Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07543614Recruiting
Frame Running for Kids and Teens With Movement Challenges
This study looks at whether Frame Running—a special bike activity—helps children and teens with cerebral palsy or other movement disabilities stay active and involved in their communities. Researchers want to see if regular Frame Running training improves participation and exercise for young people.
Odense, Region SyddanmarkAges 8–18 - NCT07327905Recruiting
Lidocaine or dexmedetomidine for pain during weight-loss surgery
This trial compares two medicines given through an IV during sleeve gastrectomy (weight-loss surgery) to see which provides better pain control. It may help patients have a smoother recovery with less discomfort.
AlexandriaAges 20–50 - NCT06834685Recruiting
Laser therapy for nerve pain after chemotherapy
This study tests a special laser treatment (photobiomodulation) to reduce nerve pain caused by chemotherapy in cancer patients. If you have had nerve pain for at least 3 months after chemo and can attend twice-weekly sessions, this may help ease your pain.
Mougins, Alpes MaritimesAges 18 years+ - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07723001Recruiting
Mobilization for neck pain relief and function
This trial tests if moving the neck and upper back joints can reduce pain and improve daily life for people with nagging neck pain (lasting more than 4 weeks). It aims to find a simple hands-on treatment to help you feel better and move easier.
Lahore, Punjab ProvinceAges 20–40 - NCT07723014Recruiting
Fascial vs muscle techniques for sacroiliac joint pain
This study compares two hands-on treatments for sacroiliac joint dysfunction, a common cause of lower back and hip pain. It aims to see which approach better reduces pain, improves movement, and helps with daily activities.
Lahore, Punjab ProvinceAges 30–45 - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT07723586Recruiting
TENS vs Ultrasound for mechanical neck pain
This trial compares two common treatments—TENS (a device that uses mild electrical pulses) and ultrasound therapy—along with neck exercises for long-lasting neck pain. You would get one of these treatments for several weeks to see which helps your pain more.
Karachi, SindhAges 18–45 - NCT07248475Recruiting
Battle rope training for elbow pain and stiffness after injury
This study tests whether battle rope exercises can help children ages 8–15 with elbow stiffness and pain after an injury. It aims to improve movement and reduce discomfort.
Lahore, Punjab ProvinceAges 8–15 - NCT07324343Recruiting
Education for shoulder pain: which patients benefit most?
This study tests whether patients with different types of shoulder pain respond better to learning about their condition through education alone. You will receive information and advice to help you manage your pain without injections or surgery.
IstanbulAges 18–65 - NCT07325994Recruiting
Pain control during hysteroscopy for women with infertility
This trial tests if using calming words (verbal analgesia) during a hysteroscopy can reduce pain compared to standard care. It is for women with primary infertility who need this procedure to check the uterus.
GizaAges 18–40 - NCT07726251Recruiting
Heart changes during jaw surgery
This study looks at how your heart and blood pressure change during a type of jaw surgery called bimaxillary orthognathic surgery. It will help doctors understand a reflex that can affect your heart rate during the procedure.
Kirikkale, KırıkkaleAges 18–40 - NCT07726797Recruiting
Pelvic control training vs core stability for low back pain
This trial compares two types of exercises — pelvic control training with a pressure sensor versus core stability training — to see which one works better for relieving low back pain. It may help if you are a young adult with no other health issues affecting your back or balance.
Lahore, Punjab ProvinceAges 18–30 - NCT06124664Recruiting
Study of leg vein drainage in pelvic varicose veins
This study looks at how blood flows from the legs in people with varicose veins in the pelvis. It may help doctors understand the link between pelvic and leg vein problems.
MoskvaAges 18–40 - NCT06471725Recruiting
Pilates for sports hernia recovery
This study tests whether adding Pilates exercises to standard hernia rehab helps people with sports hernia recover faster. You would do Pilates sessions along with your usual rehab.
Al Mansurah, Dakahlia GovernorateAges 18–45 - NCT07337772Recruiting
Comparing corticosteroid doses in knee replacement pain relief injection
This study compares different doses of a corticosteroid (an anti-inflammatory medicine) injected into the knee during total knee replacement surgery. The goal is to see which dose provides the best pain relief after surgery. It is for people having their first knee replacement due to osteoarthritis.
Fuzhou, FujianAges 18–100 - NCT07028034Recruiting
Six-minute step test for chronic back pain
This trial uses a simple step test to measure how chronic low back pain affects your daily function. It may help doctors better understand your condition without needing expensive equipment.
KırşehirAges 18–65 - NCT06642649Recruiting
Comparing anesthesia types to reduce opioids in hysterectomy
This study compares general anesthesia alone to two types of combined anesthesia (general plus spinal) to see which reduces the amount of opioid painkillers needed during and after a laparoscopic hysterectomy. It may help patients recover with less reliance on strong pain medications.
Bellinzona, SwitzerlandAges 18 years+ - NCT07031791Recruiting
Picturing daily tasks to assess arm use after injury
This study uses pictures to evaluate how often you use your arm for everyday tasks and whether you avoid using it, which can help understand recovery after a suspected brachial plexus or similar nerve injury.
AngersAges 18 years+ - NCT07331129Recruiting
Nerve block for pain relief in groin lymph node surgery
This trial tests a special ultrasound-guided nerve block to reduce pain during and after groin lymph node removal. It may help patients undergoing this type of cancer surgery have less pain and use fewer painkillers.
CairoAges 18–65 - NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT07237867Recruiting
Nerve stimulation for knee pain in athletes
This study tests if a mild electrical current to a nerve in the groin area can improve thigh muscle strength in athletes with long-standing jumper's knee (patellar tendinopathy). The goal is to see if this treatment can help reduce pain and improve function.
Barcelona, BarcelonaAges 18–40 - NCT06288256Recruiting
Spine surgery study: genes, thinking, and pain
This study is for people getting planned spine surgery. It looks at how your genes and thinking skills might affect your pain and use of pain medicine after surgery.
New York, New YorkAges 18 years+ - NCT06108375Recruiting
Live vs recorded music therapy for palliative care patients
This trial compares live music therapy to a recorded version for people in palliative care. It aims to see which format is more acceptable and comforting for patients with advanced illness.
Zurich, Canton of ZurichAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.