Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07442383Recruiting
Exercise and ergonomics program for teachers with pain
This study tests whether an exercise and ergonomics training program can help teachers with long-term muscle or joint pain feel better. You would learn simple exercises and better ways to move at work to reduce discomfort.
Bitlis, TatvanAges 30–60 - NCT06971757Recruiting
Is yearly check-up after hip or knee replacement needed?
This study looks at whether routine check-ups one year after hip or knee replacement are helpful or unnecessary. If you've had or are scheduled for a first hip or knee replacement for arthritis, you may be able to join.
AmsterdamAges 50 years+ - NCT07440849Recruiting
Core stability and pelvic exercises for sacroiliac joint pain
This study tests whether core stability and pelvic clock exercises can reduce pain in women with sacroiliac joint dysfunction after childbirth. It may help you if you are a new mom with significant lower back or pelvic pain.
Sargodha, Punjab ProvinceAges 25–35 - NCT07440615Recruiting
Leg muscle and heart performance in active adults
This study looks at how leg muscle size relates to heart and muscle performance in healthy men and women. It aims to understand normal differences between sexes.
EskişehirAges 18–30 - NCT07438522Recruiting
Hand strength exercises for female badminton players
This trial tests two types of hand strengthening exercises (isometric and isotonic) in female competitive badminton players. It aims to see which approach better improves hand and grip performance, which can help with racquet control and power.
Lahore, Punjab ProvinceAges 18–30 - NCT05992883RecruitingPhase 3
Comparing two injections for thumb arthritis pain
This study tests whether an NSAID injection or a corticosteroid injection works better for thumb base arthritis. If you have ongoing pain despite using things like ibuprofen, ice, or a brace, this trial may help find which treatment offers better relief.
Rochester, MinnesotaAges 40 years+ - NCT07436143Recruiting
Posture and quality of life in Duchenne muscular dystrophy
This study looks at how different body positions affect daily life and well-being in children with Duchenne muscular dystrophy. It may help find ways to improve comfort and function.
Lahore, Punjab ProvinceAges 5–9 - NCT06951035Recruiting
Brain stimulation and BCI for arm movement after stroke
This study tests whether combining brain stimulation (rTMS) with a brain-computer interface (a device that reads your brain signals) can help improve arm and hand movement after a stroke. It is for people who had a single stroke more than 6 months ago and still have some weakness but can move their fingers slightly.
ParisAges 18–85 - NCT05883995Recruiting
Phage therapy clinic program in Lyon
This trial is an organized clinic to help patients request bacteriophage (phage) therapy. It mainly checks that you were referred to the Lyon hospital for a phage therapy request and that you agree to be part of the program.
LyonAges Any age - NCT07407036Recruiting
Virtual reality rehab for wrist instability
This study tests whether adding virtual reality exercises to standard physical therapy helps people with a specific wrist ligament injury. It compares usual rehab with a program that uses fun, virtual-reality games to improve strength and control.
IstanbulAges 18–65 - NCT06953258Enrolling by invitation
Lengthening muscle exercises for older adults' function
This study tests whether a special type of exercise (eccentric training, which focuses on lengthening your muscles) can improve your ability to move and balance. It is designed for healthy older adults who are not already doing strength training.
NantesAges 60–80 - NCT07424703Recruiting
Bright Light Therapy for Teen Scoliosis
This study tests whether using a special bright light device at certain times of day can help improve spine curvature in teenagers with scoliosis. It is for adolescents who are night owls and have mild to moderate scoliosis.
Zhejiang, ZhejiangAges 10–15 - NCT06585566Recruiting
Bone graft trial for children with cleft palate
This trial tests a new way to repair a gap in the upper jawbone (called an alveolar cleft) using thin layers of bone, called cortical shells, taken from the patient's own body. It is for children who have not had this surgery before and who are generally healthy.
CairoAges 8–15 - NCT06892678RecruitingPhase 1/Phase 2
DFMO maintenance for relapsed Ewing sarcoma or osteosarcoma
This trial tests a drug called DFMO given as maintenance therapy to keep cancer from coming back. It is for people under 40 who have finished treatment for relapsed Ewing sarcoma or osteosarcoma and currently show no signs of cancer.
The Bronx, New YorkAges Up to 39 years - NCT05132348Recruiting
Studying immune markers in people with osteoporosis
This study looks at immune system “fingerprints” (immunophenotyping) in adults who have been diagnosed with osteoporosis. It may help researchers understand what drives osteoporosis and could guide better future treatments.
Bonn, Northrhine WestfaliaAges 18 years+ - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT07411625Recruiting
Pre-surgery exercise program for ACL injury patients
This trial tests whether doing special exercises before ACL surgery (called prehabilitation) helps you recover better after the operation. It's for people who have a first-time ACL tear and are scheduled for reconstruction surgery using a tendon from their own body.
NantesAges 18 years+ - NCT07404046Recruiting
Comparing tendon grafts for ACL surgery
This trial compares two types of grafts using the semitendinosus tendon for ACL reconstruction. It aims to see if adding a part of the tendon's muscle improves healing and stability after surgery.
ZagrebAges 18–50 - NCT07412821Enrolling by invitationPhase 1
Study of ASA-001 for ADSS1 deficiency muscle disease
This trial tests a drug called ASA-001 (adenylosuccinic acid) for people with a rare genetic muscle disease caused by ADSS1 deficiency. The goal is to see if it is safe and helps muscle function.
Los Angeles, CaliforniaAges 18 years+ - NCT06581887Recruiting
Measuring behavior and emotions in Duchenne and Becker muscular dystrophy
This study looks at how to measure behavioral and emotional challenges in boys with Duchenne or Becker muscular dystrophy, and in boys without the condition. It aims to find better ways to assess these issues, which could help improve care and treatments.
LondonAges 7–17 - NCT06354543Recruiting
A study on Teknimed bone cement for joint replacement
This study is looking at how well Teknimed bone cements and cement restrictors work for people who need a joint replacement (like a hip or knee). If you are scheduled for a joint replacement or have already had one using these products since 2016, you may be able to join.
Brive-la-Gaillarde, AquitaineAges 18 years+ - NCT06939244Recruiting
Krill oil for muscle recovery after exercise in older adults
This trial tests whether taking krill oil helps people 60 and older recover faster from muscle-straining exercise. If you do light resistance exercise less than 1 hour per week and have no major health issues, you may qualify.
Glasgow, OtherAges 60 years+ - NCT07406893Recruiting
Reducing Infection Risk in Shoulder Replacement Surgery
This trial tests whether a special gel (Prontosan) applied during shoulder replacement surgery can reduce the risk of infection. It is for men having their first shoulder replacement.
St Louis, MissouriAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.