Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07485387Recruiting
Korean cognitive aging study using smartphone app
This study looks at how thinking and memory change as people get older. It uses a smartphone app to track these changes over time in healthy older adults living in South Korea.
Seoul, Select One...Ages 60 years+ - NCT07486505Recruiting
Mindfulness for pain after arm or leg fracture surgery
This study tests whether brief mindfulness sessions before and after surgery help people manage pain and anxiety while recovering from a broken arm or leg, and may reduce the need for strong painkillers (opioids). It aims to see if this approach is practical and helpful for patients.
Hamilton, OntarioAges 18 years+ - NCT07489014Enrolling by invitation
Therapy techniques for neck pain relief
This trial tests two hands-on treatments—gentle joint movement and soft tissue release—to see which better helps long-lasting neck pain. It could offer pain relief without surgery or strong medications.
IstanbulAges 18–65 - NCT07481864Recruiting
Early mental exercise after shoulder tendon repair
This study tests if a gentle, early mental exercise program helps improve shoulder recovery after a specific type of rotator cuff repair. It might be a good fit if you had surgery on two front shoulder tendons and are otherwise healthy.
Istanbul, TurkeyAges 30–65 - NCT07482709RecruitingPhase 1/Phase 2
Nerve block with or without ketamine for hysterectomy pain
This study compares two ways to reduce pain after a hysterectomy: a standard nerve block with bupivacaine (a numbing medicine) versus the same block plus ketamine (a medicine that can boost pain relief). The goal is to see if adding ketamine provides better comfort after surgery.
Karachi, SindhAges 25–65 - NCT07483216Recruiting
Exercise study for women with fibromyalgia
This trial tests a special type of strength exercise (isokinetic exercise) to see if it can help women with fibromyalgia feel better and move easier. It may be a good fit if you are generally stable on your current treatments and able to exercise safely.
Valladolid, ValladolidAges 18 years+ - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07486232Enrolling by invitation
Neck pain relief with posture exercises and taping
This study tests whether combining postural exercises with taping can help people with long-term neck pain who work at a desk. It aims to find a simple way to reduce pain and improve comfort.
IstanbulAges 25–55 - NCT07484698Recruiting
Myofascial release with FIFA 11+ for hamstring health
This study tests whether adding a gentle muscle release technique to a proven warm-up program (FIFA 11+) can improve hamstring flexibility and lower your risk of injury. It's for male football players who can commit to a 6-week program.
Chakdara, KPKAges 16–30 - NCT07484815Recruiting
Virtual reality for pain during egg freezing
This study tests whether using a virtual reality (VR) headset during egg freezing can help reduce pain. If you are having your eggs retrieved to preserve your fertility, you may be able to take part and wear a VR device to see if it makes the procedure more comfortable.
JerusalemAges 18–45 - NCT07488832Recruiting
Intravenous lidocaine infusion for lumbar fusion surgery
This study tests whether giving lidocaine through an IV during and after lumbar fusion surgery can help reduce pain and improve recovery. Lidocaine is a numbing medicine that may decrease pain and the need for other pain drugs.
AnkaraAges 18 years+ - NCT07486349Recruiting
Comparing two numbing blocks for shoulder surgery
This study compares two types of numbing blocks used during shoulder surgery to see which one works better and safer. It may help you because the block can provide pain relief after surgery.
IstanbulAges 18–75 - NCT07487987Recruiting
Imagery and exercises for chronic neck pain
This trial tests whether imagining movements (motor imagery) and doing special neck exercises can help people with long-term neck pain. You may be eligible if your neck pain has lasted at least 3 months and is at least moderate, and you haven't had recent neck surgery or therapy.
Konya, KaratayAges 18–65 - NCT07483190Recruiting
Nerve block for pain after laparoscopic hysterectomy
This study tests a nerve block called M-TAPA to reduce pain after laparoscopic hysterectomy. It may help you need less pain medicine and recover more comfortably.
IstanbulAges 18–70 - NCT07482371Recruiting
Scooping vs. cupping for stiff elbows in kids
This study compares two gentle therapies—scooping mobilization and dynamic cupping—to see which better helps children regain elbow movement after a fracture. It may be an option for kids who have had their elbow in a cast or splint for at least 3 weeks.
Lahore, Punjab ProvinceAges 6–13 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06775535Recruiting
Spinal cord stimulation trial for chronic pain
This trial tests a closed-loop spinal cord stimulator that adjusts stimulation based on nerve signals. It may help people with chronic pain who are already scheduled to try this type of device.
RoeselareAges 18 years+ - NCT06778460Recruiting
Esketamine and lidocaine for pain after liver surgery
This trial tests whether two medicines, esketamine and lidocaine, can reduce long-term pain after liver surgery and possibly improve survival. It is for people who are having a planned liver removal (hepatectomy).
Chengdu, SichuanAges 18–75 - NCT06777771Recruiting
Reformer Pilates for first-time pregnant women
This trial tests if Reformer Pilates (a type of exercise using a special machine) helps first-time pregnant women stay healthy. If you are in your first pregnancy and between 11 and 22 weeks along, this may be a good fit for you.
Izmir, KonakAges 18–35 - NCT06779396RecruitingPhase 4
Scalp injection to reduce pain after brain surgery in children
This trial tests if injecting a mix of two medicines (triamcinolone and ropivacaine) into the scalp before brain surgery can lower pain in children afterward. It compares this to standard care to see if it helps kids recover more comfortably.
Beijing, Beijing MunicipalityAges 2–12 - NCT06075004Recruiting
Hip pain relief study comparing two injection methods
This trial tests two ways to give pain medicine around the hip joint during surgery to see which provides better pain relief. It may help patients experience less pain after hip replacement.
Santiago, Santiago MetropolitanAges 18–80 - NCT06322407Recruiting
Ultrasound-guided neck injection for treating chronic migraine
This study tests whether a nerve block injection near the neck (called stellate ganglion block), guided by ultrasound, can reduce chronic migraine pain. It may be a good option if you have chronic migraine and haven't found relief from standard preventive medications.
Beijing, Beijing MunicipalityAges 18–65 - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65 - NCT07477860RecruitingPhase 1
Achilles tendon pain treatment trial
This trial tests a minimally invasive treatment for chronic Achilles tendon pain that hasn't improved with at least 3 months of rest, therapy, or other non-surgical care. It aims to help people who want to avoid surgery.
Libertyville, IllinoisAges 25–80
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.