Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06534853Recruiting
Stretching study for low back pain relief
This study compares two stretching techniques for a condition called quadratus lumborum syndrome, which causes low back or hip pain. Researchers want to see which type of muscle stretch works better to relieve pain and improve movement.
Rawalpindi, Punjab ProvinceAges 18–35 - NCT06204315RecruitingPhase 2
Spine radiosurgery for spinal cord compression
This trial tests a precise radiation technique for people whose spinal tumors are very close to the spinal cord or nerves. It aims to safely give higher radiation doses while limiting damage to the cord.
Houston, TexasAges 18 years+ - NCT06475391Recruiting
L-arginine supplement for exercise performance
This study tests whether taking L-arginine (a natural amino acid supplement) can improve your performance during short, intense exercise like sprinting or weightlifting. If you are a healthy, active adult, you may be able to join.
Winnipeg, ManitobaAges 18–39 - NCT06490484RecruitingPhase 2
A new capsule for diabetic nerve pain when pregabalin doesn't work
This trial tests an experimental drug (HSK16149) for people with long-term diabetic nerve pain that hasn't been helped enough by pregabalin. It aims to see if the new capsule can reduce pain more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT07447219Recruiting
Ergonomics program for dental workers
This study tests an ergonomics program designed to reduce muscle and bone pain in dental healthcare workers. If you are a practicing dental professional, this program may help you prevent work-related injuries.
Serdang, SelangorAges 25–65 - NCT06275087Recruiting
Recovery speed after anesthesia for mouth surgery
This trial compares how quickly people recover from anesthesia after mouth surgery. It may help if you are having a soft-tissue procedure inside your mouth that takes 30 minutes to 2 hours.
ZagrebAges 18 years+ - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT06536803Recruiting
Strength training with or without stretching for plantar fasciitis
This study tests whether adding specific stretches for the plantar fascia to high-load strength training helps male athletes with plantar fasciitis feel better. It compares strength training alone to strength training plus targeted stretching.
Mirpur MatheloAges 20–35 - NCT06520306Enrolling by invitation
Ropivacaine with methylene blue for hip surgery pain
This trial tests if adding different amounts of methylene blue to a standard numbing medicine (ropivacaine) can improve pain relief, thinking ability, and hip movement after hip replacement surgery.
TaizhouAges 60–85 - NCT07440199Recruiting
Comparing two pain blocks for lung surgery without a breathing tube
This study compares two different pain-blocking techniques for a specific type of lung surgery. It aims to see which one provides better pain relief for patients who are awake during the procedure.
ElâzığAges 18–65 - NCT07655349Recruiting
Comparing two ways to attach gum grafts after surgery
This study tests if using small titanium tacks to hold a gum graft in place causes less pain than the usual stitches. It might help people who need more attached gum around their teeth.
Cairo, Cairo GovernorateAges 18 years+ - NCT06347679Recruiting
Can aromatherapy ease anxiety and pain during dental work?
This study tests whether smelling certain essential oils (aromatherapy) can help reduce anxiety and pain during dental treatments. If you are an adult having a dental procedure, this may be a way to feel more comfortable without medication.
Chengdu, SichuanAges 18–40 - NCT07426965Recruiting
Ultrasound findings and pain in stroke patients with shoulder pain
This study uses ultrasound to look at the shoulder on the side affected by stroke and see how it relates to pain. It may help understand why shoulder pain happens after a stroke.
AnkaraAges 18–75 - NCT06384001Recruiting
Meditation for chronic low back pain in older adults
This trial tests whether a meditation program can help reduce chronic low back pain in adults aged 50 and older. You'll learn meditation techniques that you can do at home using an internet connection, and the study will track how your pain changes over time.
Tallahassee, FloridaAges 50–89 - NCT05711394RecruitingPhase 3
Atogepant for preventing episodic migraine in children
This study tests whether an oral medicine called atogepant can reduce migraine activity in children ages 6–17 and checks its side effects. It’s meant for kids with episodic migraine (not the more constant types) who may benefit from preventive treatment.
Huntsville, AlabamaAges 6–17 - NCT07655921Recruiting
Enhanced recovery after knee replacement surgery
This trial tests a special care plan called ERAS to help people recover faster after total knee replacement. It compares this plan to standard care to see if it reduces hospital stay and improves recovery.
Karachi, SindhAges 50–70 - NCT07170267Recruiting
Pain relief study for cesarean section
This study tests whether a nerve block in the lower belly wall (transversalis fascia plane block) or a medication injected into the spinal fluid (intrathecal dexmedetomidine) provides better pain relief for mothers having a planned cesarean section under spinal anesthesia.
Tanta, El-GharbiaAges 18–40 - NCT06630819Recruiting
Comparing different volumes of numbing medicine for tooth removal
This study tests whether using a smaller amount of a numbing medicine (articaine) works as well as the usual amount for numbing the area before removing a lower back tooth. It aims to make the procedure more comfortable and efficient.
Buraidah, Al QassimAges 18 years+ - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT07650396RecruitingPhase 3
Steroid Injections for Long-Term Achilles Tendon Pain
This study tests whether steroid injections can help people with chronic Achilles tendon pain (the tendon at the back of your heel) who haven't improved with physical therapy and exercise. The injection is designed to reduce inflammation and pain in the middle part of the tendon.
RotterdamAges 18–65 - NCT07155837Enrolling by invitation
TENS for pain after first knee replacement surgery
This study tests if a TENS device, which uses mild electrical pulses to relieve pain, helps people recover better after their first total knee replacement. It might reduce pain and improve movement.
Adana, AdanaAges 18 years+ - NCT06426706Recruiting
Nerve Blocks for Pain After VATS Lung Surgery
This study compares two types of nerve blocks (TPVB and SPSIPB) to see which is better at controlling pain after keyhole lung surgery. If you are having VATS, the trial may help you have less pain and recover more comfortably.
IstanbulAges 18–80 - NCT06837298Recruiting
Fava bean extract supplement for muscle recovery
This trial tests whether a supplement made from fava bean protein can help your muscles recover strength after exercise. You would take the supplement for about 2 weeks and have your muscle function tested before and after.
Bradenton, FloridaAges 18–45 - NCT06376981RecruitingPhase 3
Hyaluronic acid injection for shoulder tendon pain
This trial tests if an injection of hyaluronic acid (a natural lubricant) can reduce pain and improve function in people with shoulder tendinopathy (irritation of a tendon). It’s for those who haven’t gotten better with other treatments like rest or physical therapy.
La Roche-sur-YonAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.