Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07405983Recruiting
New study of a thumb joint replacement for arthritis
This study tests a new implant (TOUCH® CMC) for people with thumb arthritis. It aims to see if the implant relieves pain and improves function.
Aurora, ColoradoAges 22 years+ - NCT05806021RecruitingPhase 4
Tested different cortisone doses for knee osteoarthritis pain
This trial compares different doses of injected cortisone (triamcinolone) directly into the knee to see which dose helps knee osteoarthritis pain most. You may be enrolled in a group receiving a 5 mg, 10 mg, or 40 mg dose if you meet the study’s knee and health requirements.
Montreal, QuebecAges 50 years+ - NCT07403084Recruiting
Study of NEMOST V2 implant for children with scoliosis
This study looks at how well the NEMOST V2 implant works to straighten the spine in children with scoliosis that is getting worse despite other treatments. It may help kids whose spine curve is severe and needs surgery.
Nice, Provence-Alpes-Côte d'Azur RegionAges 5–17 - NCT04042844RecruitingPhase 2
Single injection treatment for chronic low back disc pain
This Phase 2 study tests whether one injection of BRTX 100 can reduce pain and improve function in people with chronic, disc-related low back pain. It looks for whether the treatment is safe and works better than what you’ve already tried.
Birmingham, AlabamaAges 18 years+ - NCT06212856Recruiting
Plyometric training for young male volleyball players
This study tests whether 8 weeks of plyometric (jump-based) exercises can improve fitness and volleyball skills in young male players. If you are a healthy man aged 18-25 who has played volleyball for at least 6 months and have not had an injury last month, you may be able to join.
IslamabadAges 18–25 - NCT06802120Recruiting
Osteopathic care after lower back surgery
This trial tests whether osteopathic treatments can help reduce pain and improve daily life after spinal fusion surgery. It is for people who still have ongoing mechanical back pain four weeks after surgery.
ParisAges 18–75 - NCT06943131Recruiting
Exercises for children with shoulder blade movement issues
This study tests two exercise programs—YWTL exercises and close kinetic chain exercises—for children with a shoulder blade movement problem. It aims to find which exercises help reduce pain and improve arm function.
Lahore, Punjab ProvinceAges 9–12 - NCT05081453Recruiting
Early testing and treatment for a specific hip-knee problem
This trial focuses on healthy newborns who were born breech to identify early signs of a knee-tilt/track problem and start treatment sooner if needed. It may help reduce how much the condition affects walking later by addressing it early.
MurciaAges birth–6 months - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+ - NCT07394582Recruiting
Pre-surgery optimization for hip or knee replacement
This trial tests a program to improve your health before hip or knee replacement surgery. It aims to help you recover better and reduce risks.
Innsbruck, TyrolAges 18–99 - NCT07391488Enrolling by invitation
Lumbopelvic rhythm & posture in scoliosis
This study looks at how the way your lower back and pelvis move together affects your balance, daily activities, and quality of life if you have scoliosis. It aims to find better ways to help you move and feel better.
Ankara, ÇorumAges 10–18 - NCT07391410Recruiting
A registry study for bone metastases
This study is creating a registry to track information about people with bone metastases (cancer that has spread to the bones) who need treatment for symptoms. It may help researchers learn more about these conditions.
Basking Ridge, New JerseyAges 22 years+ - NCT07389681Recruiting
Bone loss repair: Masquelet technique vs transport nails
This study compares two surgical techniques for rebuilding bone in the lower leg or thigh after significant bone loss. If you need this type of surgery, you may be able to join and help doctors learn which method works best.
BordeauxAges 18 years+ - NCT07389096RecruitingPhase 4
Pain relief without opioids for teens having spine surgery
This trial tests if a drug combination that avoids opioids can safely control pain during and after scoliosis surgery in teenagers. It aims to reduce opioid side effects and improve recovery.
Port SaidAges 8–18 - NCT06453291Recruiting
Comparing treatments for chronic low back pain
This study compares different ways to treat chronic low back pain that has lasted more than 3 months. It aims to find which approach works best for adults aged 40 to 60.
LahoreAges 40–60 - NCT06884644Recruiting
Oxygen levels during death by squats
This study looks at how the oxygen levels in your blood and muscles change during a tough squat exercise called 'death by squats.' It may help us understand how the body handles intense exercise.
Munich, BavariaAges 18 years+ - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT06396650Recruiting
Fall Prevention Program for Older Adults at Risk
This study tests a fall-prevention program that is tailored to your specific balance and walking needs. It's for people aged 60–85 who have fallen at least once or feel unsteady, and it aims to help them reduce their risk of falling.
Baltimore, MarylandAges 60–85 - NCT06569836Recruiting
Study on digital program for chronic knee pain
This trial tests a digital program to help people manage chronic knee pain. If you are 55 or older and have had knee pain recently, this study may be a good fit.
Hong KongAges 55 years+ - NCT05020028RecruitingPhase 2/Phase 3
CBD to reduce knee pain from osteoarthritis
This study tests cannabidiol (CBD) to help lower pain from knee osteoarthritis. It may be an option if you have ongoing knee pain and meet age, safety, and medication guidelines.
New York, New YorkAges 40–75 - NCT07379801Recruiting
Ballet dancers with scoliosis: A study on bone health and exercise
This study looks at how scoliosis affects the bones and muscles of young female ballet dancers during puberty. It also tests whether a special exercise program can help. Eligible dancers will be followed for a year.
HaifaAges 11–16 - NCT07438535Recruiting
Blood flow restriction training for sprinters
This study tests whether using a special band that partly restricts blood flow during leg exercises can help competitive sprinters build strength or speed. You would do a 6-week training program with either high or low effort, or just the band, to see what works best.
Lahore, Punjab ProvinceAges 18–30 - NCT07378215RecruitingPhase 4
Steroids for better recovery after hip replacement
This study tests whether a single dose of steroids (dexamethasone) given during hip replacement surgery can improve your recovery and quality of life. It may help reduce pain and swelling after the procedure.
Genk, LimburgAges 60 years+ - NCT06940453Recruiting
A new cage for spinal fusion surgery
This trial is testing a new device called the CONDUIT cage for a type of back surgery called anterior lumbar interbody fusion (ALIF). The surgery helps treat degenerative disc disease in the lower back by fusing two vertebrae together using a cage to support the spine. The study will see how well this cage works in patients who are already scheduled for this surgery.
Dublin, LeinsterAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.