Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07426367Recruiting
Online therapy for chronic pain and emotional distress
This trial tests an online therapy program that uses acceptance and commitment therapy (ACT) to help people with chronic pain who also feel anxious or depressed. The goal is to improve emotional well-being and daily functioning.
LundAges 18–65 - NCT07434427RecruitingPhase 4
Buprenorphine vs. oxycodone for pain after lung surgery
This study compares two common pain medicines given through a patient-controlled pump after lung surgery done with small incisions. The goal is to see which one works better and has fewer side effects.
Zabrze, Silesian VoivodeshipAges 18–75 - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07429916RecruitingEarly Phase 1
Ketamine for shoulder pain after weight loss surgery
This trial tests if a single dose of ketamine, given during surgery, can reduce common shoulder pain after laparoscopic gastric sleeve surgery. If you are having this weight-loss procedure and meet the weight and health criteria, this study may help improve your recovery.
IrbidAges 18–60 - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+ - NCT06813495Recruiting
ACT for injury prevention in nurses and aides
This study tests a program called Acceptance and Commitment Therapy (ACT) to help nurses and nursing aides prevent injuries at work. If you work in a long-term care facility in specific areas of the US or Thailand, you may be able to join.
Bowling Green, OhioAges 18 years+ - NCT06813937Recruiting
Magnetic stimulation for feeling in upper limb amputation
This study tests whether magnetic stimulation can improve sensation in people who have lost an upper limb. It may help restore feeling in the residual limb.
MoscowAges 18–65 - NCT05412615Recruiting
Meniscal graft surgery for wrist arthritis
This trial studies whether using a donor meniscus (meniscal allograft) during wrist replacement surgery can help people with painful wrist osteoarthritis. It’s mainly for certain types of arthritis changes in the wrist (SLAC or SNAC) and specific age ranges.
Englewood, ColoradoAges 30–80 - NCT06811077Recruiting
Health coaching by a patient expert for chronic pain
This trial tests whether one-on-one coaching sessions led by a trained patient expert can help people better manage chronic pain. If you already attend a chronic pain clinic and are open to learning new coping skills, this program may support you.
Paris, FranceAges 18 years+ - NCT07421245Enrolling by invitation
Testing a new stemless shoulder implant for osteoarthritis
This study tests a new stemless shoulder replacement system for people with shoulder arthritis. The implant uses a metal anchor without a stem and a plastic socket that may be cemented or press-fit.
Florham Park, New JerseyAges 20 years+ - NCT06816082Recruiting
Online therapy for chronic pain rehabilitation
This trial tests if adding internet-based acceptance therapy to standard pain rehabilitation helps adults with chronic pain. It is for patients at the Linköping pain clinic who have internet access.
Linköping, Östergötland CountyAges 18 years+ - NCT06816056Recruiting
Foot therapy for hemophilia ankle arthritis
This study tests if manual therapy can help patients with hemophilia who have arthritis in their ankle. It seeks to improve joint health and reduce pain.
MurciaAges 18–65 - NCT07424638Recruiting
Nerve blocks for shoulder pain after lung surgery
This trial compares two types of nerve blocks to prevent shoulder pain after lung cancer surgery. If you are having open-lung surgery for lung cancer, you may be able to join.
CairoAges 18–65 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07424209Recruiting
Hypnotic communication during heart catheterization study
This study tests whether talking in a special relaxed way (hypnotic communication) during a heart procedure can help you feel calmer and more comfortable. You may be able to join if you are at least 18, can understand Italian, and are already scheduled for a coronary angiogram.
Ponderano, ItalyAges 18 years+ - NCT07425457Recruiting
Cold nerve treatment before knee replacement surgery
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
AthensAges 18 years+ - NCT07418944Recruiting
Surgery vs. non-surgery for leg pain from a slipped disc
This trial compares surgery to non-surgical treatments for people with leg pain caused by a lumbar disc herniation (slipped disc). It tests if surgery provides better relief after at least 6 weeks of symptoms.
HelsinkiAges 18–60 - NCT07423039Recruiting
Ear acupressure for anxiety and pain during breast cancer surgery
This study tests if pressing on specific points on the ear (acupressure) can help reduce anxiety and pain during breast cancer surgery. It compares acupressure plus standard care to standard care alone, and may be a drug-free way to help you feel calmer before and after your procedure.
StuttgartAges 18–99 - NCT07418632Recruiting
Motion training for neck pain using smart classification
This study tests a special motion-training program for people with neck pain. It uses a computer to classify and guide your movements, which may help reduce pain better than usual care.
LjubljanaAges 18–65 - NCT07423910Recruiting
Numbing injections for better recovery after hernia surgery
This study looks at two types of numbing injections (TAP and RS blocks) to see which helps people recover better after groin hernia surgery. If you are having a planned single-side hernia repair, you might qualify to join.
TampereAges 18 years+ - NCT07417462Recruiting
Pain relief after heart surgery to help you recover faster
This trial tests a combination of pain medicines given during cardiac surgery to reduce pain and speed up recovery. It may help patients who are having a first-time bypass surgery through a standard breastbone incision.
AsyutAges 40–60 - NCT07420192Recruiting
A study on nerve surgery for pain after leg amputation
This trial tests a surgery called RPNI to treat painful nerve growths (neuromas) in people who have lost a leg. The goal is to reduce severe pain and improve the ability to use a prosthetic limb.
Ankara, AnkaraAges 18–70 - NCT06804564Recruiting
Cold vs warm water for muscle pain recovery
This trial compares cold water and warm water immersion to see which helps recover from muscle soreness after exercise. If you are a healthy young man with moderate muscle pain from working out, this study may help you recover faster.
Biała Podlaska, Lublin VoivodeshipAges 18–25
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.