Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06901141Enrolling by invitation
Kinesio Tape for Balance, Ankle, and Jumping
This study tests whether different types of kinesio tape (a flexible tape placed on the skin) can improve balance, ankle function, and jumping ability in healthy young adults. It may help you if you are a physiotherapy student looking to understand how taping affects movement.
Istanbul, BüyükçekmeceAges 18–25 - NCT06734364Recruiting
Buddy tape vs. splint for finger bone fracture recovery
This study compares two non-surgical ways to treat a broken bone in the hand (metacarpal shaft fracture) that is not out of place. It tests whether taping the injured finger to a neighbor (buddy tape) works as well as using a padded splint.
Corbeil-EssonnesAges 18 years+ - NCT06758986Enrolling by invitation
Gender and shoulder pain study
This study looks at whether gender affects shoulder pain from subacromial impingement. It may help tailor future treatments.
Kırşehir, MerkezAges 18–65 - NCT05860673Recruiting
Minimally invasive vs standard surgery for adolescent scoliosis
This study compares a less invasive surgical approach with the usual back surgery for adolescent idiopathic scoliosis (a sideways spine curve that starts in the teen years). It aims to see which approach works better and is easier to recover from.
BolognaAges 12–25 - NCT05877014RecruitingPhase 3
Compare two fixation methods for adult arm shaft fractures
This trial tests whether one surgical technique (for stabilizing the upper-arm bone using a rod placed inside the bone) works better than another for adult humeral shaft fractures. It may help find the approach that leads to better healing and recovery.
DijonAges 18 years+ - NCT07146724Enrolling by invitation
Pilates for tight hamstrings in young adults
This study tests if Pilates-based exercises can help loosen tight hamstring muscles in young adults. You would follow an 8-week program and we would measure how your flexibility improves.
Yalova, YalovaAges 18–35 - NCT06874413Enrolling by invitation
Exercise program for frail older adults before hernia surgery
This study tests whether a supervised exercise program before hernia repair surgery helps frail older adults recover better. The program includes physical exercises and breathing muscle training.
Greenville, South CarolinaAges 65 years+ - NCT06887816Recruiting
Silver-coated implants to prevent infection
This trial tests if a new silver-coated prosthesis reduces infections after surgery. It is for patients with weakened immune systems or diabetes.
Bologna, BOAges 18 years+ - NCT06868147Recruiting
Long-term results of a second ACL reconstruction using a tendon graft
This study looks at people who had a second surgery to fix a torn ACL in their knee. The surgery used a special technique with a tendon from the Achilles. Researchers want to see how well the knee works and looks on X-rays at least 2 years after that surgery.
BolognaAges 18–50 - NCT05856370Recruiting
Study for follow-up of Medtronic spine or skull devices
This study checks how well certain Medtronic devices for the skull or spine are working in real-world care. If you’re getting one of these devices, you may be asked to do scheduled follow-up visits and assessments to confirm safety and performance.
Tucson, ArizonaAges 18 years+ - NCT05868434Recruiting
Surgery for unstable kneecap after dislocation
This trial looks at a surgical repair to stop a kneecap (patella) that keeps slipping out of place after a lateral dislocation. It’s intended for people whose symptoms did not improve with non-surgical treatments.
Bełchatów, Łódź VoivodeshipAges 18 years+ - NCT03839758Recruiting
Personalized implant study for shoulder arthritis
This study looks at a personalized implant/instrument setup for people having shoulder replacement due to wear-and-tear arthritis (and bone tissue death). It aims to see whether customizing the surgery approach improves outcomes over time, including up to 2 years.
Montreal, QuebecAges 18–99 - NCT06627699Recruiting
Study of the Freedom Total Knee System for knee replacement
This study is for people getting a total knee replacement for the first time. It looks at how well the Freedom Total Knee System works in everyday life.
Leawood, KansasAges 18 years+ - NCT07451210Recruiting
Blood flow restriction therapy after ankle ligament surgery
This study tests whether a special blood flow restriction device used during physical therapy helps people recover better after ankle ligament repair. You would do physical therapy as usual, but with a cuff on your upper leg that gently limits blood flow during exercises, which may help strengthen muscles more quickly.
Lubbock, TexasAges 18–65 - NCT06818448Recruiting
Comparing rotator cuff repair methods for small tears
This trial compares two surgical techniques for repairing small rotator cuff tears (up to 2 cm). It tests if a newer method helps people recover better than the standard approach.
MechernichAges 18 years+ - NCT06836934Enrolling by invitation
Knee brace vs. wedge for osteoarthritis
This study compares two non-surgical options—a soft knee brace vs. a lateral wedge shoe insert—to see which better relieves pain and improves function in people with knee osteoarthritis. If you're between 40 and 60 and have pain on one side of your knee, this study may help you find better relief.
Giza, Giza GovernorateAges 40–60 - NCT06835608Recruiting
Schroth exercise for kyphosis and chronic neck pain
This study tests whether an exercise program called Schroth (which strengthens back muscles) can improve your posture, reduce neck pain, and make daily activities easier. It is for people with a hunched upper back (kyphosis) and long-lasting neck pain.
Ankara, ÇankayaAges 20–50 - NCT07682051Enrolling by invitation
Resistance training for patellar tendon pain
This study tests whether resistance training can improve the health of the patellar tendon in people with patellar tendinopathy (pain at the knee cap). It may help you recover strength and reduce pain over time.
Graz, StyriaAges 18–50 - NCT06831045Recruiting
Bikini vs Straight Incision for Hip Replacement
This study compares two types of skin cuts (a bikini-line incision vs a straight side incision) for total hip replacement through the front of the hip. It is designed for people with a BMI of 30 or higher to see which incision heals better and leads to fewer wound problems.
Miami, FloridaAges 18 years+ - NCT06828016Recruiting
Foot Reflexology for Chronic Low Back Pain
This study tests whether foot reflexology—a gentle massage of the feet—can help relieve chronic low back pain that has lasted more than 12 weeks. It is a safe, non-drug approach that may be a good option for people looking for a natural way to manage their pain.
New Taipei CityAges 18–100 - NCT07030582Recruiting
Online therapy for back pain and recovery after spinal fusion
This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.
Nantong, JiangsuAges 18–55 - NCT06821607Recruiting
Telerehab for chronic low back pain
This study tests if online rehabilitation therapy can help people with ongoing low back pain. You would connect with a specialist from home.
Baltimore, MarylandAges 18–64 - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT07146074Recruiting
Early radiation vs. observation for high-risk bone metastases
This trial tests whether giving radiation therapy early to high-risk but pain-free or nearly pain-free bone metastases can prevent future problems, compared to waiting and monitoring them. It is for people whose cancer has spread to multiple bones and who have certain risky features in those spots.
Wilrijk, AntwerpAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.