you have shoulder pain that has lasted at least 3 months, with moderate to severe pain in the past week, and if you haven't had shoulder surgery or certain other shoulder problems.
Izmir, İzmirAges 19 years+ - NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT07058220Recruiting
Neck training for neck pain relief
This trial tests whether special neck position-sense exercises can help people with general neck pain feel better. It may be a good option if you have neck pain without a specific injury.
GizaAges 25–45 - NCT07058636Recruiting
Nerve block plus trigger point shots for neck pain relief
This study tests if adding a nerve block to standard trigger point injections provides better relief for people with chronic neck pain caused by myofascial pain syndrome.
AnkaraAges 18–65 - NCT07058727Recruiting
Comparing agents for partial pulp treatment on tooth survival and pain
This trial tests different materials used to treat a small area of exposed tooth pulp after cavity removal in permanent teeth without pain or infection, to see which one helps the tooth survive and causes less pain afterward.
Adana, SarıçamAges 15–55 - NCT07059546Recruiting
Studying sensitivity to adrenomedullin in chronic post-traumatic headache
This trial tests whether people with long-term headache after a mild head injury have an abnormal reaction to a substance called adrenomedullin, which may play a role in causing headaches. You will receive adrenomedullin and a placebo in separate sessions to see how your headache responds.
Glostrup MunicipalityAges 18–65 - NCT07059754Recruiting
Cooling treatment for chronic eye surface pain
This trial tests a cooling treatment (EyeCool) for people with long-term pain on the eye's surface. It looks at how the treatment affects the eye's surface structure and inflammation after standard care hasn't worked well enough.
Melbourne, VictoriaAges 22–90
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.