Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT06184295Recruiting
Robotic balance training for better balance after brain injury
This study tests whether training on a robotic device can help improve balance and posture for people who had a traumatic brain injury (TBI) within the last 6 months to 5 years. It may help if you have some balance issues and can stand without support for 5 minutes.
West Orange, New JerseyAges 18–65 - NCT06358495Recruiting
Sleep improvement to prevent depression and anxiety in teens
This study tests if improving sleep can help prevent depression and anxiety in teens who are at higher risk because a parent has had depression or anxiety. It's for teens who have trouble sleeping but don't have a history of depression or anxiety themselves.
Calgary, AlbertaAges 12–18 - NCT06718842Recruiting
Walking program for children with PKU and fatty liver
This study tests whether a walking program can help children with PKU who also have fatty liver and obesity. It aims to see if regular walking improves liver health and overall fitness.
Dokki, Giza GovernorateAges 9–12 - NCT04630873RecruitingPhase 1
Botox dilution options for walking in hemiplegic gait
This Phase 1 study tests whether using a lower or higher dilution of Botox injections improves walking in people with hemiplegic gait. The goal is to see which dilution works better (and is safe) for walking and leg stiffness.
IoanninaAges 18 years+ - NCT06718075Recruiting
Comparing tools to predict stroke risk after a mini-stroke
This study looks at two ways to estimate your chance of having a stroke after a transient ischemic attack (a mini-stroke). You will be asked some questions, and your risk will be calculated using both methods. The goal is to see which tool is more accurate for patients like you.
BolognaAges 18 years+ - NCT04556227Recruiting
Exercise and memory training after ICU delirium
This study tests whether combining gentle cycling while lying down with tablet-based memory exercises can improve recovery after ICU delirium. It may help people regain thinking and comfort after a hospital stay.
Kansas City, MissouriAges 45–64 - NCT02533804Recruiting
Life Project study for adults in Lake Nona
This study is collecting information from adults living or working in the Lake Nona area. It may help researchers understand community needs and improve programs for residents.
Orlando, FloridaAges 18–110 - NCT04936646Recruiting
Brain stimulation study for long-term nerve pain
This trial tests whether a form of brain stimulation (rTMS) can reduce chronic nerve pain that has lasted more than a year and hasn’t improved with standard treatments. It may help people whose usual pain medicines are stable but still not working well.
Grenoble, IsèreAges 18–80 - NCT05625438Recruiting
Home video therapy for early arm recovery after stroke
This study tests a home-based (telerehabilitation) program to help people practice arm movement after a recent stroke (or certain brain injuries). It may help improve arm function when started soon after symptoms begin.
Fullerton, CaliforniaAges 18 years+ - NCT05908149Recruiting
Gait analysis with a shoe insole splint after stroke
This study checks how a special shoe insole splint affects walking patterns in people recovering from a stroke. It’s looking at gait (walking) measurements to see whether the splint can help safely during physical therapy.
IoanninaAges 18–70 - NCT07593313Recruiting
Treatment for pain after stroke using spinal stimulation
This trial tests a treatment called spinal cord stimulation for people who develop chronic pain after a stroke. The pain is caused by the stroke itself and doesn't respond well to regular pain medicines. The treatment uses a small device to send mild electrical signals to your spinal cord to reduce pain.
Nanchong, SichuanAges 18 years+ - NCT07589595RecruitingPhase 2
Donanemab for Early Cognitive Decline with Lewy Bodies
This study tests donanemab, an investigational drug designed to target amyloid proteins in the brain that may contribute to cognitive decline in people with early dementia with Lewy bodies. The trial aims to see if this treatment can slow cognitive decline and help preserve thinking and memory.
Chandler, ArizonaAges 55–85 - NCT07594158RecruitingPhase 3
ONO-2017 for Seizures in Japanese Children and Teens
This study tests a new seizure medication called ONO-2017 in Japanese children and teenagers (ages 2–17) who have a specific type of seizure called POS that hasn't been controlled by current medicines. The goal is to see if this new drug is safe and helps reduce these seizures.
FukuokaAges 2–17 - NCT07589257RecruitingPhase 2
VRT106 drug combined with radiation for brain stem tumors
This trial tests whether a new drug called VRT106, given alongside radiation therapy, can help treat a serious type of brain tumor called diffuse midline glioma or DIPG. The drug is designed to work with radiation to fight the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07587242RecruitingPhase 3
Testing a New Therapy for DMD with Exon 44 Mutations
This study tests whether a new medicine called AOC 1044 (delpacibart zotadirsen) can help boys with Duchenne muscular dystrophy (DMD) who have a specific genetic mutation. The medicine works by helping the body skip a damaged part of the gene to make a functional protein.
Westmead, New South WalesAges 7–16 - NCT05725174Recruiting
Study seizure signals using quick, non-invasive breath tests
This study looks for “volatile” (gaseous) body signals from breath to help identify seizure events. If you were recently admitted for seizure diagnosis, you may be asked to provide breath samples in a non-invasive way.
London, BuckinghamshireAges 18 years+ - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT05906056Recruiting
CPM therapy vs bone overgrowth in hip or knee
This study compares continuous passive motion (a machine that gently moves a joint without you moving it) versus the body’s tendency to form extra bone called heterotopic ossification. It aims to see whether CPM can affect how and how much bone overgrowth develops after neurologic injuries like stroke, brain injury, or spinal cord injury.
Ioannina, EpirusAges 15–70 - NCT06339957Recruiting
Rheumatology diet study for arthritis and related conditions
This study looks at how diet affects people with different types of arthritis and related autoimmune conditions. If you are a UCF Health patient between 18 and 65, you may be able to help researchers learn more about which foods help or worsen symptoms.
Orlando, FloridaAges 18–65 - NCT05986279Recruiting
MINDGAPS: A balance and mental health study for military members
This study tests a program called MINDGAPS to help Veterans and active-duty service members with their balance and mental health. If you are a military member who can stand on your own and have not had a recent head injury, you may be eligible.
San Diego, CaliforniaAges 18 years+ - NCT06082713Recruiting
Extracellular Vesicles Study for Huntington's Disease
This study is collecting tiny particles called extracellular vesicles from blood and spinal fluid to learn more about Huntington's disease. It aims to find better ways to measure the disease in people who have HD and in those who do not.
Orlando, FloridaAges 18–75 - NCT07587125RecruitingPhase 1
CAR-T Cell Therapy for Progressive Multiple Sclerosis
This trial tests a new cell therapy called S103 for people with MS that isn't responding well to standard treatments. The therapy involves modifying immune cells in the lab and putting them back into your body to help control the disease.
Xi'an, ShaanxiAges 18–75 - NCT07592962Recruiting
Long-term Health Study of Lishui City Residents
This study follows healthy adults in Lishui City over time to understand how people stay healthy and live longer. Researchers will collect health information and track your wellbeing to identify factors that contribute to a long, healthy life.
Lishui, ZhejiangAges 30–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.