Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT07719608Recruiting
MySalvia system for resistant migraine
This trial tests a device called MySalvia that is implanted in the head to reduce migraine attacks. It is for people whose migraines have not improved with at least three different preventive treatments.
Newnan, GeorgiaAges 22–84 - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT07716813Recruiting
Breast milk or sugar water for pain during heel prick in babies
This study tests whether giving breast milk or sugar water (10% or 20% dextrose) just before a routine heel prick can reduce pain and keep your baby's heart rate and oxygen levels more stable. It is designed for moderately premature babies in the NICU.
MersinAges 7 months–3.1 years - NCT07718217Recruiting
Mindfulness education for women with PCOS
This study tests whether a 4-week online mindfulness program can help women with PCOS manage stress and improve well-being. You'll attend group sessions and complete surveys from home.
BursaAges 18–49 - NCT07717021Enrolling by invitation
Patient feedback after umbilical hernia surgery
This study looks at how patients feel and function after surgery to fix a small, first-time umbilical hernia (a bulge near the belly button). Your feedback will help doctors understand what matters most to people like you.
Karlskrona, Blekinge CountyAges 18–75 - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT07718477Recruiting
Comparing child and parent pain during dental numbing
This study compares the pain a child feels during a numbing injection at the dentist to the pain the parent thinks the child is feeling. It helps doctors understand the difference between a child's actual pain and what parents perceive, which may improve how pain is managed during dental visits.
Clermont-FerrandAges 6–15 - NCT07716566Recruiting
Nerve block for pain after kidney transplant
This trial tests a nerve block called a quadroiliac plane block to see if it helps control pain after kidney transplant surgery. If you are having a kidney transplant, this study might help reduce your pain and need for pain medication.
Istanbul, IstanbulAges 18–80 - NCT07721571Recruiting
Numbing medicine around drainage tube for kidney stone surgery pain
This study tests whether injecting a local numbing medicine around the nephrostomy tube after kidney stone surgery can reduce pain after the procedure. If you are having this surgery, it may help you feel more comfortable during recovery.
Çorum, ÇorumAges 18–75 - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07720739Recruiting
Adding morphine to a spine block for belly surgery pain
This study tests whether adding a small dose of morphine to a numbing injection near the spine (called erector spinae plane block) provides better pain relief after midline belly surgery. It may help reduce the need for other pain medicines and improve recovery.
SohagAges 18–60 - NCT07717151Recruiting
Preventing long-term pain after surgery for chronic opioid users
This trial tests a method to prevent chronic pain after surgery in people who already take opioids regularly. It may help reduce long-term pain and improve recovery.
AmiensAges 18 years+ - NCT07716215Recruiting
Which exercise helps sacroiliac joint pain more?
This study compares two types of exercises—core stability exercises versus hip-strengthening exercises—to see which works better for reducing pain and improving function in people with long-term sacroiliac joint dysfunction. It may help you find a targeted treatment for your chronic pelvic or low back pain.
RawalpindiAges 25–55 - NCT07723001Recruiting
Mobilization for neck pain relief and function
This trial tests if moving the neck and upper back joints can reduce pain and improve daily life for people with nagging neck pain (lasting more than 4 weeks). It aims to find a simple hands-on treatment to help you feel better and move easier.
Lahore, Punjab ProvinceAges 20–40 - NCT07720336Recruiting
Essential oils and a wearable device for long-term nausea
This study tests whether a wearable device (like a wristband) and essential oils can help calm chronic nausea. It focuses on people who have had nausea for more than 6 months, feel it at least 3 times a week, and also have anxiety.
Columbus, OhioAges 18 years+ - NCT07723014Recruiting
Fascial vs muscle techniques for sacroiliac joint pain
This study compares two hands-on treatments for sacroiliac joint dysfunction, a common cause of lower back and hip pain. It aims to see which approach better reduces pain, improves movement, and helps with daily activities.
Lahore, Punjab ProvinceAges 30–45 - NCT07721389Recruiting
Breathing exercises vs. manual therapy for forward head posture
This study compares two non-drug treatments—special breathing exercises and hands-on manual therapy—to see which works better for fixing forward head posture and reducing neck pain in university students.
Istanbul, ZeytinburnuAges 18–28 - NCT07715292Enrolling by invitation
Muscle vibration during cycling exercise study
This trial tests whether applying gentle vibrations to your leg muscles during cycling can boost power and muscle activity. You will do a series of cycling tests while the vibration is on or off.
Wroclaw, Lower Silesian VoivodeshipAges 18–26 - NCT07723586Recruiting
TENS vs Ultrasound for mechanical neck pain
This trial compares two common treatments—TENS (a device that uses mild electrical pulses) and ultrasound therapy—along with neck exercises for long-lasting neck pain. You would get one of these treatments for several weeks to see which helps your pain more.
Karachi, SindhAges 18–45 - NCT07720817Recruiting
Ultrasound-guided nerve blocks for laparoscopic upper abdominal surgery
This study compares two types of nerve blocks (retrolaminar block and TAP block) to see which provides better pain relief after laparoscopic surgery on the upper belly. If you are having this type of surgery, you may be able to join.
Al Mansurah, Dakahlia GovernorateAges 21–65 - NCT06497140RecruitingPhase 3
Genicular artery embolization for painful knee osteoarthritis
This trial tests a new procedure called genicular artery embolization to treat knee pain from osteoarthritis. If you have moderate to severe knee pain and are not a candidate for knee replacement or other surgery, this treatment may help reduce pain and improve function.
ParisAges 40–90 - NCT06413914Recruiting
CBT for long-term pain in rheumatic disease
This trial tests if cognitive behavioral therapy (a type of talk therapy that helps change pain-related thoughts and behaviors) can reduce long-term pain in people with rheumatic diseases. It also validates a new questionnaire (AE-FS) about how pain affects daily life.
OsloAges 18 years+ - NCT06637709Recruiting
Pain after osteoarthritis treatment: a 24-month study
This study looks at why some people still have pain after knee surgery or other treatments for osteoarthritis. It tests a marker in the blood to see if it relates to ongoing pain. You would be followed for 24 months.
Roma, RomaAges 18–99
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.