Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT06728462Recruiting
Calcium supplement study for postmenopausal women with osteoporosis
This study tests a new form of calcium (amorphous calcium carbonate) to see if it can improve bone density in postmenopausal women with osteoporosis. It may offer an alternative for women who cannot or choose not to take other osteoporosis medications.
Kaohsiung CityAges 60–90 - NCT06749080Recruiting
Assist 2.0: a program for healthy ageing at home
This trial tests a program called ASSIST 2.0 to help older adults stay active and independent at home. If you receive homecare, this program might help you manage daily tasks and improve your quality of life.
Huddinge, SwedenAges 65 years+ - NCT07327775Recruiting
ADHD and fibromyalgia in mothers
This study looks at how having fibromyalgia affects mothers who also have a child with ADHD. It compares them to mothers of children without ADHD to see if the burden of care is different.
EdirneAges 18–50 - NCT07332182Recruiting
MaioRegen scaffold for deep knee cartilage injuries
This study tests a special scaffold (MaioRegen Prime) that helps regrow cartilage and bone in deep knee injuries. It is for people who have not gotten better with physical therapy and need a repair option.
La Mesa, CaliforniaAges 18–60 - NCT07325578Recruiting
Testing a new device for CT-guided spine and pelvis procedures
This study is testing a new device called EPIONE that helps doctors perform CT-guided needle procedures in the spine or pelvis. It aims to see if the device improves accuracy and safety for patients under general anesthesia.
San Diego, CaliforniaAges 22 years+ - NCT07331272RecruitingPhase 1
CAR T-cells for lupus and myositis
This trial tests a new treatment using your own immune cells (CAR T-cells) targeted at a marker called CD19. It is for people whose lupus or myositis has not been controlled by other treatments.
Bengbu, AnhuiAges 18–70 - NCT06864130RecruitingPhase 4
Stopping Alendronate in osteoporosis after no fractures
This study wants to see if it is safe for postmenopausal women with osteoporosis to stop taking Alendronate after a long period of treatment without any new fractures. If you have been on Alendronate for a while and have stayed fracture-free, you may be able to take a break from the medicine.
AalborgAges Any age - NCT07331207Recruiting
3D-printed expander for narrow upper jaw in young adults
This study tests a new 3D-printed expander that attaches to bone to widen a narrow upper jaw in young adults. It may help if you have a crossbite or need more room in your upper jaw.
Al MansurahAges 18–30 - NCT07330011Recruiting
Study on measuring patient assistance after joint surgery
This study tests if training staff improves how they measure the level of help patients need after hip or knee surgery. It may help standardize care for these patients.
BolognaAges 18 years+ - NCT07325513Recruiting
Brain stimulation for Gulf War-related pain
This study tests whether a type of brain stimulation (repeated transcranial magnetic stimulation, or rTMS) can help reduce headaches and body pain in veterans with Gulf War Illness. If you are a Gulf War veteran with ongoing moderate-to-severe pain, this trial could help find a new way to manage your symptoms.
San Diego, CaliforniaAges 18–65 - NCT07327892Recruiting
Comparing pain relief methods for hip surgery in older adults
This study compares three different ways to manage pain after hip surgery in older adults. One group gets a nerve block behind the hip, another gets the block plus a numbing injection around the joint, and the third gets only the numbing injection. The goal is to find the best method to reduce pain and help you recover more comfortably.
PoznanAges 65–100 - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07333560Recruiting
Predicting recovery after hip or knee replacement
This study is developing a tool that uses machine learning to predict how well you will recover after hip or knee replacement surgery. It aims to help doctors create better recovery plans for people like you.
BolognaAges 18 years+ - NCT07331298Recruiting
Water movement in spine discs of children
This study uses routine MRI scans to measure water movement in the spine discs of children aged 8–16. It aims to understand normal disc health and how it changes in children with scoliosis (a curve in the spine).
LimogesAges 8–16 - NCT07327931Recruiting
Comparing two PENG block recipes for hip surgery in older adults
This study tests two different types of local numbing medicine (with and without extra additives) for a nerve block called PENG block in older adults having hip surgery. The goal is to find which method controls pain better and reduces the need for strong pain relievers.
PoznanAges 65–100 - NCT07326163Enrolling by invitation
Peppermint oil aromatherapy for fibromyalgia pain relief
This study tests whether smelling peppermint oil can help reduce pain and improve daily function in people with fibromyalgia, while also looking at cost. It uses a simple, non-invasive method (aromatherapy) to see if it can be a helpful addition to your current care.
Bilecik, BilecikAges 18 years+ - NCT07329361Recruiting
Frozen platelet-rich plasma injections for knee osteoarthritis
This trial tests whether frozen platelet-rich plasma (PRP) injections into the knee can safely reduce pain and improve function in people with knee osteoarthritis. It's for those with mild to moderate knee arthritis who haven't had certain recent knee treatments.
Vitoria-Gasteiz, Araba/ÁlavaAges 40–85 - NCT07330999Recruiting
PENG block variants with and without extra medications for older adults undergoing hip surgery
This trial tests three ways of doing a PENG block (a type of pain relief injection for hip surgery) with or without added medications (adjuvants) to see which works best for older adults. It aims to improve pain control and reduce the need for other pain medicines after surgery.
PoznanAges 65–100 - NCT07327372Recruiting
Numbing with sedation for hip surgery in older adults
This trial tests a numbing injection (called a PENG block) plus a sedative (dexmedetomidine) for older adults having hip surgery. The goal is to see if this combination gives better pain relief and fewer side effects.
PoznanAges 65–100 - NCT07328269Recruiting
Mulligan vs Maitland technique for jaw pain relief
This trial compares two manual therapy methods (Mulligan and Maitland) to improve jaw movement and reduce pain in people with temporomandibular joint (TMJ) dysfunction. If you have limited jaw opening or jaw pain, you may be able to join.
Islamabad, Punjab ProvinceAges 19–44 - NCT07329426Recruiting
Muscle energy therapy with mobilization for sacral torsion
This trial tests if combining muscle energy therapy with spinal mobilization can relieve pain and correct misalignment in people with a twisted pelvic bone (sacral torsion). It may help reduce pain and improve mobility.
Islamabad, Punjab ProvinceAges 22–44 - NCT07328295Recruiting
Does adding spine mobilization help frozen shoulder treatment?
This trial tests if adding thoracic spine mobilization to standard shoulder mobilization reduces pain and improves movement and function in people with frozen shoulder (adhesive capsulitis) at stages 2 or 3.
Islamabad, Punjab ProvinceAges 40–65 - NCT07329530Recruiting
Muscle and metabolism study in ICU survivors
This study looks at muscle and metabolism changes in people who have been in the ICU for at least 7 days after major abdominal surgery. It aims to understand how recovery affects the body.
LiègeAges 18 years+ - NCT07329023Recruiting
Acupressure for Knee Arthritis in Older Chinese Adults
This trial tests whether learning self-administered acupressure (a type of massage using fingertips) can help older Chinese adults with knee arthritis manage their pain and stiffness without medication. If you join, you will receive training in a community setting and use a smartphone app to track your progress.
KowloonAges 60 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.