Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07564167Recruiting
Dextrose Injection for Tailbone Pain Relief
This study tests whether injecting dextrose (a sugar solution) under ultrasound guidance can relieve chronic tailbone pain that hasn't improved with standard treatments like physical therapy or medication. The injection is designed to stimulate healing in the painful area.
IstanbulAges 18–75 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06732700Recruiting
Initial neck exercises for forward head posture and pain
This study tests if initial neck exercises can improve how well you sense your neck's position (proprioception) and reduce pain in people with forward head posture and chronic neck pain.
Islamabad, FederalAges 18–40 - NCT07567092Recruiting
VIRTUGUIDE System for Bunion Foot Surgery
This study tests a new computer-guided system to help surgeons perform bunion correction surgery (called a Lapidus procedure) more accurately. Participants will receive this guided surgery along with a standard implant, and researchers will track how well the surgery works and how patients recover.
Virginia Beach, VirginiaAges 22 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT07568015Recruiting
Nerve-targeted treatment for lateral hip pain
This study tests an experimental treatment that targets nerves around the hip to relieve pain on the outside of the hip. It may help people who have tried other treatments without enough relief.
Sun City, ArizonaAges 22–80 - NCT07564154RecruitingPhase 1
Testing KT502 injections for active rheumatoid arthritis
This is an early-stage study testing a new injectable treatment called KT502 for people with moderate-to-severe rheumatoid arthritis (RA) that hasn't responded well to standard treatments. The study will check if the medication is safe and how the body responds to it.
Bayswater, VictoriaAges 18–75 - NCT07561203Recruiting
Collavant supplement for runner's knee discomfort
This study tests whether Collavant®, a collagen-based supplement, reduces knee pain in amateur runners aged 40–65 who experience discomfort during or after training. You'll take the supplement for 24 weeks while continuing to run and track your symptoms.
Madrid, MadridAges 40–65 - NCT06732765Recruiting
Eloda with or without muscle energy for back pain relief
This trial tests whether adding a muscle relaxation technique to Eloda treatment helps people with lower back pain caused by a tight muscle near the hip. It aims to find a more effective way to reduce pain and improve movement.
Sialkot, Punjab ProvinceAges 18–45 - NCT05168124Recruiting
Therapy or short breaks for chronic fatigue syndrome (CFS/ME)
This study tests whether Acceptance and Commitment Therapy (ACT) or doing brief “micro breaks” can improve symptoms in people with CFS/ME. It checks safety and whether you can follow the online program over the study period.
ZurichAges 18–55 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT07566936Enrolling by invitation
Digital vs. Traditional Splints for Jaw Joint Disorders
This study compares two types of custom-made jaw splints—one designed using digital technology and one made the traditional way—to see which better relieves jaw pain and improves mouth opening in people with temporomandibular disorder (TMD), a common condition affecting the jaw joint.
Islamabad, IslamabadAges 18–40 - NCT07566832Recruiting
Strength Training and Inflammation in Older Adults
This study tests whether a specific type of strength training reduces inflammation in the body for adults aged 60–75. Researchers will measure how your body responds to this training over time.
TaipeiAges 60–75 - NCT07563842Enrolling by invitation
Defining Abdominal Pressure Complications After Surgery
This study is updating medical definitions for a serious condition called abdominal compartment syndrome—where pressure builds up in the belly after surgery or critical illness. The research involves expert doctors and patients who have experienced this condition, working together to clarify what it is and how to recognize it.
LublinAges 18 years+ - NCT07559890Recruiting
Nerve ablation for low back pain with Modic changes
This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.
PragueAges 18 years+ - NCT07561697Recruiting
Achilles Tendon Surgery Options for Clubfoot in Young Children
This study compares two surgical approaches to lengthen the Achilles tendon (the cord at the back of the heel) in young children with clubfoot—a condition where the foot is twisted inward and downward. The goal is to find which method works better and causes fewer complications.
Karachi, SindhAges 2–5 - NCT07565272Enrolling by invitation
Virtual Reality Game for Duchenne Muscular Dystrophy Arm Strength
This study tests a video game played in virtual reality to see if it helps people with Duchenne muscular dystrophy (a muscle-weakening condition) use their arms and hands better. Researchers want to understand if the game is easy to use and enjoyable.
IstanbulAges 7 years+ - NCT07562425Recruiting
Knee Strengthening Exercises for Patellofemoral Pain
This study compares three types of thigh muscle exercises to help reduce knee pain in people with patellofemoral pain syndrome (pain around the kneecap). Researchers want to see which exercise style—holding steady, moving through motion, or lowering slowly—works best for your pain.
Elâzığ, MErkezAges 18–50 - NCT07564427Recruiting
Electromagnetic therapy to reduce pain after hip replacement
This study tests whether a special electromagnetic therapy, added to standard recovery exercises, can reduce pain and improve movement after hip replacement surgery. The therapy is non-invasive and may help you regain function faster.
TaipeiAges 18–99 - NCT07567807Recruiting
Understanding Tests for Chronic Heel Pain
This study evaluates the best ways to diagnose and measure chronic heel pain (plantar fasciitis) in patients considering surgery. By comparing patients with long-lasting heel pain to those without foot problems, researchers aim to improve how doctors identify and assess this condition.
Bologna, BOAges 18–18 - NCT07568340Recruiting
Supervised versus home exercises for shoulder impingement
This trial compares two ways to treat subacromial impingement syndrome (a common shoulder condition causing pain with overhead movements): supervised rehabilitation sessions versus exercises you do at home. The goal is to see which approach works better for reducing pain and improving shoulder function.
Kırşehir, KırşehirAges 30–65 - NCT07564713Recruiting
Shock Wave vs. Laser Therapy for Tennis Elbow
This study compares two non-surgical treatments for tennis elbow (lateral epicondylitis): extracorporeal shock wave therapy and low-level laser therapy. Both treatments aim to reduce pain and improve function in people with chronic elbow pain caused by overuse.
ÇorumAges 18–65 - NCT07561255Recruiting
Testing a digital health app for everyday use and satisfaction
This study evaluates how well patients accept and use Axia, a digital health app designed for specific health conditions. Researchers want to understand if a 14-day trial period helps patients decide whether the app is right for them.
Würzburg, BavariaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.