Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06652724Recruiting
Psychological help for chronic pain in fibromyalgia and migraine
This study looks at how psychological factors and treatments might help with chronic pain in people with fibromyalgia and/or chronic migraine. It compares different groups to understand what works best.
Rome, RMAges 18–50 - NCT06653634RecruitingPhase 4
Optimizing treatment for kids with JIA in remission
This trial tests whether children with juvenile idiopathic arthritis (JIA) who have been doing well for over a year can safely reduce their medications. The goal is to find the best way to keep arthritis under control while avoiding unnecessary treatments.
BergenAges 2–17 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT06653985Recruiting
Hip injection plus physical therapy for mild hip problems
This trial tests a combination of a steroid and lubricant injection into the hip joint plus physical therapy to treat mild hip arthritis or related issues like a labral tear. It aims to see if this approach can reduce pain and improve function without surgery.
Hamilton, OntarioAges 40–60 - NCT06653998Recruiting
Early movement and rehab in ICU patients
This study tests whether starting physical therapy and movement early is safe and possible for patients in the intensive care unit. It aims to improve recovery for people who are stable enough to participate.
Bogotá, Bogota D.C.Ages 18 years+ - NCT06654349Recruiting
Recovery after thumb surgery: a diary study
This study compares how quickly people recover after two types of thumb surgery for arthritis. You will keep a diary and do some simple check-ups to track your recovery.
Zoetermeer, South HollandAges 18 years+ - NCT06655701Recruiting
Bladder leaks and muscle loss in postmenopausal women with bone thinning
This study looks at whether women with osteoporosis (thin bones) after menopause also have bladder leaks and loss of muscle mass. It may help understand links between these conditions.
IstanbulAges 50–75 - NCT06658249Recruiting
Core exercises vs foot-ankle strength for knee arthritis
This study compares core strengthening exercises with foot-ankle exercises to see which helps more with knee osteoarthritis symptoms like pain and walking difficulty. It might help you move better and climb stairs more easily.
Lahore, Punjab ProvinceAges 40–65 - NCT06658327Recruiting
Stretching for knee arthritis in postmenopausal women
This study compares two types of stretching to see which better reduces pain and improves movement in postmenopausal women with knee osteoarthritis. It may help you find a simple, drug-free way to manage your symptoms.
Lahore, Punjab ProvinceAges 50–65 - NCT06659991RecruitingEarly Phase 1
Pain and daily tasks in jaw joint disorder
This study tests how pain from a jaw joint disorder (TMD) affects your ability to do daily tasks. You'll track your pain and activities on your smartphone to help researchers understand the link.
Minneapolis, MinnesotaAges 21–65 - NCT06661681Recruiting
Cognitive functional therapy for chronic shoulder pain
This study tests a new type of therapy called Cognitive Functional Therapy (CFT) for people with ongoing shoulder pain. It focuses on how you move and think about your pain, and aims to help you manage better without surgery or injections.
João Pessoa, ParaíbaAges 18–60 - NCT06663384Recruiting
Arvis vs conventional knee replacement study
This trial compares a new ARVIS surgical system to standard knee replacement. It's for adults needing a first-time total knee replacement due to severe osteoarthritis.
Tampa, FloridaAges 18 years+ - NCT06664359Recruiting
Safer trigger point injections using ultrasound guidance
This study is testing a safer way to give trigger point injections — shots that relieve painful muscle knots — in the upper back. Researchers will use ultrasound to guide the needle and measure how close it is to the lungs, to avoid complications.
AnkaraAges 18–65 - NCT06665204Recruiting
Knee pain treatment study for active military
This study tests whether following a standard treatment guide helps active-duty service members with kneecap pain feel better. You would receive physical therapy and be monitored for a few weeks.
San Diego, CaliforniaAges 18 years+ - NCT06665607Recruiting
Foot muscle training for people with MS
This study tests whether training the small muscles in your feet can improve your walking and balance if you have multiple sclerosis (MS). It is for people with moderate disability, so you can still walk but may have some trouble.
ValladolidAges 18–70 - NCT06666023Recruiting
A paper test to diagnose orthopedic infections
This trial tests a new paper-based device to quickly diagnose infections after joint replacement or spine surgery. It may help avoid delays from standard lab tests.
Rome, LazioAges 18 years+ - NCT06666608Recruiting
Bone stimulator for back stress fractures
This trial tests whether a bone stimulator device can help heal a specific type of spinal stress fracture (spondylolysis) in people aged 16 to 40 who are active in sports and plan to do physical therapy.
Houston, TexasAges 16–40 - NCT06666595Recruiting
Short vs standard implant for lower partial denture
This trial tests whether a shorter dental implant placed slightly below the bone works as well as a standard-length implant placed at the bone level to hold a lower removable partial denture more securely. It may help you if you have a loose denture and enough bone for one of these implants.
Al MansurahAges 50–70 - NCT06666816Recruiting
Watching changes in walking for muscle and nerve diseases
This study watches how people with certain muscle or nerve diseases walk over time. It may help doctors understand changes in walking patterns and is open to adults who can walk and have a genetic diagnosis of a neuromuscular condition.
Bosisio Parini, LeccoAges 18–75 - NCT06668181RecruitingPhase 3
Study of bimekizumab for kids with certain types of juvenile arthritis
This trial tests a drug called bimekizumab in children and teens with specific types of juvenile arthritis (enthesitis-related arthritis or psoriatic arthritis). It aims to see how the drug works in the body and if it's safe. This may help those who haven't gotten enough relief from standard anti-inflammatory medicines.
CalgaryAges 2–18 - NCT06668415Recruiting
Spencer technique after hydrodilation for frozen shoulder
This trial tests if adding a gentle hands-on treatment (Spencer technique) to the standard fluid injection procedure (hydrodilation) helps people with frozen shoulder move more easily and feel better. If you have been diagnosed with unilateral frozen shoulder and have already had the hydrodilation procedure, you may qualify.
Rawalpindi, Punjab ProvinceAges 40–65 - NCT06669000Recruiting
How long to dissolve gout crystals
This study looks at how long it takes for urate crystals (the cause of gout) to dissolve in the body. It may help if you have gout, are not on uric acid-lowering medicine, and have higher uric acid levels.
ParisAges 18 years+ - NCT06669013RecruitingPhase 3
Chemo-immunotherapy for young people with bone or soft tissue sarcoma
This trial tests whether adding immunotherapy (a treatment that helps your immune system fight cancer) to chemotherapy can help young people whose bone or soft tissue sarcoma has come back or hasn't responded to previous treatment.
Saint PetersburgAges Up to 18 years
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.