Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07435207Enrolling by invitation
Blood clot risk study in CRPS patients
This study looks at factors that might increase the risk of blood clots in people with CRPS (Complex Regional Pain Syndrome). It aims to help doctors better understand and manage these risks.
Pavia, PaviaAges 18 years+ - NCT07440199Recruiting
Comparing two pain blocks for lung surgery without a breathing tube
This study compares two different pain-blocking techniques for a specific type of lung surgery. It aims to see which one provides better pain relief for patients who are awake during the procedure.
ElâzığAges 18–65 - NCT07442435Recruiting
Reiki for recovery after knee replacement surgery
This study tests whether adding Reiki (a gentle hands-on relaxation therapy) to standard care helps people feel better and recover more comfortably after a first-time knee replacement. It may be a good fit if you are having your first knee replacement, are not on certain medications, and haven't tried energy therapies before.
SinopAges 18 years+ - NCT07440069RecruitingPhase 4
Pain relief options for women during active labor
This trial compares the pain relief and effects of tramadol, paracetamol (also known as acetaminophen), and a placebo in women during active labor. It aims to find which option works best and is safest for mothers and babies.
Tegucigalpa, Francisco Morazán DepartmentAges 15–45 - NCT07438522Recruiting
Hand strength exercises for female badminton players
This trial tests two types of hand strengthening exercises (isometric and isotonic) in female competitive badminton players. It aims to see which approach better improves hand and grip performance, which can help with racquet control and power.
Lahore, Punjab ProvinceAges 18–30 - NCT07440940Recruiting
Timing of pain blocks for gallbladder surgery recovery
This study is testing whether giving a numbing block (under the ribs and around the belly button) at a certain time before gallbladder removal surgery helps reduce pain after the operation. It aims to find the best timing for these pain blocks to improve your recovery.
SeoulAges 18–80 - NCT05806021RecruitingPhase 4
Tested different cortisone doses for knee osteoarthritis pain
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
Montreal, QuebecAges 50 years+ - NCT05840354Recruiting
Brain stimulation plus steroid shots for chronic spinal pain
This trial studies whether adding rTMS (a non-invasive brain stimulation treatment) to steroid joint injections can better reduce chronic spinal pain. It’s designed for people who already need repeated steroid joint injections to manage pain.
London, OntarioAges 18 years+ - NCT06808295RecruitingPhase 1
Dexmedetomidine for tear duct surgery
This study tests whether a medication called dexmedetomidine can reduce the amount of anesthesia needed during tear duct surgery (DCR), possibly making the procedure safer and more comfortable.
GizaAges 16–75 - NCT06715085RecruitingPhase 4
PRGF injections for chronic low back pain
This trial tests whether injections of a blood-based treatment called PRGF can help people with long-term low back pain caused by worn discs. It is for those who haven't gotten relief from standard treatments like medication.
Vitoria-Gasteiz, AlavaAges 18 years+ - NCT07426965Recruiting
Ultrasound findings and pain in stroke patients with shoulder pain
This study uses ultrasound to look at the shoulder on the side affected by stroke and see how it relates to pain. It may help understand why shoulder pain happens after a stroke.
AnkaraAges 18–75 - NCT05193227RecruitingPhase 2
Slow-release lidocaine patch for pain after pelvic surgery
This Phase 2 study tests a slow-release form of lidocaine to reduce pain after surgery that uses a pelvic incision. If you’re having a qualifying pelvic operation, the study may help see whether this medication improves postoperative pain control.
Vancouver, British ColumbiaAges 19 years+ - NCT05831345RecruitingPhase 3
Methadone during surgery to prevent post-surgery pain
This Phase 3 trial tests whether giving methadone during hip or knee replacement surgery can reduce pain after surgery. It may help some people use less rescue pain medicine afterward, but it also has safety checks for kidney, liver, heart, and opioid-related risks.
BrusselsAges 18–80 - NCT07432425Recruiting
Exercise programs for chronic neck pain
This study compares different exercise programs to see which one improves physical and mental health in people with chronic neck pain. You may be eligible if you have had neck pain for at least 3 months and it is moderate to severe, but you haven't been in a recent neck pain rehab or exercise program.
Ankara, AltindagAges 20–65 - NCT07426367Recruiting
Online therapy for chronic pain and emotional distress
This trial tests an online therapy program that uses acceptance and commitment therapy (ACT) to help people with chronic pain who also feel anxious or depressed. The goal is to improve emotional well-being and daily functioning.
LundAges 18–65 - NCT07430228Enrolling by invitationPhase 2
Can oxytocin help you recover faster after hip replacement?
This study tests if a medicine called oxytocin, given through a vein during surgery, can help people recover more quickly after a total hip replacement. It is for adults in generally good health who are scheduled for a first-time hip replacement.
Winston-Salem, North CarolinaAges 18–75 - NCT07433686Recruiting
Saskatoon Berry Juice for Muscle Recovery
This trial tests whether Saskatoon berry juice helps muscles recover after exercise. It involves healthy adults aged 18–35 who can exercise safely.
Saskatoon, SaskatchewanAges 18–35 - NCT07431632Recruiting
Nerve freezing vs. epidural for pain after pectus excavatum repair
This study compares two ways to manage pain after pectus excavatum surgery: freezing the nerves during surgery (cryoanalgesia) versus an epidural block. The goal is to see which method provides better pain relief with fewer side effects.
São Paulo, São PauloAges 13 years+ - NCT07432841Recruiting
Personalized brain stimulation for chronic pain
This trial tests a personalized form of brain stimulation (high-definition tDCS) to treat chronic pain that has not improved with other treatments. If you have had pain for at least 6 months and it is still moderate to severe, this may be an option to explore.
MilanAges 18–75 - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07429669Recruiting
Comparing shoulder nerve blocks for pain and breathing
This study compares two different shoulder nerve blocks to see which one provides better pain relief after shoulder surgery while also checking how they affect your breathing. If you are having a shoulder arthroscopy, you may be eligible to help find the safest and most effective pain control option.
Yenimahalle, AnkaraAges 18–65 - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07428070Recruiting
Exercise program for rotator cuff shoulder pain
This trial tests if a specially designed exercise program can reduce shoulder pain related to the rotator cuff. It may help if you've had shoulder pain for more than three months.
IstanbulAges 18–75 - NCT07434427RecruitingPhase 4
Buprenorphine vs. oxycodone for pain after lung surgery
This study compares two common pain medicines given through a patient-controlled pump after lung surgery done with small incisions. The goal is to see which one works better and has fewer side effects.
Zabrze, Silesian VoivodeshipAges 18–75
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.