Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06820073Recruiting
Stretching study for office workers with neck or back pain
This study tests if a gentle stretching method using a special hammock can help reduce neck and back discomfort for people who sit at work. It's looking for volunteers who have some aches but no serious diagnoses.
Zaragoza, ZaragozaAges 18–65 - NCT05263297Recruiting
Testing two ways to reduce anxiety during blood draws
This study compares two combined programs to help children feel less stressed during a blood draw. It uses simple, child-friendly activities to see which approach works better for coping during the procedure.
KaramanAges 8–10 - NCT06776887Recruiting
Virtual reality exercises for burn recovery on legs
This trial tests whether virtual reality exercises can help people with leg burns improve balance and reduce depression and anxiety. It is for people who had a large thermal burn on their lower body at least 3 months ago.
GizaAges 35–55 - NCT07412522Recruiting
Pain relief injection for minimally invasive heart bypass surgery
This study tests whether a special injection between the ribs can reduce pain after minimally invasive heart bypass surgery. The injection is given before surgery to help with pain control and may reduce the need for strong pain medicines.
IstanbulAges 18–75 - NCT07411521Recruiting
Comparing two pain relief methods after planned cesarean
This trial compares two ways to manage pain after a planned cesarean section: one combines a spinal and epidural injection, the other is a newer type of nerve block. The goal is to see which provides better pain relief with fewer side effects.
Bursa, NilüferAges 18–45 - NCT07413055RecruitingPhase 3
Comparing two doses of dexamethasone for dental implant pain
This study tests whether a higher dose of dexamethasone (8 mg) works better than a lower dose (4 mg) for reducing pain after getting a single dental implant. It may help find the best way to manage discomfort after surgery.
MuscatAges 21–80 - NCT06784089Recruiting
Hip fracture type, nutrition and pain after surgery
This study looks at how a person's nutrition before hip surgery relates to their pain levels after surgery. It aims to help doctors improve recovery for older adults.
AnkaraAges 65 years+ - NCT07412223RecruitingPhase 4
Tegileridine for bowel recovery after abdominal surgery
This trial tests a painkiller called Tegileridine to see if it helps your bowels work normally again after abdominal surgery.
Guangzhou, GuangdongAges 18 years+ - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT07413107Recruiting
Italian version of a back pain disability questionnaire
This study is testing a new Italian questionnaire that measures how much low back pain affects your daily life. It's for people who have had low back pain for at least 3 months and speak Italian.
Lissone, MilanoAges 18–90 - NCT07411352Recruiting
Side-lying vs. Back-lying during labor for first-time mothers
This study compares lying on your side versus lying on your back during active labor to see if one position helps speed up labor. It is for first-time mothers with a healthy, full-term pregnancy and a baby in the head-down position, who have not yet had their water break.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45 - NCT07411859Recruiting
Reboot Pain: Brain stimulation for chronic pain
This trial uses a gentle brain stimulation technique called tDCS to see if it can reduce chronic pain in people with certain pain conditions. You would self-administer the treatment and report your results.
Atlanta, GeorgiaAges 18–89 - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT07409012Recruiting
Pain assessment tool for cesarean delivery patients
This study is developing a new questionnaire to better measure pain after cesarean section. If you had a planned or unplanned cesarean with spinal or epidural anesthesia in the last 2-3 days and speak German or Swiss German, you may help improve how pain is assessed for future mothers.
Basel, Canton of Basel-CityAges 18 years+ - NCT07409688RecruitingPhase 4
Pain relief after gallbladder surgery: comparing two ways to give local anesthetic
This trial compares two methods of giving local anesthetic during laparoscopic gallbladder removal to see which provides better pain relief. It may help patients recover with less pain after surgery.
Rawalpindi, Punjab ProvinceAges 15–60 - NCT07408193RecruitingEarly Phase 1
Lidocaine and ketamine for severe cancer pain not helped by opioids
This trial tests if adding lidocaine and ketamine to your current pain medicines can better control severe cancer-related pain that opioids alone haven't helped.
Athens, AtticaAges 18 years+ - NCT07409337Recruiting
Self-acupressure for period pain and PMS
This trial tests if doing acupressure on yourself can reduce period pain and premenstrual symptoms over about six months. It might help if you have painful periods and are looking for a non-medicine option.
Niğde, MerkezAges 18–30 - NCT07410780Recruiting
Pain after root canal with two different sealers
This trial compares two types of root canal filling materials—bioceramic and calcium hydroxide—to see which one causes less pain after the procedure. If you have a tooth with a live but inflamed nerve, you may be able to join.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT07410793RecruitingPhase 2
Acupuncture plus herbal cream vs standard cream for plaque psoriasis
This trial tests if adding a Chinese herbal cream to acupuncture works as well as adding a standard psoriasis cream (calcipotriol) to acupuncture. It's for people with mild to moderate plaque psoriasis and may offer a natural treatment option.
Muang, ChiangraiAges 18–65 - NCT07414017Recruiting
Virtual reality exercise for older adults with low back pain
This study tests if using virtual reality during exercise helps older adults with long-term low back pain. You'll do exercises while focusing your attention in different ways, and researchers will see which method works best for reducing pain and improving movement.
Center, Kirşehi̇rAges 65–80 - NCT07411417Recruiting
Acupressure for pain and lung function after chest surgery
This trial tests if acupressure can help reduce pain and improve lung function after a first-time chest surgery. It may offer a non-drug way to support recovery.
IstanbulAges Any age - NCT07409753RecruitingPhase 2
How oxytocin affects nerve signals in healthy women
This study tests how a single dose of oxytocin affects nerve signals in your arm. It helps researchers understand how oxytocin might change the way your body senses touch or pain.
LinköpingAges 18–65 - NCT07415967Recruiting
Dual-task exercise for rotator cuff shoulder pain
This study tests an exercise program that combines shoulder movements with mental tasks (like counting or naming things) to improve pain and function. It is for people with ongoing shoulder pain from common rotator cuff problems.
IstanbulAges 18–65 - NCT06817135Recruiting
Shoulder exercises for breastfeeding neck pain
This trial tests if special shoulder-blade (scapular) exercises can help reduce neck pain in mothers who are exclusively breastfeeding. The exercises are simple and designed to strengthen the muscles that support your neck while you hold your baby.
Giza, DokkiAges 18–35
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.