Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07630350Enrolling by invitation
Virtual Reality for Young People With Chronic Pain
This study tests whether wearing virtual reality goggles can help young people (ages 7–21) manage chronic pain in their neck, shoulders, or arms. Researchers want to see if VR activities can reduce pain and improve daily life.
Allison Park, PennsylvaniaAges 7–21 - NCT07629323Enrolling by invitation
Spinal Pain Relief During Hiatal Hernia Surgery
This trial tests whether injecting pain medication directly into the spinal fluid during a minimally invasive stomach surgery (called fundoplication) helps reduce pain after the operation. Fundoplication is used to treat severe acid reflux.
Karlstad, Värmland CountyAges 18 years+ - NCT07308587Recruiting
Nerve pain after chest tube for broken ribs
This study looks at nerve pain that can happen after a chest tube is placed to treat broken ribs from an injury. The goal is to understand how common it is and how it affects recovery, so doctors can better support patients.
Toronto, OntarioAges 18 years+ - NCT06409689Recruiting
Oliceridine for pain relief after upper abdominal surgery
This study tests a new pain medicine called oliceridine after laparoscopic upper abdominal surgery. It aims to improve pain control and recovery compared to standard opioids.
Wuhan, HubeiAges 18–70 - NCT06430814Recruiting
Blood test to predict nerve damage from paclitaxel
This study looks at whether certain markers in your blood can predict nerve damage from paclitaxel chemotherapy. If you join, researchers will monitor your nerve health during treatment to better understand and possibly prevent side effects.
OdenseAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06237647Recruiting
Comparing injections for partial rotator cuff tears
This study compares three types of injections—steroids, PRP (platelet-rich plasma), and PRP combined with hyaluronic acid—to see which works best for partial rotator cuff tears. If you have shoulder pain from a partial tear, this trial may help find the most effective treatment for you.
Kaohsiung City, SanminAges 20–85 - NCT07139522Recruiting
Dexamethasone or magnesium for pain relief after C-section
This trial tests adding dexamethasone or magnesium sulfate to the numbing medicine given as a back injection (erector spinae plane block) to see if it provides better pain relief after a planned C-section. The goal is to reduce pain and the need for extra painkillers after surgery.
CairoAges 18–35 - NCT06744816RecruitingEarly Phase 1
Can capsaicin cream ease nerve pain after chemotherapy?
This study tests whether a capsaicin cream (made from chili peppers) can help reduce pain in the legs caused by nerve damage from past chemotherapy. It's for people who still have pain 3 months or more after finishing chemo.
Houston, TexasAges 18 years+ - NCT06406010RecruitingPhase 4
Nerve block for pain after hip surgery
This trial tests whether a specific nerve block can reduce pain after a hip socket surgery. The results could help improve recovery and reduce the need for strong painkillers.
CopenhagenAges 18 years+ - NCT06731348Enrolling by invitationPhase 4
Pain pill options after pelvic surgery
This trial compares two different amounts of opioid pain pills after surgery for women with pelvic floor problems. The goal is to see if a lower dose still provides good pain relief and keeps patients satisfied.
Bethesda, MarylandAges 18 years+ - NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07033104Recruiting
Adding calcitonin to numbing medicine for C-section pain relief
This study tests if adding a medication called calcitonin to the usual numbing medicine (bupivacaine) can provide better pain relief after a cesarean section. It is for women who are having a planned C-section under spinal anesthesia.
Tanta, Gharbia GovernorateAges Any age - NCT07614555Recruiting
Breathing methods during back surgery recovery
This study compares two ways doctors control your breathing during lumbar disc herniation (slipped disc) surgery. Researchers want to see which method keeps your lungs healthier during the operation.
AnkaraAges 18–65 - NCT07061067Recruiting
How symptom duration affects lower back surgery results
This study looks at how long your symptoms have lasted before lower back surgery and whether that affects your recovery. If you're planning a lumbar spine operation and have symptoms like back or leg pain, this trial may help doctors understand the best timing for surgery.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT07606781Recruiting
Nerve Blocks for Pain Relief During Hysterectomy Surgery
This study tests two types of nerve-blocking injections given during abdominal hysterectomy (removal of the uterus) to reduce pain and opioid use after surgery. The goal is to help you recover more comfortably with fewer strong pain medications.
Tanta, El-GharbiaAges 18 years+ - NCT06317233Enrolling by invitation
Team-based program for chronic pelvic pain in women
This research study tests a team-based program for women with ongoing pelvic pain. The goal is to see if a coordinated approach with different specialists can help manage pain and improve quality of life.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06098586Recruiting
Nerve surgery vs exercise for wrist arthritis
This study compares two treatments for wrist arthritis: a surgery that cuts certain wrist nerves to stop pain signals, versus structured hand exercises. It may help if you have chronic wrist pain from a specific type of arthritis and haven't had previous wrist nerve surgery.
MalmöAges 18 years+ - NCT06377969Recruiting
Spinal cord stimulation for chronic pelvic pain
This study tests a device called a spinal cord stimulator — a small implant that sends mild electrical pulses to nerves in your spine — to see if it can reduce long-term pelvic pain that hasn't gotten better with other treatments.
Redwood City, CaliforniaAges 18 years+ - NCT07629505Recruiting
CoQ10 supplement for chronic pelvic pain in men
This trial tests whether a CoQ10 supplement (Ralivia) can reduce chronic pelvic or perineal pain lasting at least 3 months. The study aims to see if this supplement helps relieve symptoms when other treatments haven't fully worked.
ThessalonikiAges 18–50 - NCT07417436Recruiting
Graded motor imagery for foot or ankle osteoarthritis
This study tests a technique called graded motor imagery to see if it can reduce pain and improve movement in people with foot or ankle osteoarthritis. The treatment involves specific mental exercises, so it might help if you have chronic ankle pain.
Antalya, AntalyaAges 18 years+ - NCT03231150Recruiting
Study for heel pain from plantar fasciitis
This trial studies treatments for ongoing heel pain caused by plantar fasciitis (pain in the band on the bottom of your foot). If you qualify, you may receive an injection treatment and be compared with a control group to see what works best.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06288282Recruiting
Predicting pain and opioid misuse in chronic back pain
This study looks at how thinking and behavior affect long-term pain and opioid use in people with chronic lower back pain. It aims to find better ways to manage pain and prevent medication misuse.
New York, New YorkAges 18 years+ - NCT07627854Recruiting
Cold therapy after knee replacement surgery
This study compares two ways to reduce pain and swelling after total knee replacement: a special cold wrap (cryocuff) versus a standard ice pack. You'll help researchers understand which method works better for your recovery.
Kremmen, BrandenburgAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.