Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT01238250Recruiting
Online autism genetics study for families with certain genetic changes
This study asks people with specific genetic changes linked to autism and their family members to complete online tasks and questionnaires. It may help researchers better understand how these genetic differences relate to autism traits.
Boston, MassachusettsAges Any age - NCT07278804Recruiting
Pain control options for IUD insertion
This study tests different pain control choices during IUD placement. It may help you find what works best for your comfort.
Durham, North CarolinaAges 18–50 - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT06371417RecruitingPhase 1
Testing RAY121 for several immune diseases (RAINBOW trial)
This trial tests a new medicine called RAY121 (an antibody) for people with certain autoimmune diseases. It aims to see if RAY121 is safe and how the body handles it. If you have one of these conditions and meet the basic health requirements, you might be able to join.
Orange, CaliforniaAges 18–85 - NCT07028177Recruiting
Etomidate dose for surgery in people with insomnia
This study looks at how much etomidate (a sleep-inducing medicine used during surgery) is needed for people with insomnia compared to those who sleep normally. It aims to help doctors give safer and more effective doses for patients with insomnia who need general anesthesia.
Beijing, Beijing MunicipalityAges 18–64 - NCT07719517Recruiting
Morning activities to boost mood after stroke
This study tests if doing simple, guided activities in the morning can help improve your mood after a stroke. If you often feel down and have trouble getting going in the morning, this program might offer a way to feel better.
Hong KongAges 18 years+ - NCT02328573Recruiting
Group singing for people after stroke and their caregivers
This study looks at whether group singing can help people who have had a stroke and support the people who care for them. If you or your caregiver are interested in group singing, this may be a simple way to try the intervention while contributing to research.
New York, New YorkAges 18 years+ - NCT07718958Recruiting
Biomarkers for PANS in children
This study looks for blood markers that could help diagnose and track pediatric acute-onset neuropsychiatric syndrome (PANS). If your child has PANS, participating could help improve understanding and treatment of this condition.
Cagliari, CagliariAges 3–18 - NCT06897007Recruiting
Ciprofol dosage in patients with insomnia under anesthesia
This study looks at how the sedative drug ciprofol works differently in people with insomnia compared to those who sleep well. It aims to help doctors give the right dose for your type of surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07720336Recruiting
Essential oils and a wearable device for long-term nausea
This study tests whether a wearable device (like a wristband) and essential oils can help calm chronic nausea. It focuses on people who have had nausea for more than 6 months, feel it at least 3 times a week, and also have anxiety.
Columbus, OhioAges 18 years+ - NCT06194305RecruitingPhase 2
Brain and behavior study of tic therapy for kids
This study tests a behavioral therapy (CBIT) for children with tics. It uses brain scans (MRI and EEG) to see how the therapy works. It may be a good fit for a child who has had tics for at least a year and hasn't had much of this therapy before.
San Diego, CaliforniaAges 10–17 - NCT07720700Recruiting
Foot orthoses and walking in people with ataxia
This study tests if special shoe inserts (foot orthoses) can help improve walking in people with ataxia. You may qualify if you have trouble with balance or coordination while walking.
Dallas, TexasAges 18 years+ - NCT07028190Recruiting
Rimazolen dose in insomnia patients under anesthesia
This trial looks at how much Rimazolen, a sleep medicine, is needed during surgery for people with insomnia compared to normal sleepers. It aims to find the right dose for better recovery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07721025RecruitingPhase 2
Gene therapy trial for Friedreich ataxia heart disease
This trial tests a one-time gene therapy called LX2006 for heart problems caused by Friedreich ataxia. The goal is to see if it can improve heart function and structure.
Tampa, FloridaAges 6 years+ - NCT07710625Recruiting
Heat sensitivity scale for Parkinson's disease
This study is testing a new questionnaire to measure how heat affects people with Parkinson's disease. If you have Parkinson's and notice changes with heat, this may help doctors better understand your symptoms.
Istanbul, TurkeyAges 40–85 - NCT07718750Recruiting
AI text messages for better sleep
This study tests if personalized text messages generated by artificial intelligence can help improve sleep. You may join if you have trouble sleeping and use a smartphone.
New York, New YorkAges 18–75 - NCT07719595Recruiting
Vagus nerve stimulation for coma after brain injury
This trial tests if a gentle electrical stimulation of the vagus nerve (a nerve in the neck) can help people regain consciousness after a severe traumatic brain injury. It is for patients who are in a coma or minimally conscious state, and the treatment is given along with standard ICU care.
Stony Brook, New YorkAges 18 years+ - NCT07719712Recruiting
Thinking and confusion after prostate surgery in older adults
This study looks at how older adults' thinking and memory may change after a common prostate surgery, and whether some patients become confused or delirious afterward. It may help doctors understand who is at risk for these problems.
MuğlaAges 65 years+ - NCT07720882Recruiting
Brain implant study to restore hand function after spinal cord injury
This trial tests a fully implanted wireless brain-computer interface (BCI) to help people with paralysis from a neck-level spinal cord injury regain hand and arm movement. The BCI reads brain signals and sends them to your arm, bypassing the damaged spinal cord.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06351592RecruitingPhase 1/Phase 2
Study of ALN-SOD for ALS with SOD1 gene mutation
This trial tests an experimental drug called ALN-SOD for people with ALS caused by a specific genetic mutation in the SOD1 gene. The goal is to see if it is safe and can help slow the disease.
Concord, New South WalesAges 18 years+ - NCT07476937Recruiting
Understanding Sleep and Emotions in Children with Autism
This study looks at how sleep, emotions, and arousal differ in children with autism who have bedtime struggles. If your child is 6 to 10 years old and has trouble falling asleep, this trial may help researchers understand and improve sleep for kids like yours.
Pittsburgh, PennsylvaniaAges 6–10 - NCT05139797Recruiting
AI-guided heart ultrasound screening for suspected amyloidosis
This study tests whether an artificial-intelligence system can help decide who should get a special heart workup for a rare disease called cardiac amyloidosis. If you have signs that make doctors suspect this, the AI-guided ultrasound screening may help find it sooner.
Los Angeles, CaliforniaAges 18 years+ - NCT06214507Recruiting
Danon disease natural history study
This study follows people with Danon disease over time to better understand how the condition progresses. It may help guide future treatments.
Phoenix, ArizonaAges 8 years+ - NCT07449416Recruiting
Ceribell Delirium Monitor Study in ICU Patients
This pilot study tests a special brain monitor (called Ceribell EEG) to see if it can help detect delirium in ICU patients. Delirium is a state of confusion that can happen during a serious illness, and this monitor may help doctors catch it early.
Irvine, CaliforniaAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.