Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT06805942Recruiting
Embolization for heel pain from plantar fasciitis
This study tests a minimally invasive procedure called embolization to reduce heel pain caused by plantar fasciitis. It blocks tiny blood vessels in the painful area, which may relieve pain and help you walk more comfortably.
Falls Church, VirginiaAges 22–100 - NCT06910696Enrolling by invitation
Comparing two nerve blocks for lumbar disc surgery pain
This trial tests two types of nerve blocks to see which one works better for pain control after lumbar disc surgery. It may help reduce pain and the need for strong pain medicines after your operation.
ZagazigAges 21–64 - NCT06902714RecruitingPhase 3
Tranexamic acid for shoulder replacement recovery
This study tests whether taking an oral medicine called tranexamic acid (TXA) before and after shoulder replacement surgery can reduce bleeding and improve recovery. It is for adults scheduled for a total shoulder replacement who are generally healthy.
Birmingham, AlabamaAges 18–79 - NCT07283276Recruiting
Core training vs cognitive training for ankle instability
This study tests whether special core exercises or mental training can help improve your balance and control after repeated ankle sprains. If you have chronic ankle instability, this could help you find which type of training works best.
CairoAges 18–30 - NCT06502626Recruiting
Sprint interval training for field hockey players
This trial tests whether short, intense sprint workouts can improve performance for field hockey players. If you are an active player aged 18–30, this study could help you get faster and fitter on the field.
Lahore, Punjab ProvinceAges 18–30 - NCT07284615Recruiting
Nerve Block vs. Wound Injection for Hip Replacement Pain
This trial compares two pain-relief methods after hip replacement surgery: a nerve block (numbing the hip area) versus a numbing injection into the wound. The goal is to see which provides better pain control.
Cinisello Balsamo, MilanoAges 18 years+ - NCT07282782RecruitingPhase 4
Vancomycin for knee replacement surgery
This trial is testing the antibiotic vancomycin to prevent infections after total knee replacement. It may help if you are having your first knee replacement and are not severely overweight or diabetic.
San Diego, CaliforniaAges 18 years+ - NCT07282522Recruiting
Sensory and function in cervical disc herniation
This study looks at how cervical disc herniation affects sensation and daily function. If you have had neck pain for at least 3 months and have been diagnosed with cervical disc herniation, researchers want to compare your results to people without neck pain.
Iğdır, IğdirAges 18–65 - NCT07172360RecruitingPhase 3
Study of VC005 tablets for active ankylosing spondylitis
This trial tests a new tablet called VC005 to see if it helps reduce pain and stiffness in people with active ankylosing spondylitis. It's a phase 3 study, meaning it's one of the final steps before the drug may be approved for wider use.
Beijing, Beijing MunicipalityAges 18–70 - NCT07347054Recruiting
Trigger point injection for shoulder arthritis pain
This study tests whether injecting a medication into painful knots in the shoulder muscle can reduce pain from shoulder arthritis. It may be a good option if you have had shoulder pain for at least 3 months and other treatments haven't worked well enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT06920654Enrolling by invitation
Shoulder stabilization surgery study
This study looks at the long-term results of a specific shoulder surgery (Latarjet-like procedure) to treat chronic shoulder dislocations. It aims to understand how well the shoulder stays stable years after the surgery.
DrammenAges 18 years+ - NCT07277517Recruiting
Pain education plus physical therapy for new back pain
This study tests whether adding Pain Neuroscience Education (learning how your brain and nerves process pain) to standard physical therapy can help people with new low back pain feel better and move more easily. It's for adults whose pain started within the past 6 weeks and who do not have a serious spine condition.
TehranAges 18 years+ - NCT06928103Recruiting
Comparing warm-up routines for athletes with shoulder tightness
This study compares different warm-up routines for athletes with tightness in the back of the shoulder. It aims to find which warm-up best improves shoulder movement and may help prevent injuries.
TaipeiAges 18–40 - NCT07175714Recruiting
Study of walking stumbles and slips
This study tests how well different methods can recreate stumbles and slips while walking. It may help people with and without prosthetic legs understand how to prevent falls.
ReykjavikAges 18 years+ - NCT07276334Enrolling by invitation
Same-day discharge vs. hospital stay for wrist fracture surgery
This trial compares going home the same day after wrist fracture surgery versus staying in the hospital. It aims to see if same-day discharge is safe and effective for recovery.
Ẕerifin, IsraelAges 18–120 - NCT07274423Recruiting
Deep learning for clearer ankle MRI scans
This study tests if a new deep learning technology can improve the quality of ankle MRI images. It may help people with ankle injuries get a more accurate diagnosis.
Wuhan, HubeiAges 18 years+ - NCT06298812Recruiting
A study of the REFLECT Scoliosis System for teens with scoliosis
This study tests a device called the REFLECT Scoliosis System, meant to treat growing teens with progressive idiopathic scoliosis that hasn't improved with bracing. It may help correct the curve and allow you to follow a normal recovery plan after surgery.
Rochester, MinnesotaAges Any age - NCT06900933Recruiting
Bone graft for upper jaw using jawbone blocks
This trial tests using a small piece of bone from your lower jaw to rebuild a narrow upper jaw so it can hold a dental implant. It compares using the bone alone versus covering it with a collagen membrane to see which works better.
CairoAges 20–40 - NCT06962046Recruiting
Can virtual reality improve knee replacement surgery results?
This trial tests if using virtual reality (VR) during knee replacement surgery can help improve your recovery. You wear a VR headset during the procedure to relax and distract you, which may lead to better outcomes.
BelfastAges 18–100 - NCT06933004Recruiting
Long-term follow-up after lumbar spine surgery
This study will follow patients who have surgery for lower back problems. It aims to learn about their long-term recovery and outcomes.
TaipeiAges 20–80 - NCT06816862Recruiting
New surgical system for neck and upper back instability
This study tests a new surgical system called SYMPHONY OCT, designed to stabilize the neck and upper back. If you have instability from a fracture, failed fusion, or tumor, this trial may help find a better treatment option.
Dublin, LeinsterAges 18 years+ - NCT07128043Enrolling by invitation
Cassava wax baths for trigger finger pain and function
This study tests whether warm baths made from cassava (tapioca) wax can reduce pain, improve hand function, and help with the catching or locking feeling in people with trigger finger. If you have trigger finger and no other major hand problems, this treatment may offer a gentle, non-surgical option.
Chiang Rai, Tha SutAges 40–70 - NCT05966220Recruiting
Follow-up study after hip replacement using company devices
This study checks how well FH ORTHO hip surgery devices perform after implantation in participating hospital centers. You may be asked to take part because you already received one of these approved hip devices.
Guilherand-GrangesAges 18 years+ - NCT06930287Recruiting
Shoe Effects for Runners with Tight Calves
This study looks at how different types of running shoes affect runners with tight calf muscles (functional equinus). It explores whether certain footwear can help improve comfort or performance.
SalamancaAges 18–50
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.