Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,841 recruiting studies in this area right now.
By phase
- Not applicable3,975
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 274
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California210
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,841 total
- NCT07061223Enrolling by invitation
Comparing two nerve block methods for hip replacement surgery
This trial tests two types of nerve blocks (SFIB and PENG) to find which provides better anesthesia during total hip replacement. It may help you understand which pain control approach could work best for your surgery.
MoscowAges 50–75 - NCT06509711Recruiting
Jump training on sand for volleyball players
This study tests whether jumping exercises on sand can help volleyball players jump higher and move better. If you are a healthy male player, this may help improve your game.
Lahore, Punjab ProvinceAges 17–35 - NCT06940037Recruiting
Aging biology and strength training in older adults
This study looks at how aging affects the way older adults respond to resistance training (exercises using weights or resistance bands). It compares two types of training to see which works better for improving mobility and strength.
Boston, MassachusettsAges 65 years+ - NCT06669494Enrolling by invitation
Study on ICU muscle weakness detection and monitoring
This study aims to find better ways to detect and track muscle weakness that can happen during an ICU stay. If you or your loved one is in the ICU, this research could help improve early diagnosis and care.
Seoul, SeoulAges 18 years+ - NCT05959980Recruiting
Neck surgery or collar for Hirayama disease
This trial compares two ways to manage Hirayama disease: cervical fixation surgery versus wearing a neck collar. It’s designed to see which option better controls symptoms over the following months.
New Delhi, National Capital Territory of DelhiAges 18–60 - NCT06942819Enrolling by invitation
MRI study of VersaWrap nerve protector after back surgery
This trial uses MRI scans to see how well a nerve protector called VersaWrap works after one-level lumbar decompression surgery. It may help understand if the device helps nerves heal better.
Austin, TexasAges 18–65 - NCT05757999RecruitingPhase 2/Phase 3
Magnesium before surgery to reduce muscle relaxation side effects
This trial tests whether giving magnesium sulfate before elective ear, nose, and throat (ENT) surgery can change how much your muscles relax during anesthesia. It may help doctors find a smoother, safer balance of muscle relaxation for some patients.
Asyut, Asyut GovernorateAges 18–60 - NCT07258537Enrolling by invitation
Comparing two hand therapies for sacroiliac joint pain
This study compares two types of hands-on therapy (a gentle side-lying adjustment vs. a lower back roll) to see which works better for long-lasting low back pain caused by the sacroiliac joint. If you have ongoing pain and are open to physical treatments, this trial may help find the best approach.
Gujrat, Punjab ProvinceAges Any age - NCT07189819Recruiting
Closed-loop FES system for improving walking after stroke
This study tests a new electrical stimulation system that adapts in real time to help people who have had a stroke walk better. It may improve your step and make walking feel more natural.
Atlanta, GeorgiaAges 40–90 - NCT06948656Recruiting
How low blood sugar affects muscle loss in cirrhosis
This study looks at whether low blood sugar (hypoglycemia) is linked to muscle loss (sarcopenia) in people with cirrhosis. It may help doctors better manage your health if you have this liver condition.
DijonAges 18 years+ - NCT06470503Enrolling by invitation
Exercise after radiation for bone metastases
This study tests whether a supervised exercise program helps people with cancer that spread to their bones feel stronger and move better after radiation treatment. It is designed for people who can walk independently and have stable bones.
Toronto, OntarioAges 18 years+ - NCT06518265Recruiting
Locked nail surgery for high-risk ankle fractures
This study looks at how well a special locking nail works for ankle fractures in patients with skin problems or injuries that make standard surgery risky. It aims to find out who benefits most from this less invasive method.
La TroncheAges 18–100 - NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT06910228Enrolling by invitation
Brain oxygen changes during spine surgery position shifts
This study measures how your child's brain oxygen levels change when they are repositioned during spine surgery. It may help make surgeries safer for teens and young adults.
Columbus, OhioAges 10–21 - NCT05683314Recruiting
Surgery comparison for unstable pelvic and hip socket fractures
This study looks at how to best surgically fix unstable pelvic and acetabular (hip socket) fractures, comparing different operative approaches. You might benefit if your goal is stable healing with a less invasive internal fixation method, but the study requires specific fracture types and long follow-up time.
Taichung, North DistrictAges Any age - NCT07739082Recruiting
Virtual reality for teens with hunched back
This study tests if virtual reality exercises can improve posture in teens with a hunched back (thoracic hyperkyphosis). It may help by making therapy more engaging and effective.
CairoAges 13–18 - NCT07737912Enrolling by invitation
SpinePal app for spine fusion recovery
This study tests a smartphone app called SpinePal along with a wrist fitness tracker to help you recover after spine fusion surgery. If you qualify, you'll use the app and tracker for a few months to see if they improve your recovery and reduce pain.
Lebanon, New HampshireAges 18 years+ - NCT07367854Recruiting
Diet and muscle building in active women
This trial tests how different foods or diet patterns work together to help your body build more muscle protein. It’s designed for active, pre-menopausal women who are not pregnant and have regular cycles.
Urbana, IllinoisAges 19–40 - NCT07222787Recruiting
Testing a new spinal implant for lower back fusion
This trial tests a new spinal implant system (CORUS-LX) for fusing two lower back discs that are causing pain. It is meant for people with severe, long-lasting back or leg pain that hasn't improved with non-surgical treatments.
Scottsdale, ArizonaAges 18–80 - NCT07248514Recruiting
Pilates for kids with backpack-related back pain
This study tests if Pilates exercises can help children aged 12-16 who have back pain and poor posture from carrying heavy backpacks.
Lahore, Punjab ProvinceAges 12–16 - NCT06660329Enrolling by invitationPhase 4
Tofacitinib for hard-to-treat Blau syndrome
This study tests if the drug tofacitinib (a JAK inhibitor) can help people with Blau syndrome whose symptoms did not improve with other treatments. Blau syndrome is a rare genetic condition that causes inflammation in the skin, joints, eyes, and other organs.
BeijingAges birth–18 years - NCT06826898Recruiting
Hydrogel to prevent scar tissue after ankle ligament repair
This trial tests a special gel placed during ankle ligament repair surgery to see if it prevents painful scar tissue from forming. It might help people with chronic ankle sprains who need surgery.
ChanghuaAges 18–60 - NCT07735416Recruiting
Football players hamstring injury training study
This study is checking how football players' sprint, agility, balance, and body awareness change after training, depending on whether they have had a hamstring injury before. It will help understand how to prevent future injuries.
IstanbulAges 18–35 - NCT07244081Recruiting
Movement therapy for arm use in children with cerebral palsy
This study tests whether a type of physical therapy called kinesiotherapy can improve arm and hand function and daily living skills in children with hemiplegic cerebral palsy (weakness on one side). It may help children who can follow simple directions and participate in therapy sessions.
Sialkot, Punjab ProvinceAges 8–13
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,841 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,937 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.