Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT06925880Recruiting
Can creatine help seniors recover strength after knee replacement?
This trial tests if taking creatine supplements can help people aged 65+ rebuild muscle mass and strength more quickly after total knee replacement surgery. Participants will take creatine during their standard outpatient rehab program.
Mataró, BarcelonaAges 65 years+ - NCT06715709Enrolling by invitationPhase 4
How many doses of dexamethasone before knee replacement?
This trial compares different numbers of doses of dexamethasone (a steroid that reduces inflammation) given around the time of knee replacement surgery. It aims to find the best balance of pain control and side effects.
Rochester, MinnesotaAges 18 years+ - NCT06774157Enrolling by invitation
Allyane therapy for knee sprain recovery
This trial tests if the Allyane procedure helps people with a recent knee sprain regain thigh muscle strength. It may be an option if you have weakness in the front thigh muscle compared to your uninjured leg.
LyonAges 18–35 - NCT06921889Recruiting
Outcomes of cartilage cell repair in the knee
This study follows adults who are already scheduled for ACI surgery (a procedure that uses your own cartilage cells to repair knee injuries). It measures how well the knee works after surgery.
BirminghamAges 18 years+ - NCT06041321Recruiting
Testing a new sleeve for knee surgery recovery
This trial tests a special sleeve designed to help reduce pain and improve recovery after knee surgery for a torn meniscus. It may be a good option if you are having this type of knee surgery and are in generally good health.
Woodbury, New YorkAges 18–89 - NCT06737237Enrolling by invitation
Nerve block vs. local numbing for collarbone surgery
This trial compares two ways to numb the area during collarbone surgery: a nerve block (cervical plexus block) or local anesthetic injections. The goal is to see which provides better pain relief and recovery.
Marine Corps Base Camp Lejeune, North CarolinaAges 18–64 - NCT06919913Recruiting
Probiotics for joint infection surgery
This study tests if taking probiotics before and after surgery can help your immune system fight infection in a hip or knee replacement. You would be given a probiotic or a placebo alongside your standard treatment.
New York, New YorkAges 18–90 - NCT06917365Recruiting
Testing a new liner for SERF hip replacements
This trial is testing a new liner (the inner part) for a specific brand of hip replacement called SERF. It's looking at how well it works in people who need a total hip replacement.
DijonAges 18 years+ - NCT07470307Recruiting
Exercise for chronic low back pain: Pilates vs. strength training
This trial compares dynamic lumbar strengthening exercises to Pilates, both combined with myofascial release, for people with ongoing low back pain. It aims to find which approach works better for reducing pain and improving function.
Lahore, Punjab ProvinceAges 25–35 - NCT07058662RecruitingPhase 1/Phase 2
Gene therapy study for Duchenne muscular dystrophy in boys 4-8
This study tests a new gene therapy called BBM-D101 for boys with Duchenne muscular dystrophy. The goal is to see if it is safe and can help improve muscle function. It is for boys aged 4 to 8 who can still walk.
Beijing, Beijing MunicipalityAges 4–9 - NCT06741514Enrolling by invitation
Parent survey on Precice limb lengthening
This trial asks parents of children who have already had limb lengthening with the Precice system to share their thoughts on how well the procedure worked. Your answers can help doctors understand the benefits of this treatment.
West Palm Beach, FloridaAges Any age - NCT07741227Recruiting
Electric acupuncture for chronic neck pain
This study tests whether electric acupuncture can reduce stiffness and pain in the neck muscles. It may be a treatment option if you have had neck pain for at least 3 months and would like to try a non-drug approach.
Hong KongAges 18–65 - NCT06888895Recruiting
Stretching for tight hamstrings in low back pain
This study compares two types of hamstring stretching techniques (passive vs. active-passive) to see which one improves flexibility more in people with chronic low back pain. It may help you if your hamstrings feel tight and your pain has lasted at least 3 months.
Cébazat, FranceAges 18–65 - NCT06913088Recruiting
Ultrasound bubbles bandage for hand arthritis
This trial tests a special bandage that uses ultrasound and tiny bubbles to treat arthritis pain and stiffness in your hands. If you have hand arthritis with at least three painful finger or wrist joints, you may be able to join.
Taichung, TaichungAges 20 years+ - NCT06912269Recruiting
Strength training for the calf after Achilles tendon rupture
This trial tests if strength training can improve calf muscle function in men who tore their Achilles tendon (up to 5 years ago) and had surgery. You cannot have done regular calf exercises recently or have certain health conditions.
Porto Alegre, Rio Grande do SulAges 18–64 - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT06909916Recruiting
Weight-Bearing CT for Knee Fractures Above a Replacement
This study uses a special weight-bearing CT scan to look at how well the bone around a repaired knee fracture heals after a second surgery. If you’ve had surgery for a broken bone above your knee replacement, this scan might help doctors learn more about your recovery.
London, OntarioAges 50–90 - NCT06714110Enrolling by invitation
Review of Limb Lengthening with Precice Nail or External Fixator in Children
This study looks back at records of children, age 12 or younger, who had surgery to lengthen a leg bone using the Precice nail or an external fixator. The goal is to understand how well these treatments work for kids with a leg length difference of at least 2 cm.
West Palm Beach, FloridaAges birth–12 years - NCT06906783Recruiting
Comparing two ways to fix a shifted meniscus in the knee
This trial compares two surgical techniques to see which better treats a meniscus that has moved out of place (extruded) in the knee, which can cause pain and limited movement. It aims to find the best approach to relieve symptoms and improve knee function.
Erzurum, YakutiyeAges 18–65 - NCT07418632Recruiting
Motion training for neck pain using smart classification
This study tests a special motion-training program for people with neck pain. It uses a computer to classify and guide your movements, which may help reduce pain better than usual care.
LjubljanaAges 18–65 - NCT06905093Recruiting
Exercise types for recovery after shoulder surgery
This study compares two types of exercise for your non-surgical arm while your shoulder recovers from surgery in a sling. The goal is to see which helps you regain strength and motion better.
Toulon, VarAges 18 years+ - NCT06903416RecruitingPhase 2/Phase 3
Nerve stimulation for arm and hand function after spinal cord injury
This study tests a non-invasive, painless nerve stimulation technique to see if it can improve arm and hand function after a spinal cord injury. It may help people who have had a neck-level injury more than 9 months ago.
Edmonton, AlbertaAges 18–75 - NCT07291310Enrolling by invitation
Virtual reality therapy for children with brachial plexus injury
This trial tests if playing virtual reality games while doing dual tasks can help the brain rewire and improve arm function in children with a brachial plexus injury. It could offer a fun and engaging new approach to rehabilitation.
Istanbul, CevizlibağAges 7–14 - NCT06306326Recruiting
Using 3D scanning to check fat grafting for facial defects
This study uses 3D face scanning to see how well your own fat, taken from another part of your body, can restore fullness to your face. It might help if you have a sunken or uneven look from a birth defect, injury, or aging.
Beijing, Beijing MunicipalityAges 3–80
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.