Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07331207Recruiting
3D-printed expander for narrow upper jaw in young adults
This study tests a new 3D-printed expander that attaches to bone to widen a narrow upper jaw in young adults. It may help if you have a crossbite or need more room in your upper jaw.
Al MansurahAges 18–30 - NCT07327372Recruiting
Numbing with sedation for hip surgery in older adults
This trial tests a numbing injection (called a PENG block) plus a sedative (dexmedetomidine) for older adults having hip surgery. The goal is to see if this combination gives better pain relief and fewer side effects.
PoznanAges 65–100 - NCT07330011Recruiting
Study on measuring patient assistance after joint surgery
This study tests if training staff improves how they measure the level of help patients need after hip or knee surgery. It may help standardize care for these patients.
BolognaAges 18 years+ - NCT07333560Recruiting
Predicting recovery after hip or knee replacement
This study is developing a tool that uses machine learning to predict how well you will recover after hip or knee replacement surgery. It aims to help doctors create better recovery plans for people like you.
BolognaAges 18 years+ - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07330999Recruiting
PENG block variants with and without extra medications for older adults undergoing hip surgery
This trial tests three ways of doing a PENG block (a type of pain relief injection for hip surgery) with or without added medications (adjuvants) to see which works best for older adults. It aims to improve pain control and reduce the need for other pain medicines after surgery.
PoznanAges 65–100 - NCT07329530Recruiting
Muscle and metabolism study in ICU survivors
This study looks at muscle and metabolism changes in people who have been in the ICU for at least 7 days after major abdominal surgery. It aims to understand how recovery affects the body.
LiègeAges 18 years+ - NCT07328295Recruiting
Does adding spine mobilization help frozen shoulder treatment?
This trial tests if adding thoracic spine mobilization to standard shoulder mobilization reduces pain and improves movement and function in people with frozen shoulder (adhesive capsulitis) at stages 2 or 3.
Islamabad, Punjab ProvinceAges 40–65 - NCT07329023Recruiting
Acupressure for Knee Arthritis in Older Chinese Adults
This trial tests whether learning self-administered acupressure (a type of massage using fingertips) can help older Chinese adults with knee arthritis manage their pain and stiffness without medication. If you join, you will receive training in a community setting and use a smartphone app to track your progress.
KowloonAges 60 years+ - NCT07333417Recruiting
Rigid taping for acromioclavicular joint degeneration
This study tests whether a special rigid tape applied to the shoulder can reduce pain and improve function in people with acromioclavicular (AC) joint degeneration. The AC joint is where your collarbone meets the top of your shoulder blade, and this condition can cause pain and stiffness.
Ankara, AnkaraAges 18–65 - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT07330921Recruiting
Testing a new 3D seating system for kids with motor issues
This trial is testing a new 3D seating system designed for children with motor control problems. It aims to see if this system helps them sit better and be more comfortable.
Zaragoza, ZaragozaAges 2–6 - NCT07326475Enrolling by invitation
Soccer training study for boys ages 11-13
This study looks at how different soccer training methods affect movement and performance in young male players. It may help coaches understand which training techniques work best.
GdanskAges 11–13 - NCT07333989Recruiting
Biofeedback training for balance in older adults with osteoporosis
This study tests whether biofeedback (using sensors to help you control your body movements) can improve balance in older adults with osteoporosis. If you have low bone density and are between 65-75 years old, this trial may help you strengthen your balance and reduce fall risk.
Abū ḨummuşAges 65–75 - NCT03675087Recruiting
Testing how exercise affects symptoms in ME/CFS
This trial studies how people with ME/CFS respond to an exercise test. It may help researchers understand what kind of exercise response is typical and how it relates to symptoms.
MadridAges 18–65 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT05356286Recruiting
Recording spinal cord stimulation and monitoring during surgery
This study records what happens when doctors use spinal cord monitoring and stimulation during brain or spinal cord surgery. It may help improve how safely these procedures are performed in the future.
Los Angeles, CaliforniaAges 18 years+ - NCT05314491Recruiting
Follow-up study after knee replacement with a specific implant
This study follows people after they get a total knee replacement using the Multigen Plus system, sometimes with special cone pieces. It looks at how well the implant performs over time and whether results meet expectations.
GuimarãesAges 18 years+ - NCT06224959Recruiting
Migraine and nerve pain in osteoarthritis study
This study looks at whether people with osteoarthritis also have migraine headaches or nerve pain. Researchers want to better understand these connections to improve treatment.
Clermont-Ferrand, FranceAges 18 years+ - NCT06858293Recruiting
Imagining exercises to boost knee strength after ACL surgery
This study tests whether imagining yourself doing exercises can help you regain strength in your thigh muscle after ACL surgery, and if it's something people can stick with during physical therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06156813Recruiting
Turkish lower limb movement log for stroke patients
This study aims to adapt a questionnaire that measures how well stroke survivors can use their legs in daily life. It may help doctors better understand your recovery and guide your rehabilitation.
GaziantepAges 18–80 - NCT06074900Recruiting
Waiting for hip or knee replacement study
This study follows people waiting for hip or knee replacement surgery due to osteoarthritis. It helps researchers understand how to better support patients during the wait.
London, OntarioAges 18 years+ - NCT06222671RecruitingPhase 2
A study of 608 for non-radiographic axial spondyloarthritis
This study tests a new medicine called 608 for people with non-radiographic axial spondyloarthritis (a type of inflammatory back pain). The goal is to see if it can reduce pain and inflammation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06494618Recruiting
Botulinum toxin plus shockwave for leg spasticity in cerebral palsy
This study tests if combining botulinum toxin injections with radial extracorporeal shockwave therapy (RESWT) works better than injection alone for reducing leg spasticity in children with cerebral palsy. If your child has spasticity in leg muscles and is already receiving botulinum toxin, they may benefit from this additional therapy.
Istanbul, KadikoyAges 2–18
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.