Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07528300Recruiting
Acupuncture for pain relief in muscle injury patients
This study tests whether a type of acupuncture called "battlefield acupuncture" can help reduce pain in people hospitalized with rhabdomyolysis—a serious muscle injury that causes muscle breakdown and pain. Researchers want to see if this treatment helps patients feel better while they're in the hospital.
TAMC, HawaiiAges 18–99 - NCT05610878RecruitingPhase 1
Stem cell help to improve fat grafting results
This early-phase study tests whether “preconditioned” stem cells from fat tissue can improve the look of fat transferred during liposuction and grafting. If you qualify, you may receive stem cells along with fat grafting to see how well it works and how safe it is.
Lahore, Punjab ProvinceAges 18–50 - NCT05922462Recruiting
Greek yogurt study in young athletes
This study tests whether eating more Greek yogurt affects health in youth and young adult athletes. It may help researchers understand benefits and safety for active people.
St. Catharines, OntarioAges 15–22 - NCT06753019Recruiting
Knee Osteoarthritis: Thoughts, Feelings, and Function
This study looks at how your thoughts and feelings about knee pain (and your daily function) relate to osteoarthritis. It aims to help understand your overall health better.
IspartaAges 40–84 - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT06500364RecruitingPhase 4
Knotless implants for hip capsule closure study
This study tests a new knotless device for closing the hip capsule during hip arthroscopy. It may help patients heal better after surgery.
Des Plaines, IllinoisAges 18–60 - NCT06755138Recruiting
Scoliosis, pain, and quality of life in Duchenne muscular dystrophy
This study looks at how scoliosis (curved spine) and back pain affect daily life in people with Duchenne muscular dystrophy. Researchers will measure muscle strength and compensation patterns to understand these links.
SeoulAges 11–30 - NCT07517575RecruitingPhase 2
Olokizumab for Children with Juvenile Idiopathic Arthritis
This trial tests a new medicine called olokizumab in children and teenagers with juvenile idiopathic arthritis (JIA)—a condition where the immune system causes joint inflammation and pain. The study checks if this drug is safe and effective for children whose arthritis hasn't improved enough with standard treatments.
Kazan'Ages 2–17 - NCT07517250Recruiting
Study of Canakinumab for Fever and Joint Disease
This is a study looking back at patients who were already treated with a medicine called canakinumab for familial Mediterranean fever or Still's disease (rare conditions that cause fevers and joint pain). Researchers want to understand how well this medicine worked over time and what happened to patients who took it.
BaselAges 1 year+ - NCT07518615Recruiting
Safety and Effectiveness of Guided Dental Implant Surgery System
This trial tests a new computer-guided system (Straumann Dynamic Navigation Falcon) that helps dentists place dental implants more precisely. If you need one or more dental implants and have healthy gums and jaw, this study may help determine if this guided approach is safe and works well.
GhentAges 18 years+ - NCT07524244Recruiting
Ketogenic and carnivore diets for IBD and rheumatoid arthritis
This study tests whether special diets (ketogenic or carnivore/meat-based) can help reduce inflammation and symptoms in people with inflammatory bowel disease or rheumatoid arthritis. You'll follow dietary guidelines for 3 weeks, then continue in the study while researchers track how you respond.
Charlottesville, VirginiaAges 18–64 - NCT07517172Recruiting
Brain Stimulation Patch for Jaw Pain: Home Treatment Study
This study tests whether a small, stick-on electrical patch placed on your ear can reduce temporomandibular disorder (TMD) jaw pain when used at home. You would apply the patch yourself and complete surveys about your pain to help researchers learn if this non-invasive approach is safe and feasible.
Minneapolis, MinnesotaAges 18–65 - NCT07516574Enrolling by invitation
Exercise program before scoliosis surgery in teens
This trial tests whether doing special exercises before spine surgery helps teens with adolescent idiopathic scoliosis (a sideways curve of the spine). The goal is to see if pre-surgery exercise improves how patients recover and feel after surgery.
Edmonton, AlbertaAges 10–18 - NCT07523893Recruiting
Shockwave therapy versus exercises for tennis elbow
This study compares two treatments for lateral epicondylitis (tennis elbow): shockwave therapy and eccentric exercises. It aims to see which approach works better for reducing pain and improving arm function.
IslamabadAges 20–50 - NCT07516769RecruitingPhase 3
Nicorandil to reduce inflammation in active rheumatoid arthritis
This study tests whether nicorandil, a heart medication with anti-inflammatory properties, can help reduce joint inflammation and swelling in people with active rheumatoid arthritis who are already taking conventional disease-modifying drugs. The goal is to see if it provides additional relief from symptoms.
Tanta, Gharbia GovernorateAges 18–70 - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT07522398Recruiting
Power Training Study for Adults Over 65
This study tests whether short, intense strength exercises can help older adults build muscle and stay stronger. You'll do exercises designed to build power (the ability to move quickly and forcefully) over several weeks, and researchers will measure changes in your strength and daily function.
Diepenbeek, FlandersAges 65–85 - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+ - NCT07520669Recruiting
Shoulder Surgery to Prevent Too Much Rotation
This study tests whether a surgical technique called capsuloplasty can prevent excessive external rotation (outward twisting) of the shoulder after surgery for recurrent shoulder dislocation. The goal is to help contact sport athletes return to activity safely.
MérignacAges 18–50 - NCT07516652Recruiting
Comparing two surgical approaches for trigger finger
This trial tests two different surgical techniques for treating trigger finger, a condition where a finger gets stuck or clicks when you bend it. The study compares the outcomes of two ways surgeons can release the tight tissue causing the problem.
Chicago, IllinoisAges 18 years+ - NCT07517757Recruiting
Diet strategies for fibromyalgia in overweight women
This study tests whether specific eating plans can help reduce fibromyalgia symptoms (widespread pain and fatigue) in women who are overweight or obese. Fibromyalgia causes chronic body pain and tiredness, and this trial explores whether changing diet may improve how you feel.
Genova, GenovaAges 18–65 - NCT07520721Recruiting
Shoulder Replacement Materials: Plastic vs Hybrid Implants
This trial compares two types of shoulder replacement implants for people with long-standing shoulder arthritis. It tests whether a hybrid design (combining different materials) works better than a traditional plastic design for pain relief and shoulder function.
Hoofddorp, North HollandAges 18 years+ - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.