Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07568340Recruiting
Supervised versus home exercises for shoulder impingement
This trial compares two ways to treat subacromial impingement syndrome (a common shoulder condition causing pain with overhead movements): supervised rehabilitation sessions versus exercises you do at home. The goal is to see which approach works better for reducing pain and improving shoulder function.
Kırşehir, KırşehirAges 30–65 - NCT06407063Recruiting
Long-term results after surgery for lumbar spinal stenosis
This study looks at patients who had back surgery for lumbar spinal stenosis and a condition called spondylolisthesis between 2007 and 2015. They want to see how many people needed another operation years later.
TromsøAges 18 years+ - NCT06736756Recruiting
Stretching hip muscle to help with knee pain
This trial tests if stretching the tensor fascia lata muscle (near your hip) changes how the muscle on the inside of your kneecap works. It is for people who have front knee pain without a specific injury, especially when doing things like running, squatting, or climbing stairs.
CairoAges 18–30 - NCT04713774Recruiting
Tracking bone and blood vessel changes after kidney transplant
This study follows people who recently received a kidney transplant to see how bone strength and blood-vessel calcifications change over time. It may help doctors better understand what to monitor after transplant and how best to protect bone and heart health.
LiègeAges 18 years+ - NCT07551856Recruiting
Robotic vs. manual knee replacement surgery for arthritis
This study compares two ways to perform knee replacement surgery for osteoarthritis: traditional manual surgery versus robotic-assisted surgery. Both are standard approaches; the trial tests whether robotic guidance improves how well your knee works after surgery.
Glasgow, ScotlandAges 18 years+ - NCT07553611Recruiting
Regional anesthesia and shoulder surgery recovery outcomes
This study compares different numbing techniques used during shoulder arthroscopy (a minimally invasive shoulder surgery) to see which one helps patients recover better, use less pain medication, and experience fewer complications like temporary paralysis of the breathing muscle under the rib cage.
Antalya, MuratpaşaAges 18–65 - NCT07554092Recruiting
Fast vs. Standard Casting for Baby Club Foot Treatment
This study compares two ways of treating club foot (a condition where a baby's foot is twisted inward at birth) using casts: a faster method and the traditional method. It will measure which approach works better using X-rays to see how well the foot straightens.
Peshawar, KPKAges 1 day–5 months - NCT07555899Recruiting
Bone marrow scaffold for ankle cartilage damage repair
This study tests whether a scaffold (a support structure) filled with cells from your bone marrow can help heal deep ankle joint damage when combined with a surgical technique called retrograde drilling. The goal is to regenerate damaged bone and cartilage in the ankle.
BolognaAges 18–55 - NCT07552415Recruiting
Joint Immobilization After Knee Replacement Revision Surgery
This study tests whether keeping your knee still for a period after revision knee replacement surgery helps improve how well you can bend and straighten it. Researchers want to see if immobilization (using a brace or cast) helps you regain better movement compared to standard care.
New York, New YorkAges 18 years+ - NCT07555496Recruiting
Back Pain Treatment After Spine Surgery: Injection vs. Needling
This study compares two ways to treat long-lasting back pain in people who have had spine surgery: injections into the back muscles versus dry needling (inserting thin needles into tight muscles). Both are combined with physical therapy to see which helps reduce pain better.
St-MaloAges 18 years+ - NCT07559539Recruiting
Life after scoliosis surgery: long-term outcomes study
This research follows adults who had spine-straightening surgery (called fusion) for adolescent scoliosis in their teens. Researchers want to understand how surgery affects your daily life, physical function, and quality of life 10–25 years later.
Warsaw, Masovian VoivodeshipAges 25–40 - NCT07556042Recruiting
Machine Learning to Predict Scoliosis Progression in Teens
This study uses artificial intelligence to predict how adolescent scoliosis (curvature of the spine) might progress over time. By understanding which teens are most at risk, doctors hope to catch and treat the condition earlier.
IstanbulAges 10–18 - NCT07555691Recruiting
Chinese herbal medicine for fibromyalgia pain relief
This trial tests whether a traditional Chinese herbal medicine called Yishen Shujin Decoction can reduce fibromyalgia pain. Fibromyalgia is a condition causing widespread body pain and fatigue; this study aims to see if this herbal treatment helps relieve those symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07556874Recruiting
Study of Surgeries for Multiple Bone Tumors
This research looks at surgery records from patients who had multiple osteochondromas (benign bone tumors) treated at a major orthopedic hospital. The study aims to understand what surgical approaches work best for this condition.
Bologna, BolognaAges Any age - NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT07553273Recruiting
Vibration to reduce pain from steroid hand and arm injections
This study tests whether applying gentle vibration during steroid injections into the hands, wrists, or elbows can reduce injection pain. If vibration works, it could make these commonly prescribed treatments more comfortable for patients.
Galveston, TexasAges 18 years+ - NCT07553221Recruiting
Treatment study for complex ankle fractures with cartilage damage
This research studies how to treat severe ankle fractures (called pilon fractures) that damage the joint surface. Researchers will use external fixation (a temporary metal frame outside the skin) to stabilize your ankle while they plan surgery to repair the cartilage damage.
Columbia, MissouriAges 18 years+ - NCT07558564Recruiting
Platelet-Rich Plasma Treatment for Chronic Tendon Pain
This trial tests whether an injection of concentrated platelets from your own blood can help heal chronic tendon injuries that haven't improved with other treatments. Platelets contain natural healing factors that may reduce pain and improve function.
A CoruñaAges 18 years+ - NCT07551999Recruiting
Voice Analysis Tool for ME/CFS Diagnosis and Monitoring
This study tests a smartphone app that analyzes your voice to help diagnose and track myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a condition causing extreme tiredness and other symptoms. Researchers want to see if voice patterns can be a simple, at-home way to monitor your condition over time.
Rochester, MinnesotaAges 18 years+ - NCT07552298Recruiting
Dextrose Injection for Long-Term Tailbone Pain
This study tests whether injecting dextrose (a sugar solution) into the tailbone area can relieve chronic tailbone pain that hasn't improved with standard treatments like physical therapy or medications. If it works, it could offer patients a minimally invasive option to reduce pain and improve daily function.
IstanbulAges 18–65 - NCT07558850Recruiting
CAR-T Cell Therapy for Treatment-Resistant Autoimmune Diseases
This study tests a new type of immune cell therapy (CAR-T cells) designed to treat severe autoimmune diseases like rheumatoid arthritis, lupus, dermatomyositis, and scleroderma that haven't responded well to standard treatments. The therapy works by modifying your own immune cells to target and eliminate the B cells that are causing your autoimmune disease.
Nanjing, JiangsuAges 18–70 - NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT07554118Recruiting
Balance and Walking Study for Older Adults
This research study examines how older adults maintain balance and walk. Researchers want to understand what helps people stay steady on their feet as they age, which could lead to better ways to prevent falls.
Oklahoma City, OklahomaAges 65–80 - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.