Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06594796Recruiting
Lifestyle program for back pain and weight
This trial tests a combined exercise and lifestyle program for people with long-lasting low back pain who are overweight or have obesity. The program is delivered by physical therapists and aims to improve physical function and reduce pain.
AmsterdamAges 18 years+ - NCT07464860Recruiting
Breathwork for older adults after knee surgery
This study tests a breathing exercise program to help older adults recover after knee replacement surgery. Participants practice controlled breathing at home using a smartphone or computer.
Tucson, ArizonaAges 65 years+ - NCT07466446Recruiting
Tracking movement after ICU to support recovery
This study uses a small device (accelerometer) to track your movement after leaving the ICU. It aims to see if monitoring physical activity can help improve recovery for patients at higher risk of setbacks.
EdinburghAges 18 years+ - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT07467499Recruiting
How leisure activities affect quality of life in low back pain
This study looks at how your hobbies and free-time activities might improve your quality of life if you have long-term low back pain (pain that lasts 12 weeks or more). You will answer questionnaires about your daily life and what you enjoy doing.
BrusselsAges 18 years+ - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07471269Recruiting
Online pain education for fear of childbirth
This trial tests an online education program about pain neuroscience to help pregnant women reduce fear of childbirth. It may be useful if you are in your third trimester and want to feel more prepared.
Alfara del Patriarca, ValenciaAges 18–50 - NCT07464093Recruiting
Pilates for joint hypermobility pain
This trial tests if a special Pilates program can reduce pain in people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder. You must have had pain for at least 3 months and be able to get on and off the floor on your own.
Chestnut Hill, MassachusettsAges 18 years+ - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT07463430Enrolling by invitationPhase 4
Suzetrigine for pain after non-mastectomy breast surgery
This trial tests a new pain medication, suzetrigine, for people having breast surgery (not mastectomy) who are expected to have moderate pain. It checks if this drug works well compared to standard options.
San Diego, CaliforniaAges 18 years+ - NCT07470307Recruiting
Exercise for chronic low back pain: Pilates vs. strength training
This trial compares dynamic lumbar strengthening exercises to Pilates, both combined with myofascial release, for people with ongoing low back pain. It aims to find which approach works better for reducing pain and improving function.
Lahore, Punjab ProvinceAges 25–35 - NCT07468734Recruiting
Shock wave vs. physical therapy for knee arthritis
This study compares two treatments for chronic knee osteoarthritis: shock wave therapy and traditional physical therapy. The goal is to see which one helps reduce pain and improve function better.
CairoAges 40 years+ - NCT07470021Recruiting
Numbing injection for pain relief after ankle surgery
This study tests whether a numbing injection around the ankle nerves before surgery can reduce pain and help you recover faster after ankle arthroscopy. It is for people having this keyhole surgery and staying in the hospital for a short time.
Hangzhou, ZhejiangAges 18–65 - NCT07465887Recruiting
Comparing two nerve blocks for pain relief after lung surgery
This study compares two different pain-blocking injections given before lung surgery to see which one works better. It may help reduce pain and make recovery more comfortable.
ThessalonikiAges 18–85 - NCT07463170Recruiting
French translation of a pain assessment tool for newborns
This study is translating a pain assessment tool for newborns into French and testing it with healthcare workers in neonatal units. It aims to improve pain recognition in babies who cannot speak.
Paris, Île-de-France RegionAges Any age - NCT07465991Recruiting
Online insomnia therapy for fibromyalgia and activity
This study tests if an online therapy program for insomnia (using cognitive behavioral therapy, or CBT) can help people with fibromyalgia sleep better and be more physically active. If you have fibromyalgia and trouble sleeping, this treatment may improve your pain and daily function.
OxfordAges 18 years+ - NCT07467070Recruiting
Pilates for posture, core strength, and flexibility in young adults with low back pain
This study tests whether a 6-week Pilates program can improve posture, core strength, and flexibility in young adults with mild to moderate low back pain that has no clear cause. It could help you learn exercises to ease your pain and strengthen your back.
Lahore, Punjab ProvinceAges 18–25 - NCT07468097Recruiting
How metabolism affects pain in women with lipedema
This study looks at how metabolic health (like blood sugar and thyroid function) may influence pain and sensitivity in women with lipedema. It aims to better understand these links to improve treatment approaches.
Istanbul, PendikAges 18 years+ - NCT06104384Recruiting
Chronic pain patients with injury claims study
This study looks at injury claims from people with chronic pain to better understand their experiences. It may help improve care for others with similar conditions.
Surrey, British ColumbiaAges 20–99 - NCT05618002Recruiting
Study compares sleep medicines for chronic pain insomnia
This trial tests different treatments to help people with long-term (chronic) pain and severe insomnia sleep better. It’s looking at three options—one medicine (lemborexant) compared with existing sleep medicines (zopiclone and clonidine)—and whether they improve sleep when non-medicine sleep strategies haven’t worked.
Surrey, British ColumbiaAges 20–99 - NCT05945719Recruiting
Study on harassment discrimination against pain staff
This study focuses on adult people living with chronic pain. It may be looking at how patient behavior and workplace discrimination or harassment affect pain care staff.
Surrey, British ColumbiaAges 20–99 - NCT05938101Recruiting
Pain clinic study on adult chronic pain
This study focuses on adult people with ongoing (chronic) pain. It’s looking at experiences with pain clinic staff during the time around COVID.
Surrey, British ColumbiaAges 20–99 - NCT06076512Recruiting
Pain clinic safety trial for adults with chronic pain
This trial is testing whether a pain clinic can improve public health safety for adults who have chronic pain and also face social or emotional challenges. It aims to see if this kind of care helps people feel better and avoids opioid-related harms.
Surrey, British ColumbiaAges 20–99
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.